Age-related alterations in the expression of MTH2 in the hippocampus of the SAMP8 mouse with learning and memory deterioration

Journal of the Neurological Sciences

Volumn 287, Issue 1-2, 2009, Pages 188-196

  Zheng, Jun De ^a   Hei, Ai Lian ^a   Zuo, Ping Ping ^b   Dong, Yi Long ^b   Song, Xiao Ning ^a   Takagi, Yasumitsu ^c   Sekiguchi, Mutsuo ^c   Cai, Jian Ping ^a  

^a BEIJING HOSPITAL   (China)

^b PEKING UNION MEDICAL COLLEGE   (China)

^c FUKUOKA DENTAL COLLEGE   (Japan)

Author keywords

8 oxo dGTPase; 8 oxoguanine; Aging; Alzheimer's disease; Mouse model; MTH2; Mutation; Oxidative stress

Indexed keywords

8 HYDROXYGUANINE; AMYLOID PRECURSOR PROTEIN; BRAIN PROTEIN; CELL NUCLEUS DNA; PROTEIN MTH2; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEARNING DISORDER; MALE; MEMORY DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; SENESCENCE; SENESCENCE ACCELERATED MOUSE; WESTERN BLOTTING;

AGING; ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DNA; DNA REPAIR; FREE RADICALS; GUANINE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEARNING DISORDERS; MALE; MEMORY DISORDERS; MICE; MICE, NEUROLOGIC MUTANTS; OXIDATIVE STRESS; PHOSPHORIC DIESTER HYDROLASES; WERNER SYNDROME;

EID: 70449099331     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2009.07.027     Document Type: Article

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