Proinflammatory effects of muramyldipeptide on human gingival fibroblasts

Journal of Periodontal Research

Volumn 45, Issue 2, 2010, Pages 193-199

  Hosokawa, I ^a   Hosokawa, Y ^a   Ozaki, K ^a   Yumoto, H ^a   Nakae, H ^a   Matsuo, T ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Chemokine; Human gingival fibroblast; Nucleotide binding oligomerization domain 2; Periodontal disease; Proinflammatory cytokine

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA(1,9 CD)PYRAZOL 6(2H) ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; AUTACOID; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CHROMONE DERIVATIVE; CXCL11 CHEMOKINE; ENZYME INHIBITOR; FLAVONOID; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMIDAZOLE DERIVATIVE; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; MORPHOLINE DERIVATIVE; N ACETYLMURAMYLALANYL DEXTRO ISOGLUTAMINE; NOD2 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PYRIDINE DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CELL CULTURE; CHRONIC PERIODONTITIS; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; FEMALE; FIBROBLAST; GINGIVA; HUMAN; MALE; MIDDLE AGED; PATHOLOGY; PERIODONTAL DISEASE; PERIODONTAL POCKET;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ADULT; ANTHRACENES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES; CELLS, CULTURED; CHEMOKINE CCL2; CHEMOKINE CXCL10; CHEMOKINE CXCL11; CHROMONES; CHRONIC PERIODONTITIS; ENZYME INHIBITORS; FEMALE; FIBROBLASTS; FLAVONOIDS; GINGIVA; HUMANS; IMIDAZOLES; INFLAMMATION MEDIATORS; INTERFERON-GAMMA; INTERLEUKIN-6; INTERLEUKIN-8; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MIDDLE AGED; MORPHOLINES; NOD2 SIGNALING ADAPTOR PROTEIN; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL POCKET; PYRIDINES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77950226403     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2009.01217.x     Document Type: Article

References (25)

1. Chamaillard M, Hashimoto M, Horie Y. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol 2003, 4:702-707.
2. Girardin SE, Boneca IG, Carneiro LA. Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science 2003, 300:1584-1587.
3. Girardin SE, Travassos LH, Herve M. Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2. J Biol Chem 2003, 278:41702-41708.
4. Hugot JP, Chamaillard M, Zouali H. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001, 411:599-603.
5. Ogura Y, Bonen DK, Inohara N. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001, 411:603-606.
6. Miceli-Richard C, Lesage S, Rybojad M. CARD15 mutations in Blau syndrome. Nat Genet 2001, 29:19-20.
7. Girardin SE, Boneca IG, Viala J. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 2003, 278:8869-8872.
8. Inohara N, Ogura Y, Fontalba A. Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 2003, 278:5509-5512.
9. Buckley CD, Pilling D, Lord JM, Akbar AN, Scheel-Toellner D, Salmon M. Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation. Trends Immunol 2001, 22:199-204.
10. Takada H, Mihara J, Morisaki I, Hamada S. Induction of interleukin-1 and -6 in human gingival fibroblast cultures stimulated with Bacteroides lipopolysaccharides. Infect Immun 1991, 59:295-301.
11. Tamura M, Tokuda M, Nagaoka S, Takada H. Lipopolysaccharides of Bacteroides intermedius (Prevotella intermedia) and Bacteroides (Porphyromonas) gingivalis induce interleukin-8 gene expression in human gingival fibroblast cultures. Infect Immun 1992, 60:4932-4937.
12. Sugawara S, Sugiyama A, Nemoto E, Rikiishi H, Takada H. Heterogeneous expression and release of CD14 by human gingival fibroblasts. characterization and CD14-mediated interleukin-8 secretion in response to lipopolysaccharide. Infect Immun 1998, 66:3043-3049.
13. Hatakeyama J, Tamai R, Sugiyama A, Akashi S, Sugawara S, Takada H. Contrasting responses of human gingival and periodontal ligament fibroblasts to bacterial cell-surface components through the CD14/Toll-like receptor system. Oral Microbiol Immunol 2003, 18:14-23.
14. Wang PL, Ohura K, Fujii T. DNA microarray analysis of human gingival fibroblasts from healthy and inflammatory gingival tissues. Biochem Biophys Res Commun 2003, 305:970-973.
15. Okusawa T, Fujita M, Nakamura J. Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6. Infect Immun 2004, 72:1657-1665.
16. Tamai R, Sakuta T, Matsushita K. Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression. Infect Immun 2002, 70:1272-1278.
17. Kanneganti TD, Lamkanfi M, Nunez G. Intracellular NOD-like receptors in host defense and disease. Immunity 2007, 27:549-559.
18. Kawai T, Eisen-Lev R, Seki M, Eastcott JW, Wilson ME, Taubman MA. Requirement of B7 costimulation for Th1-mediated inflammatory bone resorption in experimental periodontal disease. J Immunol 2000, 164:2102-2109.
19. Uehara A, Takada H. Functional TLRs and NODs in human gingival fibroblasts. J Dent Res 2007, 86:249-254.
20. Ryan S, McNicholas WT, Taylor CT. A critical role for p38 map kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation. Biochem Biophys Res Commun 2007, 355:728-733.
21. Hoshi S, Goto M, Kanaya N, Nomoto K, Tanaka H. Regulation of vascular smooth cell proliferation by nuclear factor -kappaB and its inhibitor, I-kappaB. J Biol Chem 2000, 275:883-889.
22. Turner NA, Mughal RS, Warburton P, O'Regan DJ, Ball SG, Porter KE. Mechanism of TNFalpha-induced IL-1alpha, IL-1beta and IL-6 expression in human cardiac fibroblasts: effects of statins and thiazolidinediones. Cardiovasc Res 2007, 76:81-90.
23. Wang L, Luo J, Fu Y, He S. Induction of interleukin-8 secretion and activation of ERK1/2, p38 MAPK signaling pathways by thrombin in dermal fibroblasts. Int J Biochem Cell Biol 2006, 38:1571-1583.
24. Amin MA, Mansfield PJ, Pakozdi A. Interleukin-18 induces angiogenic factors in rheumatoid arthritis synovial tissue fibroblasts via distinct signaling pathways. Arthritis Rheum 2007, 56:1787-1797.
25. Takahashi Y, Isuzugawa K, Murase Y. Up-regulation of NOD1 and NOD2 through TLR4 and TNF-alpha in LPS-treated murine macrophages. J Vet Med Sci 2006, 68:471-478.