Penicillin sulfone inhibitors of class D β-lactamases

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 4, 2010, Pages 1414-1424

  Drawz, Sarah M ^a,b   Bethel, Christopher R ^b   Doppalapudi, Venkata R ^c   Sheri, Anjaneyulu ^c   Pagadala, Sundar Ram Reddy ^c   Hujer, Andrea M ^b   Skalweit, Marion J ^a,b   Anderson, Vernon E ^a   Chen, Shu G ^a   Buynak, John D ^c   Bonomo, Robert A ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^c SOUTHERN METHODIST UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; BETA LACTAMASE; BETA LACTAMASE INHIBITOR; CEFALORIDINE; CLAVULANIC ACID; DVR II 214; JDB ASR II 292; JDB LN 1 255; JDB LN III 26; NITROCEFIN; OXA 1 BETA LACTAMASE; OXA 10 BETA LACTAMASE; OXA 14 BETA LACTAMASE; OXA 17 BETA LACTAMASE; OXA 24 BETA LACTAMASE; OXA 40 BETA LACTAMASE; OXACILLIN; PENICILLIN DERIVATIVE; PENICILLIN G; PIPERACILLIN; SULBACTAM; SULFONE DERIVATIVE; TAZOBACTAM; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME SUBSTRATE; HYDROLYSIS; HYDROPHOBICITY; INHIBITION KINETICS; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CATALYTIC DOMAIN; CEPHALORIDINE; CEPHALOSPORINS; ENZYME INHIBITORS; KINETICS; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; OXACILLIN; PENICILLINS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; SULFONES;

EID: 77950105335     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00743-09     Document Type: Article

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