The synthesis and evaluation of 6-alkylidene-2'β-substituted penam sulfones as β-lactamase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 14, 1999, Pages 1997-2002

  Buynak, John D ^a   A Srinivasa, Rao ^a   Doppalapudi, Venkata Ramana ^a   Adam, Greg ^a   Petersen, Peter J ^a   Nidamarthy, Sirishkumar D ^a  

^a SOUTHERN METHODIST UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE INHIBITOR; PENAM DERIVATIVE; SULFONE DERIVATIVE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL MEMBRANE; CHEMICAL REACTION; CYCLIZATION; DRUG INHIBITION; DRUG POTENTIATION; DRUG STRUCTURE; DRUG SYNTHESIS; OXIDATION; REACTION ANALYSIS;

BETA-LACTAMASES; CLOXACILLIN; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; PENICILLIN RESISTANCE; PIPERACILLIN; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONES;

EID: 0033584195     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00325-X     Document Type: Article

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