메뉴 건너뛰기




Volumn 29, Issue 12, 2010, Pages 1773-1786

Self-association of adenovirus type 5 E1B-55 kDa as well as p53 is essential for their mutual interaction

Author keywords

Adenovirus; E1B 55 kDa; Oligomerization; P53

Indexed keywords

BETA ACTIN; E1B PROTEIN; ENHANCED GREEN FLUORESCENT PROTEIN; MUTANT PROTEIN; OLIGOMER; PROTEIN P53;

EID: 77950099437     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.461     Document Type: Article
Times cited : (3)

References (48)
  • 1
    • 23844438197 scopus 로고    scopus 로고
    • Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes
    • Araujo FD, Stracker TH, Carson CT, Lee DV, Weitzman MD. (2005). Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes. J Virol 79: 11382-11391.
    • (2005) J Virol , vol.79 , pp. 11382-11391
    • Araujo, F.D.1    Stracker, T.H.2    Carson, C.T.3    Lee, D.V.4    Weitzman, M.D.5
  • 2
    • 34250894884 scopus 로고    scopus 로고
    • Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation
    • Baker A, Rohleder KJ, Hanakahi LA, Ketner G. (2007). Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation. J Virol 81: 7034-7040.
    • (2007) J Virol , vol.81 , pp. 7034-7040
    • Baker, A.1    Rohleder, K.J.2    Hanakahi, L.A.3    Ketner, G.4
  • 4
    • 27944464545 scopus 로고    scopus 로고
    • Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus
    • Berk AJ. (2005). Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus. Oncogene 24: 7673-7685.
    • (2005) Oncogene , vol.24 , pp. 7673-7685
    • Berk, A.J.1
  • 5
    • 0023932891 scopus 로고
    • The intracellular distribution of the transformation-associated protein p53 in adenovirus-transformed rodent cells
    • Blair Zajdel ME, Blair GE. (1988). The intracellular distribution of the transformation-associated protein p53 in adenovirus-transformed rodent cells. Oncogene 2: 579-584.
    • (1988) Oncogene , vol.2 , pp. 579-584
    • Blair Zajdel, M.E.1    Blair, G.E.2
  • 6
    • 4944255743 scopus 로고    scopus 로고
    • Post-translational modification of p53 in tumorigenesis
    • Bode AM, Dong Z. (2004). Post-translational modification of p53 in tumorigenesis. Nat Rev Cancer 4: 793-805.
    • (2004) Nat Rev Cancer , vol.4 , pp. 793-805
    • Bode, A.M.1    Dong, Z.2
  • 7
    • 0035837241 scopus 로고    scopus 로고
    • The role of tetramerization in p53 function
    • Chene P. (2001). The role of tetramerization in p53 function. Oncogene 20: 2611-2617.
    • (2001) Oncogene , vol.20 , pp. 2611-2617
    • Chene, P.1
  • 8
    • 66149114464 scopus 로고    scopus 로고
    • Identification of integrin alpha3 as a new substrate of the adenovirus E4orf6/E1B 55-kilodalton E3 ubiquitin ligase complex
    • Dallaire F, Blanchette P, Groitl P, Dobner T, Branton PE. (2009). Identification of integrin alpha3 as a new substrate of the adenovirus E4orf6/E1B 55-kilodalton E3 ubiquitin ligase complex. J Virol 83: 5329-5338.
    • (2009) J Virol , vol.83 , pp. 5329-5338
    • Dallaire, F.1    Blanchette, P.2    Groitl, P.3    Dobner, T.4    Branton, P.E.5
  • 9
    • 0024591335 scopus 로고
    • IgM\molecular requirements for its assembly and function
    • 127-128
    • Davis AC, Shulman MJ. (1989). IgM\molecular requirements for its assembly and function. Immunol Today 10: 118-122; 127-128
    • (1989) Immunol Today , vol.10 , pp. 118-122
    • Davis, A.C.1    Shulman, M.J.2
  • 11
    • 0017365468 scopus 로고
    • The binding constants of IgM rheumatoid factors and their univalent fragments for native and aggregated human IgG
    • Dissanayake S, Hay FC, Roitt IM. (1977). The binding constants of IgM rheumatoid factors and their univalent fragments for native and aggregated human IgG. Immunology 32: 309-318.
    • (1977) Immunology , vol.32 , pp. 309-318
    • Dissanayake, S.1    Hay, F.C.2    Roitt, I.M.3
  • 12
    • 0030753963 scopus 로고    scopus 로고
    • Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence
    • Dobbelstein M, Roth J, Kimberly WT, Levine AJ, Shenk T. (1997). Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence. EMBO J 16: 4276-4284.
    • (1997) EMBO J , vol.16 , pp. 4276-4284
    • Dobbelstein, M.1    Roth, J.2    Kimberly, W.T.3    Levine, A.J.4    Shenk, T.5
  • 13
    • 0030001373 scopus 로고    scopus 로고
    • Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor
    • Dobner T, Horikoshi N, Rubenwolf S, Shenk T. (1996). Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor. Science 272: 1470-1473.
    • (1996) Science , vol.272 , pp. 1470-1473
    • Dobner, T.1    Horikoshi, N.2    Rubenwolf, S.3    Shenk, T.4
  • 14
    • 34447628045 scopus 로고    scopus 로고
    • Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-bind-ing protein 2 into aggresomes
    • Fleisig HB, Orazio NI, Liang H, Tyler AF, Adams HP, Weitzman MD et al. (2007). Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-bind-ing protein 2 into aggresomes. Oncogene 26: 4797-4805.
    • (2007) Oncogene , vol.26 , pp. 4797-4805
    • Fleisig, H.B.1    Orazio, N.I.2    Liang, H.3    Tyler, A.F.4    Adams, H.P.5    Weitzman, M.D.6
  • 15
    • 0029840632 scopus 로고    scopus 로고
    • Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells
    • Goodrum FD, Shenk T, Ornelles DA. (1996). Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells. J Virol 70: 6323-6335.
    • (1996) J Virol , vol.70 , pp. 6323-6335
    • Goodrum, F.D.1    Shenk, T.2    Ornelles, D.A.3
  • 16
    • 0036226061 scopus 로고    scopus 로고
    • Effects of mutations in the adenoviral E1B 55-kilodalton protein coding sequence on viral late mRNA metabolism
    • Gonzalez RA, Flint SJ. (2002). Effects of mutations in the adenoviral E1B 55-kilodalton protein coding sequence on viral late mRNA metabolism. J Virol 76: 4507-4519.
    • (2002) J Virol , vol.76 , pp. 4507-4519
    • Gonzalez, R.A.1    Flint, S.J.2
  • 17
    • 0028967485 scopus 로고
    • The quaternary structure of the adenovirus 12 early region 1B 54 K protein
    • Grand RJ, Mustoe T, Roberts S, Gallimore PH. (1995). The quaternary structure of the adenovirus 12 early region 1B 54 K protein. Virology 207: 255-259.
    • (1995) Virology , vol.207 , pp. 255-259
    • Grand, R.J.1    Mustoe, T.2    Roberts, S.3    Gallimore, P.H.4
  • 18
    • 0036720983 scopus 로고    scopus 로고
    • Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery
    • Harada JN, Shevchenko A, Pallas DC, Berk AJ. (2002). Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery. J Virol 76: 9194-9206.
    • (2002) J Virol , vol.76 , pp. 9194-9206
    • Harada, J.N.1    Shevchenko, A.2    Pallas, D.C.3    Berk, A.J.4
  • 19
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt Y, Maya R, Kazaz A, Oren M. (1997). Mdm2 promotes the rapid degradation of p53. Nature 387: 296-299.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 20
    • 33847271089 scopus 로고    scopus 로고
    • Coping with stress: Multiple ways to activate p53
    • Horn HF, Vousden KH. (2007). Coping with stress: multiple ways to activate p53. Oncogene 26: 1306-1316.
    • (2007) Oncogene , vol.26 , pp. 1306-1316
    • Horn, H.F.1    Vousden, K.H.2
  • 21
    • 0031660984 scopus 로고    scopus 로고
    • RNA-binding activity of the E1B 55-kilodalton protein from human adenovirus type 5
    • Horridge JJ, Leppard KN. (1998). RNA-binding activity of the E1B 55-kilodalton protein from human adenovirus type 5. J Virol 72: 9374-9379.
    • (1998) J Virol , vol.72 , pp. 9374-9379
    • Horridge, J.J.1    Leppard, K.N.2
  • 22
    • 0345471390 scopus 로고    scopus 로고
    • Adenovirus type 5 E4orf3 protein relieves p53 inhibition by E1B-55-kilodalton protein
    • Konig C, Roth J, Dobbelstein M. (1999). Adenovirus type 5 E4orf3 protein relieves p53 inhibition by E1B-55-kilodalton protein. J Virol 73: 2253-2262.
    • (1999) J Virol , vol.73 , pp. 2253-2262
    • Konig, C.1    Roth, J.2    Dobbelstein, M.3
  • 23
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 stability by Mdm2
    • Kubbutat MH, Jones SN, Vousden KH. (1997). Regulation of p53 stability by Mdm2. Nature 387: 299-303.
    • (1997) Nature , vol.387 , pp. 299-303
    • Kubbutat, M.H.1    Jones, S.N.2    Vousden, K.H.3
  • 24
    • 0031702817 scopus 로고    scopus 로고
    • Regulation of Mdm2-directed degradation by the C terminus of p53
    • Kubbutat MH, Ludwig RL, Ashcroft M, Vousden KH. (1998). Regulation of Mdm2-directed degradation by the C terminus of p53. Mol Cell Biol 18: 5690-5698.
    • (1998) Mol Cell Biol , vol.18 , pp. 5690-5698
    • Kubbutat, M.H.1    Ludwig, R.L.2    Ashcroft, M.3    Vousden, K.H.4
  • 25
    • 0032900876 scopus 로고    scopus 로고
    • The adenovirus type 5 E1b 55K and E4 Orf3 proteins associate in infected cells and affect ND10 components
    • Leppard KN, Everett RD. (1999). The adenovirus type 5 E1b 55K and E4 Orf3 proteins associate in infected cells and affect ND10 components. J Gen Virol 80(Part 4): 997-1008.
    • (1999) J Gen Virol , vol.80 , Issue.PART 4 , pp. 997-1008
    • Leppard, K.N.1    Everett, R.D.2
  • 26
    • 59349107940 scopus 로고    scopus 로고
    • The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: P53
    • Levine AJ. (2009). The common mechanisms of transformation by the small DNA tumor viruses: the inactivation of tumor suppressor gene products: p53. Virology 384: 285-293.
    • (2009) Virology , vol.384 , pp. 285-293
    • Levine, A.J.1
  • 27
    • 33748250439 scopus 로고    scopus 로고
    • Crystal structure of SV40 large T-antigen bound to p53: Interplay between a viral oncoprotein and a cellular tumor suppressor
    • Lilyestrom W, Klein MG, Zhang R, Joachimiak A, Chen XS. (2006). Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor. Genes Dev 20: 2373-2382.
    • (2006) Genes Dev , vol.20 , pp. 2373-2382
    • Lilyestrom, W.1    Klein, M.G.2    Zhang, R.3    Joachimiak, A.4    Chen, X.S.5
  • 28
    • 0028303752 scopus 로고
    • Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
    • Lin J, Chen J, Elenbaas B, Levine AJ. (1994). Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. Genes Dev 8: 1235-1246.
    • (1994) Genes Dev , vol.8 , pp. 1235-1246
    • Lin, J.1    Chen, J.2    Elenbaas, B.3    Levine, A.J.4
  • 29
    • 27644504904 scopus 로고    scopus 로고
    • Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex
    • Liu Y, Shevchenko A, Berk AJ. (2005). Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex. J Virol 79: 14004-14016.
    • (2005) J Virol , vol.79 , pp. 14004-14016
    • Liu, Y.1    Shevchenko, A.2    Berk, A.J.3
  • 30
    • 0033523015 scopus 로고    scopus 로고
    • Oligomerization is required for p53 to be efficiently ubiquitinated by MDM2
    • Maki CG. (1999). Oligomerization is required for p53 to be efficiently ubiquitinated by MDM2. J Biol Chem 274: 16531-16535.
    • (1999) J Biol Chem , vol.274 , pp. 16531-16535
    • Maki, C.G.1
  • 31
    • 45749157223 scopus 로고    scopus 로고
    • RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis
    • Marshall LJ, Moore AC, Ohki M, Kitabayashi I, Patterson D, Ornelles DA. (2008). RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. J Virol 82: 6395-6408.
    • (2008) J Virol , vol.82 , pp. 6395-6408
    • Marshall, L.J.1    Moore, A.C.2    Ohki, M.3    Kitabayashi, I.4    Patterson, D.5    Ornelles, D.A.6
  • 32
    • 0031901638 scopus 로고    scopus 로고
    • Adenovirus E1B 55K represses p53 activation in vitro
    • Martin ME, Berk AJ. (1998). Adenovirus E1B 55K represses p53 activation in vitro. J Virol 72: 3146-3154.
    • (1998) J Virol , vol.72 , pp. 3146-3154
    • Martin, M.E.1    Berk, A.J.2
  • 34
    • 0035577765 scopus 로고    scopus 로고
    • Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
    • Querido E, Blanchette P, Yan Q, Kamura T, Morrison M, Boivin D et al. (2001a). Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex. Genes Dev 15: 3104-3117.
    • (2001) Genes Dev , vol.15 , pp. 3104-3117
    • Querido, E.1    Blanchette, P.2    Yan, Q.3    Kamura, T.4    Morrison, M.5    Boivin, D.6
  • 35
    • 0030935013 scopus 로고    scopus 로고
    • Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells
    • Querido E, Marcellus RC, Lai A, Charbonneau R, Teodoro JG, Ketner G et al. (1997). Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells. J Virol 71: 3788-3798.
    • (1997) J Virol , vol.71 , pp. 3788-3798
    • Querido, E.1    Marcellus, R.C.2    Lai, A.3    Charbonneau, R.4    Teodoro, J.G.5    Ketner, G.6
  • 36
    • 0035158586 scopus 로고    scopus 로고
    • Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex
    • Querido E, Morrison MR, Chu-Pham-Dang H, Thirlwell SW, Boivin D, Branton PE. (2001b). Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex. J Virol 75: 699-709.
    • (2001) J Virol , vol.75 , pp. 699-709
    • Querido, E.1    Morrison, M.R.2    Chu-Pham-Dang, H.3    Thirlwell, S.W.4    Boivin, D.5    Branton, P.E.6
  • 37
    • 0031661779 scopus 로고    scopus 로고
    • Inactivation of p53 but not p73 by adenovirus type 5 E1B 55-kilodalton and E4 34-kilodalton oncoproteins
    • Roth J, Konig C, Wienzek S, Weigel S, Ristea S, Dobbelstein M. (1998). Inactivation of p53 but not p73 by adenovirus type 5 E1B 55-kilodalton and E4 34-kilodalton oncoproteins. J Virol 72: 8510-8516.
    • (1998) J Virol , vol.72 , pp. 8510-8516
    • Roth, J.1    Konig, C.2    Wienzek, S.3    Weigel, S.4    Ristea, S.5    Dobbelstein, M.6
  • 38
    • 0020079972 scopus 로고
    • Adenovirus E1b-58 kD tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kD cellular protein in transformed cells
    • Sarnow P, Ho YS, Williams J, Levine AJ. (1982a). Adenovirus E1b-58 kD tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kD cellular protein in transformed cells. Cell 28: 387-394.
    • (1982) Cell , vol.28 , pp. 387-394
    • Sarnow, P.1    Ho, Y.S.2    Williams, J.3    Levine, A.J.4
  • 40
    • 0026446686 scopus 로고
    • Identification of a minimal transforming domain of p53: Negative dominance through abrogation of sequence-specific DNA binding
    • Shaulian E, Zauberman A, Ginsberg D, Oren M. (1992). Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding. Mol Cell Biol 12: 5581-5592.
    • (1992) Mol Cell Biol , vol.12 , pp. 5581-5592
    • Shaulian, E.1    Zauberman, A.2    Ginsberg, D.3    Oren, M.4
  • 41
    • 0035050154 scopus 로고    scopus 로고
    • Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55 K protein
    • Shen Y, Kitzes G, Nye JA, Fattaey A, Hermiston T. (2001). Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55 K protein. J Virol 75: 4297-4307.
    • (2001) J Virol , vol.75 , pp. 4297-4307
    • Shen, Y.1    Kitzes, G.2    Nye, J.A.3    Fattaey, A.4    Hermiston, T.5
  • 42
    • 34249711818 scopus 로고    scopus 로고
    • Hetero-oligomerization with MdmX rescues the ubiquitin/Nedd8 ligase activity of RING finger mutants of Mdm2
    • Singh RK, Iyappan S, Scheffner M. (2007). Hetero-oligomerization with MdmX rescues the ubiquitin/Nedd8 ligase activity of RING finger mutants of Mdm2. J Biol Chem 282: 10901-10907.
    • (2007) J Biol Chem , vol.282 , pp. 10901-10907
    • Singh, R.K.1    Iyappan, S.2    Scheffner, M.3
  • 43
    • 0032556920 scopus 로고    scopus 로고
    • The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells
    • Steegenga WT, Riteco N, Jochemsen AG, Fallaux FJ, Bos JL. (1998). The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells. Oncogene 16: 349-357.
    • (1998) Oncogene , vol.16 , pp. 349-357
    • Steegenga, W.T.1    Riteco, N.2    Jochemsen, A.G.3    Fallaux, F.J.4    Bos, J.L.5
  • 44
    • 0037130170 scopus 로고    scopus 로고
    • Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex
    • Stracker TH, Carson CT, Weitzman MD. (2002). Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature 418: 348-352.
    • (2002) Nature , vol.418 , pp. 348-352
    • Stracker, T.H.1    Carson, C.T.2    Weitzman, M.D.3
  • 45
    • 0030978194 scopus 로고    scopus 로고
    • Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5
    • Teodoro JG, Branton PE. (1997). Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5. J Virol 71: 3620-3627.
    • (1997) J Virol , vol.71 , pp. 3620-3627
    • Teodoro, J.G.1    Branton, P.E.2
  • 46
    • 0033989602 scopus 로고    scopus 로고
    • E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53
    • Wienzek S, Roth J, Dobbelstein M. (2000). E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53. J Virol 74: 193-202.
    • (2000) J Virol , vol.74 , pp. 193-202
    • Wienzek, S.1    Roth, J.2    Dobbelstein, M.3
  • 47
    • 0022221929 scopus 로고
    • Adenovirus serotype determines association and localization of the large E1B tumor antigen with cellular tumor antigen p53 in transformed cells
    • Zantema A, Schrier PI, Davis-Olivier A, van Laar T, Vaessen RT, van der EA. (1985). Adenovirus serotype determines association and localization of the large E1B tumor antigen with cellular tumor antigen p53 in transformed cells. Mol Cell Biol 5: 3084-3091.
    • (1985) Mol Cell Biol , vol.5 , pp. 3084-3091
    • Zantema, A.1    Schrier, P.I.2    Davis-Olivier, A.3    Van Laar, T.4    Vaessen, R.T.5    Van Der, E.A.6
  • 48
    • 0345167026 scopus 로고    scopus 로고
    • Sequestration of p53 in the cytoplasm by adenovirus type 12 E1B 55-kilodalton oncoprotein is required for inhibition of p53-mediated apoptosis
    • Zhao LY, Liao D. (2003). Sequestration of p53 in the cytoplasm by adenovirus type 12 E1B 55-kilodalton oncoprotein is required for inhibition of p53-mediated apoptosis. J Virol 77: 13171-13181.
    • (2003) J Virol , vol.77 , pp. 13171-13181
    • Zhao, L.Y.1    Liao, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.