The adenovirus type 5 E1b 55K and E4 Orf3 proteins associate in infected cells and affect ND10 components

Journal of General Virology

Volumn 80, Issue 4, 1999, Pages 997-1008

  Leppard, Keith N ^a   Everett, Roger D ^b  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b INSTITUTE OF VIROLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN;

ADENOVIRUS 5; ARTICLE; CELL NUCLEUS MATRIX; PRIORITY JOURNAL; VIRUS INFECTION;

EID: 0032900876     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-80-4-997     Document Type: Article

References (54)

1. Anderson, C. W., Schmitt, R. C., Smart, J. E. & Lewis, J. B. (1984). Early region 1b of adenovirus-2 encodes 2 coterminal proteins of 495 and 155 amino-acid residues. Journal of Virology 50, 387-396.
2. Ascoli, C. A. & Maul, G. G. (1991). Identification of a novel nuclear domain. Journal of Cell Biology 112, 785-795.
3. Babiss, L. E., Ginsberg, H. S. & Darnell, J. E. (1985). Adenovirus E1b proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport. Molecular and Cellular Biology 5, 2552-2558.
4. Boddy, M. N., Howe, K., Etkin, L. D., Solomon, E. & Freemont, P. S. (1996). PIC1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia. Oncogene 13, 971-982.
5. Bridge, E. & Ketner, G. (1989). Redundant control of adenovirus late gene expression by early region 4. Journal of Virology 63, 631-638.
6. Bridge, E. & Ketner, G. (1990). Interaction of adenoviral E4 and E1b products in late gene expression. Virology 174, 345-353.
7. Caravokyri, C., Pringle, C. R. & Leppard, K. N. (1993). Human adenovirus type-5 recombinants expressing simian immunodeficiency virus macaque strain Gag antigens. Journal of General Virology 74; 2819-2824.
8. Carvalho, T., Seeler, J. S., Ohman, K., Jordan, P., Pettersson, U., Akusjarvi, G., Carmofonseca, M. & Dejean, A. (1995). Targeting of adenovirus E1a and E4-Orf3 proteins to nuclear matrix-associated PML bodies. Journal of Cell Biology 131, 45-56.
9. Cutt, J. R., Shenk, T. & Hearing, P. (1987). Analysis of adenovirus early region 4 encoded polypeptides synthesized in productively infected cells. Journal of Virology 61, 543-552.
10. De The, H., Lavau, C., Marcho, A., Chomienne, C., Degos, L. & DeJean, A. (1991). The PML-RARα fusion mRNA generated by the t15; 17 translocation in promyelocytic leukemia encodes a functionally altered RAR. Cell 66, 675-684.
11. Dobbelstein, M., Roth, J., Kimberly, W. T., Levine, A. J. & Shenk, T. (1997). Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence. EMBO Journal 16, 4276-4284.
12. Doucas, V., Ishov, A. M., Romo, A., Juguilon, H., Weitzman, M. D., Evans, R. M. & Maul, G. G. (1996). Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure. Genes & Development 10, 196-207.
13. Downey, J. F., Rowe, D. T., Bacchetti, S., Graham, F. L. & Bayley, S. T. (1983). Mapping of a 14,000-dalton antigen to early region 4 of the human adenovirus 5 genome. Journal of Virology 45, 514-523.
14. Dyck, J. A., Maul, G. G., Miller, W. J., Chen, J. D., Kakizuka, A. & Evans, R. M. (1994). A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein. Cell 76, 333-343.
15. Everett, R. D. & Maul, G. G. (1994). HSV-1 IE protein Vmw110 causes redistribution of PML. EMBO Journal 13, 5062-5069.
16. Everett, R. D., Freemont, P., Saitoh, H., Dasso, M., Orr, A., Kathoria, M. & Parkinson, J. (1998). The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110-and proteasome-dependent loss of several PML isoforms. Journal of Virology 72, 6581-6591.
17. Goddard, A. D., Borrow, J., Freemont, P. S. & Soloman, E. (1991). Characterization of a zinc finger gene disrupted by the t15; 17 in acute promyelocytic leukemia. Science 254, 1371-1374.
18. Goodrum, F. D. & Ornelles, D. A. (1997). The early region 1b 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle. Journal of Virology 71, 548-561.
19. Goodrum, F. D., Shenk, T. & Ornelles, D. A. (1996). Adenovirus early region-4 34-kilodalton protein directs the nuclear localization of the early region 1b 55-kilodalton protein in primate cells. Journal of Virology 70, 6323-6335.
20. Graham, F. L., Smiley, J., Russell, W. C. & Nairn, R. (1977). Characteristics of a human cell line transformed by DNA from human adenovirus type 5. Journal of General Virology 36, 59-72.
21. Halbert, D. N., Cutt, J. R. & Shenk, T. (1985). Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host-cell shutoff. Journal of Virology 56, 250-257.
22. Horridge, J. J. & Leppard, K. N. (1998). RNA binding activity of the E1B 55K protein from human adenovirus 5. Journal of Virology 72, 9374-9379.
23. Huang, M.-M. & Hearing, P. (1989a). Adenovirus early region 4 encodes 2 gene products with redundant effects in lytic infection. Journal of Virology 63, 2605-2615.
24. Huang, M.-M. & Hearing, P. (1989b). The adenovirus early region 4 open reading frame 6/7 protein regulates the DNA-binding activity of the cellular transcription factor, E2F, through a direct complex. Genes and Development 3, 1699-3710.
25. Imperiale, M. J., Akusjarvi, G. & Leppard, K. N. (1995). Post-transcriptional control of adenovirus gene expression. Current Topics in Microbiology and Immunology 199(II), 139-187.
26. Ishov, A. M. & Maul, G. G. (1996). The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition. Journal of Cell Biology 134, 815-826.
27. Jones, N. C. & Shenk, T. (1979). Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell 17, 683-689.
28. Kakizuka, A., Miller, W. H., Umesono, U., Warrell, R. P., Frankel, S. R., Murty, V. V. V. S., Dmitrovsky, E. & Evans, R. M. (1991). Chromosomal translocation t15; 17 in acute promyelocytic leukemia fuses RARa with a novel putative transcription factor PML. Cell 66, 663-674.
29. Kelly, C., van Driel, R. & Wilkinson, G. W. G. (1995). Disruption of PML nuclear bodies during human cytomegalovirus infection. Journal of General Virology 76, 2485-2491.
30. Leppard, K. N. (1993). Selective effects on adenovirus late gene expression of deleting the E1b 55K protein. Journal of General Virology 74, 575-582.
31. Leppard, K. N. (1997). E4 gene function in adenovirus, adenovirus vector and adeno-associated virus infections. Journal of General Virology 78, 2131-2138.
32. Leppard, K. N. (1998). Regulated RNA processing and RNA transport during adenovirus infection. Seminars in Virology 8, 301-307.
33. Leppard, K. N. & Shenk, T. (1989). The adenovirus E1b-55 kD protein influences mRNA transport via an intranuclear effect on RNA metabolism. EMBO Journal 8, 2329-2336.
34. 4 viral protein ICP0. Journal of General Virology 75, 1223-1233.
35. Maul, G. G., Guldner, H. H. & Spivack, J. G. (1993). Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene product ICP0. Journal of General Virology 74, 2679-2690.
36. Muller, S., Matunis, M. J. & DeJean, A. (1998). Conjugation of the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus. EMBO Journal 17, 61-70.
37. Nordqvist, K., Ohman, K. & Akusjarvi, G. (1994). Human adenovirus encodes 2 proteins which have opposite effects on accumulation of alternatively spliced mRNAs. Molecular and Cellular Biology 14, 437-445.
38. Obert, S., O'Connor, R. J., Schmid, S. & Hearing, P. (1994). The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complex. Molecular and Cellular Biology 14, 1333-1346.
39. Ohman, K., Nordqvist, K. & Akusjarvi, G. (1993). Two adenovirus proteins with redundant activities in virus growth facilitate tripartite leader mRNA accumulation. Virology 194, 50-58.
40. Ornelles, D. A. & Shenk, T. (1991). Localization of the adenovirus early region 1b 55-kilodalton protein during lytic infection: association with nuclear viral inclusions requires the early region 4 34-kilodalton protein. Journal of Virology 65, 424-439.
41. Pilder, S., Moore, M., Logan, J. & Shenk, T. (1986). The adenovirus E1b-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host-cell mRNAs. Molecular and Cellular Biology 6, 470-476.
42. Reich, N. C., Sarnow, P., Duprey, E. & Levine, A. J. (1983). Monoclonal antibodies which recognise native and denatured forms of the adenovirus DNA binding protein. Virology 128, 480-484.
43. Ross, S. R., Flint, S. J. & Levine, A. J. (1980). Identification of the adenovirus early proteins and their genomic map positions. Virology 100, 419-432.
44. Sacks, W. R. & Schaffer, P. A. (1987). Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture. Journal of Virology 61, 829-839.
45. Sarnow, P., Hearing, P., Anderson, C. W., Reich, N. & Levine, A. J. (1982a). Identification and characterization of an immunologically conserved adenovirus early region 11,000 Mr protein and its association with the nuclear matrix. Journal of Molecular Biology 162, 565-583.
46. Sarnow, P., Sullivan, C. A. & Levine, A. J. (1982b). A monoclonal antibody detecting the Ad5 E1b 58K tumor antigen: characterization of the E1b 58K tumor antigen in adenovirus infected and transformed cells. Virology 120, 510-517.
47. Sarnow, P., Hearing, P., Anderson, C. W., Halbert, D. N., Shenk, T. & Levine, A. J. (1984). Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells. Journal of Virology 49, 692-700.
48. Sternsdorf, T., Jensen, K. & Will, H. (1997). Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1. Journal of Cell Biology 139, 1621-1634.
49. Stow, N. D. & Stow, E. C. (1986). Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate-early polypeptide Vmw110. Journal of General Virology, 2571-2585.
50. Stuurman, N., DeGraaf, A., Josso, A., Humbel, B., DeYong, L. & van Driel, R. (1992). A monoclonal antibody recognising nuclear matrix associated nuclear bodies. Journal of Cell Science 101, 773-784.
51. Towbin, H., Staehelin, T. & Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedures and some applications. Proceedings of the National Academy of Sciences, USA 76, 4350-4354.
52. Virtanen, A. & Pettersson, U. (1985). Organization of early region 1B of human adenovirus type 2: identification of four differentially spliced mRNAs. Journal of Virology 54, 383-391.
53. Weinberg, D. H. & Ketner, G. (1983). A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2. Proceedings of the National Academy of Sciences, USA 80, 5383-5386.
54. Zantema, A., Fransen, J. A. M., Davis-Olivier, A., Ramaekers, F. C. S., Vooijs, G. P., DeLys, B. & van der Eb, A. J. (1985). Localization of the E1B proteins of adenovirus 5 in transformed cells, as revealed by interaction with monoclonal antibodies. Virology 142, 44-58.