Metabolic interactions between ethanol and MDMA in primary cultured rat hepatocytes

Toxicology

Volumn 270, Issue 2-3, 2010, Pages 150-157

  Pontes, Helena ^a   de Pinho, Paula Guedes ^a   Fernandes, Eduarda ^a   Branco, Paula Sério ^b   Ferreira, Luísa Maria ^b   Carmo, Helena ^a   Remião, Fernando ^a   Carvalho, Félix ^a   Bastos, Maria Lourdes ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSIDADE NOVA DE LISBOA   (Portugal)

Author keywords

3,4 Methylenedioxymethamphetamine; Cytochrome P450; Ethanol; Metabolic interactions; Primary cultured rat hepatocytes

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ALCOHOL; ALLYL SULFIDE; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; KETOCONAZOLE; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CHEMICAL INTERACTION; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME INDUCTION; EXPOSURE; GAS CHROMATOGRAPHY; HYPERTHERMIA; INCUBATION TIME; LIVER CELL; MALE; MASS SPECTROMETRY; METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TEMPERATURE DEPENDENCE;

ANIMALS; BIOTRANSFORMATION; CELL DEATH; CELL SEPARATION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 CYP3A; DRUG INTERACTIONS; ETHANOL; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HALLUCINOGENS; HEPATOCYTES; L-LACTATE DEHYDROGENASE; MALE; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; OXIDATION-REDUCTION; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

RATTUS;

EID: 77950020527     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2010.02.010     Document Type: Article

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