-
1
-
-
0024343858
-
Human cytchrome P450PA (P4501A2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines
-
Butler MA, Iwasaki M, Guengerich FP and Kadlubar FF (1989) Human cytchrome P450PA (P4501A2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. Proc Natl Acad Sci USA 86:7696-7700.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7696-7700
-
-
Butler, M.A.1
Iwasaki, M.2
Guengerich, F.P.3
Kadlubar, F.F.4
-
2
-
-
0031940804
-
Effect of common solvents on in vitro cytochrome P450-mediated metabolic activities in human liver microsomes
-
Chauret N, Gauthier A and Nicoll-Griffith DA (1998) Effect of common solvents on in vitro cytochrome P450-mediated metabolic activities in human liver microsomes. Drug Metab Dispos 26:1-4.
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 1-4
-
-
Chauret, N.1
Gauthier, A.2
Nicoll-Griffith, D.A.3
-
3
-
-
0023919384
-
A direct, highly sensitive assay for cytochrome P-450 catalyzed O-deethylation using a novel coumarin analog
-
DeLuca JG, Dysart GR, Rasnick D and Bradley MO (1988) A direct, highly sensitive assay for cytochrome P-450 catalyzed O-deethylation using a novel coumarin analog. Biochem Pharmacol 39:1731-1739.
-
(1988)
Biochem Pharmacol
, vol.39
, pp. 1731-1739
-
-
DeLuca, J.G.1
Dysart, G.R.2
Rasnick, D.3
Bradley, M.O.4
-
4
-
-
0031149716
-
Inhibition of coumarin 7-hydroxylase activity in human liver microsomes
-
Draper AJ, Madan A and Parkinson A (1997) Inhibition of coumarin 7-hydroxylase activity in human liver microsomes. Arch Biochem Biophys 341:47-61.
-
(1997)
Arch Biochem Biophys
, vol.341
, pp. 47-61
-
-
Draper, A.J.1
Madan, A.2
Parkinson, A.3
-
5
-
-
0017847465
-
An improved assay of 7-ethoxycoumarin O-deethylase activity: Induction of hepatic activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorobenzo-p-dioxin
-
Greenlee WF and Poland A (1978) An improved assay of 7-ethoxycoumarin O-deethylase activity: Induction of hepatic activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorobenzo-p-dioxin. J Pharmacol Exp Ther 205: 596-605.
-
(1978)
J Pharmacol Exp Ther
, vol.205
, pp. 596-605
-
-
Greenlee, W.F.1
Poland, A.2
-
6
-
-
0029833258
-
Catalytic role for cytochrome P4502B6 in the N-demethylation of S-mephenytoin
-
Heyn H, White RB and Stevens JC (1996) Catalytic role for cytochrome P4502B6 in the N-demethylation of S-mephenytoin. Drug Metab Dispos 24:948-954.
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 948-954
-
-
Heyn, H.1
White, R.B.2
Stevens, J.C.3
-
7
-
-
0031921010
-
Evaluation of the selectivity of in vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities
-
Hickman D, Wang J-P, Wang Y and Unadkat JD (1998) Evaluation of the selectivity of in vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities. Drug Metab Dispos 26:207-215.
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 207-215
-
-
Hickman, D.1
Wang, J.-P.2
Wang, Y.3
Unadkat, J.D.4
-
8
-
-
0023258883
-
High performance liquid chromatographic assays for bufuralol 1′-hydroxylation, debrisoquine 4-hydroxylation and dextromethorphan O-demethylation in microsomes and purified cytochrome P-450 isozymes of human liver
-
Kronbach T, Mathys D, Gut J, Catin T and Meyer UA (1987) High performance liquid Chromatographic assays for bufuralol 1′-hydroxylation, debrisoquine 4-hydroxylation and dextromethorphan O-demethylation in microsomes and purified cytochrome P-450 isozymes of human liver. Anal Biochem 162:24-32.
-
(1987)
Anal Biochem
, vol.162
, pp. 24-32
-
-
Kronbach, T.1
Mathys, D.2
Gut, J.3
Catin, T.4
Meyer, U.A.5
-
9
-
-
0027264432
-
Cytochrome P450TB (CYP2C): A major monooxy-genase catalyzing diclofenac 4′-hydroxylation in human liver
-
Leeman T, Transon C and Dayer P (1993) Cytochrome P450TB (CYP2C): A major monooxy-genase catalyzing diclofenac 4′-hydroxylation in human liver. Life Sci 52:29-34.
-
(1993)
Life Sci
, vol.52
, pp. 29-34
-
-
Leeman, T.1
Transon, C.2
Dayer, P.3
-
10
-
-
0030848298
-
In vitro identification of the human cytochrome P450 enzymes involved in the metabolism of R( + )- and S( - )-carvedilol
-
Oldham HG and Clarke SE (1977) In vitro identification of the human cytochrome P450 enzymes involved in the metabolism of R( + )- and S( - )-carvedilol. Drug Metab Dispos 25:970-977.
-
(1977)
Drug Metab Dispos
, vol.25
, pp. 970-977
-
-
Oldham, H.G.1
Clarke, S.E.2
-
11
-
-
0028036727
-
Selective biotransformation of taxol to 6α-hydroxytaxol by human cytochrome P450 2C8
-
Rahman A, Korzekwa KR, Grogan J, Gonzalez FJ and Harris JW (1994) Selective biotransformation of Taxol to 6α-hydroxytaxol by human cytochrome P450 2C8. Cancer Res 54:5543-5546.
-
(1994)
Cancer Res
, vol.54
, pp. 5543-5546
-
-
Rahman, A.1
Korzekwa, K.R.2
Grogan, J.3
Gonzalez, F.J.4
Harris, J.W.5
-
12
-
-
0027445449
-
Isolation and characterisation of human liver cytochrome P450 2C19: Correlation between 2C19 and S-mephenytoin 4′-hydroxylase
-
Wrighton SA, Stevens JC, Becker JW and VandenBranden M (1993) Isolation and characterisation of human liver cytochrome P450 2C19: Correlation between 2C19 and S-mephenytoin 4′-hydroxylase. Arch Biochem Biophys 306:240-245.
-
(1993)
Arch Biochem Biophys
, vol.306
, pp. 240-245
-
-
Wrighton, S.A.1
Stevens, J.C.2
Becker, J.W.3
Vandenbranden, M.4
|