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Volumn 27, Issue 2, 1999, Pages 246-249

Effect of methanol, ethanol, dimethyl sulfoxide, and acetonitrile on in vitro activities of cDNA-expressed human cytochromes P-450

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHOXY 4 TRIFLUOROMETHYLCOUMARIN; ACETONITRILE; ALCOHOL; BUFURALOL; COMPLEMENTARY DNA; COUMARIN; COUMARIN DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; CYTOCHROME P450 ISOENZYME; DEBRISOQUINE 4 HYDROXYLASE; DIMETHYL SULFOXIDE; ETHOXYRESORUFIN DEETHYLASE; METHANOL; PACLITAXEL; PHENACETIN; PHENACETIN O DEETHYLASE; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 0345490845     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (270)

References (12)
  • 1
    • 0024343858 scopus 로고
    • Human cytchrome P450PA (P4501A2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines
    • Butler MA, Iwasaki M, Guengerich FP and Kadlubar FF (1989) Human cytchrome P450PA (P4501A2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. Proc Natl Acad Sci USA 86:7696-7700.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7696-7700
    • Butler, M.A.1    Iwasaki, M.2    Guengerich, F.P.3    Kadlubar, F.F.4
  • 2
    • 0031940804 scopus 로고    scopus 로고
    • Effect of common solvents on in vitro cytochrome P450-mediated metabolic activities in human liver microsomes
    • Chauret N, Gauthier A and Nicoll-Griffith DA (1998) Effect of common solvents on in vitro cytochrome P450-mediated metabolic activities in human liver microsomes. Drug Metab Dispos 26:1-4.
    • (1998) Drug Metab Dispos , vol.26 , pp. 1-4
    • Chauret, N.1    Gauthier, A.2    Nicoll-Griffith, D.A.3
  • 3
    • 0023919384 scopus 로고
    • A direct, highly sensitive assay for cytochrome P-450 catalyzed O-deethylation using a novel coumarin analog
    • DeLuca JG, Dysart GR, Rasnick D and Bradley MO (1988) A direct, highly sensitive assay for cytochrome P-450 catalyzed O-deethylation using a novel coumarin analog. Biochem Pharmacol 39:1731-1739.
    • (1988) Biochem Pharmacol , vol.39 , pp. 1731-1739
    • DeLuca, J.G.1    Dysart, G.R.2    Rasnick, D.3    Bradley, M.O.4
  • 4
    • 0031149716 scopus 로고    scopus 로고
    • Inhibition of coumarin 7-hydroxylase activity in human liver microsomes
    • Draper AJ, Madan A and Parkinson A (1997) Inhibition of coumarin 7-hydroxylase activity in human liver microsomes. Arch Biochem Biophys 341:47-61.
    • (1997) Arch Biochem Biophys , vol.341 , pp. 47-61
    • Draper, A.J.1    Madan, A.2    Parkinson, A.3
  • 5
    • 0017847465 scopus 로고
    • An improved assay of 7-ethoxycoumarin O-deethylase activity: Induction of hepatic activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorobenzo-p-dioxin
    • Greenlee WF and Poland A (1978) An improved assay of 7-ethoxycoumarin O-deethylase activity: Induction of hepatic activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorobenzo-p-dioxin. J Pharmacol Exp Ther 205: 596-605.
    • (1978) J Pharmacol Exp Ther , vol.205 , pp. 596-605
    • Greenlee, W.F.1    Poland, A.2
  • 6
    • 0029833258 scopus 로고    scopus 로고
    • Catalytic role for cytochrome P4502B6 in the N-demethylation of S-mephenytoin
    • Heyn H, White RB and Stevens JC (1996) Catalytic role for cytochrome P4502B6 in the N-demethylation of S-mephenytoin. Drug Metab Dispos 24:948-954.
    • (1996) Drug Metab Dispos , vol.24 , pp. 948-954
    • Heyn, H.1    White, R.B.2    Stevens, J.C.3
  • 7
    • 0031921010 scopus 로고    scopus 로고
    • Evaluation of the selectivity of in vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities
    • Hickman D, Wang J-P, Wang Y and Unadkat JD (1998) Evaluation of the selectivity of in vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities. Drug Metab Dispos 26:207-215.
    • (1998) Drug Metab Dispos , vol.26 , pp. 207-215
    • Hickman, D.1    Wang, J.-P.2    Wang, Y.3    Unadkat, J.D.4
  • 8
    • 0023258883 scopus 로고
    • High performance liquid chromatographic assays for bufuralol 1′-hydroxylation, debrisoquine 4-hydroxylation and dextromethorphan O-demethylation in microsomes and purified cytochrome P-450 isozymes of human liver
    • Kronbach T, Mathys D, Gut J, Catin T and Meyer UA (1987) High performance liquid Chromatographic assays for bufuralol 1′-hydroxylation, debrisoquine 4-hydroxylation and dextromethorphan O-demethylation in microsomes and purified cytochrome P-450 isozymes of human liver. Anal Biochem 162:24-32.
    • (1987) Anal Biochem , vol.162 , pp. 24-32
    • Kronbach, T.1    Mathys, D.2    Gut, J.3    Catin, T.4    Meyer, U.A.5
  • 9
    • 0027264432 scopus 로고
    • Cytochrome P450TB (CYP2C): A major monooxy-genase catalyzing diclofenac 4′-hydroxylation in human liver
    • Leeman T, Transon C and Dayer P (1993) Cytochrome P450TB (CYP2C): A major monooxy-genase catalyzing diclofenac 4′-hydroxylation in human liver. Life Sci 52:29-34.
    • (1993) Life Sci , vol.52 , pp. 29-34
    • Leeman, T.1    Transon, C.2    Dayer, P.3
  • 10
    • 0030848298 scopus 로고
    • In vitro identification of the human cytochrome P450 enzymes involved in the metabolism of R( + )- and S( - )-carvedilol
    • Oldham HG and Clarke SE (1977) In vitro identification of the human cytochrome P450 enzymes involved in the metabolism of R( + )- and S( - )-carvedilol. Drug Metab Dispos 25:970-977.
    • (1977) Drug Metab Dispos , vol.25 , pp. 970-977
    • Oldham, H.G.1    Clarke, S.E.2
  • 11
    • 0028036727 scopus 로고
    • Selective biotransformation of taxol to 6α-hydroxytaxol by human cytochrome P450 2C8
    • Rahman A, Korzekwa KR, Grogan J, Gonzalez FJ and Harris JW (1994) Selective biotransformation of Taxol to 6α-hydroxytaxol by human cytochrome P450 2C8. Cancer Res 54:5543-5546.
    • (1994) Cancer Res , vol.54 , pp. 5543-5546
    • Rahman, A.1    Korzekwa, K.R.2    Grogan, J.3    Gonzalez, F.J.4    Harris, J.W.5
  • 12
    • 0027445449 scopus 로고
    • Isolation and characterisation of human liver cytochrome P450 2C19: Correlation between 2C19 and S-mephenytoin 4′-hydroxylase
    • Wrighton SA, Stevens JC, Becker JW and VandenBranden M (1993) Isolation and characterisation of human liver cytochrome P450 2C19: Correlation between 2C19 and S-mephenytoin 4′-hydroxylase. Arch Biochem Biophys 306:240-245.
    • (1993) Arch Biochem Biophys , vol.306 , pp. 240-245
    • Wrighton, S.A.1    Stevens, J.C.2    Becker, J.W.3    Vandenbranden, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.