Beta sheet 2-alpha helix C loop of cytochrome P450 reductase serves as a docking site for redox partners

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1804, Issue 6, 2010, Pages 1285-1293

  Jang, Hyun Hee ^a   Jamakhandi, Arvind P ^b   Sullivan, Shane Z ^b   Yun, Chul Ho ^a   Hollenberg, Paul F ^c   Miller, Grover P ^b  

^a Chonnam National University   (South Korea)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

CYP2B1; Cytochrome P450 reductase; Docking; Electrostatic interactions; Protein protein interactions; Site directed mutagenesis

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALANINE; CYTOCHROME C; CYTOCHROME P450 2B1; CYTOCHROME P450 REDUCTASE;

ALPHA HELIX; ARTICLE; BETA SHEET; CATALYSIS; CONTROLLED STUDY; DISSOCIATION CONSTANT; ELECTRICITY; ELECTRON; ELECTRON TRANSPORT; IONIC STRENGTH; MOLECULAR DOCKING; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; STEADY STATE; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; CATALYSIS; CATTLE; CYTOCHROME P-450 CYP2B1; CYTOCHROMES C; HORSES; MODELS, MOLECULAR; MUTATION, MISSENSE; NADPH-FERRIHEMOPROTEIN REDUCTASE; OSMOLAR CONCENTRATION; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; STATIC ELECTRICITY;

TRIFLUORO;

EID: 77949915933     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2010.02.003     Document Type: Article

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