Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis

Blood

Volumn 115, Issue 8, 2010, Pages 1610-1620

  Jacob, Bindya ^a,b   Osato, Motomi ^a,b   Yamashita, Namiko ^a   Wang, Chelsia Qiuxia ^a   Taniuchi, Ichiro ^c   Littman, Dan R ^d   Asou, Norio ^e   Ito, Yoshiaki ^a,b  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c RIKEN Center for Integrative Medical Sciences   (Japan)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EVI5 PROTEIN; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; EVI5 PROTEIN, HUMAN; EVI5 PROTEIN, MOUSE; NUCLEAR PROTEIN; RUNX1 PROTEIN, HUMAN; RUNX1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL EXPERIMENT; ARTICLE; BLAST CELL CRISIS; BONE MARROW TRANSPLANTATION; C57BL 6 MOUSE; CELL STRESS; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; EXON; FLOW CYTOMETRY; GENE INSERTION; GENE OVEREXPRESSION; GENETIC SCREENING; HEMATOPOIETIC STEM CELL; HUMAN; IN VITRO STUDY; LEUKEMOGENESIS; MOUSE; MUTAGENESIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; RETROVIRUS; TARGET CELL; TRANSGENIC MOUSE; ANIMAL; CELL TRANSFORMATION; GENETICS; LEUKEMIA; METABOLISM; MOUSE MUTANT; PATHOLOGY;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CORE BINDING FACTOR ALPHA 2 SUBUNIT; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS; TRANSCRIPTION FACTORS;

EID: 77949888952     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-07-232249     Document Type: Article

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