Structural investigation of the binding of 5-substituted swainsonine analogues to golgi α-mannosidase II

ChemBioChem

Volumn 11, Issue 5, 2010, Pages 673-680

  Kuntz, Douglas A ^a   Nakayama, Shinichi ^b   Shea, Kayla ^a   Hori, Hitoshi ^b   Uto, Yoshihiro ^b   Nagasawa, Hideko ^b,c   Rose, David R ^a,d  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^d UNIVERSITY OF WATERLOO   (Canada)

Author keywords

Antitumor agents; Aza sugar; Glycosidases; Inhibitors; X ray diffraction

Indexed keywords

ALPHA MANNOSIDASE; CARBONYL DERIVATIVE; GOLGI ALPHA MANNOSIDASE II; SWAINSONINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; IC 50; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTINEOPLASTIC AGENTS; BINDING SITES; CATALYTIC DOMAIN; DROSOPHILA MELANOGASTER; GOLGI APPARATUS; MANNOSIDASES; PROTEIN BINDING; SWAINSONINE;

EID: 77949840396     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200900750     Document Type: Article

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