Energy expenditure of calorically restricted rats is higher than predicted from their altered body composition

Mechanisms of Ageing and Development

Volumn 126, Issue 6-7, 2005, Pages 783-793

  Selman, Colin ^a,d   Phillips, Tracey ^a   Staib, Jessica L ^a   Duncan, Jackie S ^c   Leeuwenburgh, Christiaan ^a   Speakman, John R ^b,c  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c ROWETT RESEARCH INSTITUTE   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Aging; Caloric restriction; Doubly labeled water; Metabolic rate; Organ morphometrics

Indexed keywords

AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CALORIC INTAKE; CALORIC RESTRICTION; CONTROLLED STUDY; ENERGY EXPENDITURE; MALE; MULTIPLE REGRESSION; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RAT; STATISTICAL MODEL;

ANIMALS; BODY CONSTITUTION; CALORIC RESTRICTION; ENERGY METABOLISM; LONGEVITY; MALE; RATS; RATS, INBRED F344;

ANIMALIA;

EID: 18944391216     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2005.02.004     Document Type: Article

References (60)

1. G. Barja Endogenous oxidative stress: relationship to aging, longevity and caloric restriction Ageing Res. Rev. 1 2002 397 411
2. G. Barja Rate of generation of oxidative stress-related damage and animal longevity Free Radic. Biol. Med. 33 2002 1167 1172
3. K.B. Beckman, and B.N. Ames The free radical theory of aging matures Physiol. Rev. 78 1998 547 581
4. B.J. Black Jr., C.A. McMahan, E.J. Masoro, Y. Ikeno, and M.S. Katz Senescent terminal weight loss in the male F344 rat Am. J. Physiol. Regul. Integr. Comp. Physiol. 284 2003 R336 R342
5. S. Blanc, D. Schoeller, J. Kemnitz, R. Weindruch, R. Colman, W. Newton, K. Wink, S. Baum, and J. Ramsey Energy expenditure of rhesus monkeys subjected to 11 years of dietary restriction J. Clin. Endocrinol. Metab. 88 2003 16 23
6. C.A. Blanton, B.A. Horwitz, C. Murtagh-Mark, D.W. Gietzen, S.M. Griffey, and R.B. McDonald Meal patterns associated with the age-related decline in food intake in the Fischer 344 rat Am. J. Physiol. 275 1998 R1494 R1502
7. B.P. Braeckman, K. Houthoofd, and J.R. Vanfleteren Rebuttle to van Voorhies: the influence of metabolic rate on longevity in the nematode Caenorhabditis elegans Aging Cell 1 2002 89 90
8. M.D. Brand Uncoupling to survive? The role of mitochondrial inefficiency in ageing Exp. Gerontol. 35 2000 811 820
9. P. Chomczynski, and N. Sacchi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal. Biochem. 162 1987 156 159
10. J.D. Coppola, B.A. Horwitz, J. Hamilton, and R.B. McDonald Expression of NPY Yl and Y5 receptors in the hypothalamic paraventricular nucleus of aged Fischer 344 rats Am. J. Physiol. Regul. Integr. Comp. Physiol. 287 2004 R69 R75
11. J.P. DeLany, B.C. Hansen, N.L. Bodkin, J. Hannah, and G.A. Bray Long-term calorie restriction reduces energy expenditure in aging monkeys J. Gerontol. A Biol. Sci. Med. Sci. 54 1999 B5 B11 (discussion B12-13)
12. P.H. Duffy, R.J. Feuers, J.A. Leakey, K. Nakamura, A. Turturro, and R.W. Hart Effect of chronic caloric restriction on physiological variables related to energy metabolism in the male Fischer 344 rat Mech. Ageing Dev. 48 1989 117 133
13. P.C. Even, V. Rolland, S. Roseau, J.C. Bouthegourd, and D. Tome Prediction of basal metabolism from organ size in the rat: relationship to strain, feeding, age, and obesity Am. J. Physiol. 280 2001 R1887 R1896
14. K. Flurkey, J. Papaconstantinou, and D.E. Harrison The Snell dwarf mutation Pitl (dw) can increase lifespan in mice Mech. Ageing Dev. 123 2002 121 130
15. R. Gredilla, A. Sanz, M. Lopez-Torres, and G. Barja Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart FASEB J. 15 2001 1589 1591
16. J.A. Greenberg Organ metabolic rates and aging: two hypothesis Med. Hypotheses 52 1999 15 22
17. J.A. Greenberg, and C.N. Boozer Metabolic mass, metabolic rate, caloric restriction, and aging in male Fischer 344 rats Mech. Ageing Dev. 113 2000 37 48
18. J.A. Greenberg, H. Wei, K. Ward, and C.N. Boozer Whole-body metabolic rate appears to determine the rate of DNA oxidative damage and glycation involved in aging Mech. Ageing Dev. 115 2000 107 117
19. D. Harman Aging: a theory based on free radical and radiation chemistry J. Gerontol. 11 1956 298 300
20. D. Harman Prolongation of life: role of free radical reactions in aging J. Am. Geriatr. Soc. 17 1969 721 735
21. J.O. Holloszy, and E.K. Smith Effects of exercise on longevity of rats Fed. Proc. 46 1987 1850 1853
22. B.A. Horwitz, C.A. Blanton, and R.B. McDonald Physiologic determinants of the anorexia of aging: insights from animal studies Annu. Rev. Nutr. 22 2002 417 438
23. H.A. Krebs Body size and tissue respiration Biochem. Biophys. Acta 4 1950 249 269
24. A.J. Lambert, and B.J. Merry Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: reversal by insulin Am. J. Physiol. Regul. Integr. Comp. Physiol. 286 2004 R71 R79
25. A.J. Lambert, B. Wang, J. Yardley, J. Edwards, and B.J. Merry The effect of aging and caloric restriction on mitochondrial protein density and oxygen consumption Exp. Gerontol. 39 2004 289 295
26. S.J. Lin, M. Kaeberlein, A.A. Andalis, L.A. Sturtz, P.A. Defossez, V.C. Culotta, G.R. Fink, and L. Guarente Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration Nature 418 2002 344 348
27. H. Maeda, C.A. Gleiser, E.J. Masoro, I. Murata, C.A. McMahan, and B.P. Yu Nutritional influences on aging of Fischer 344 rats: II Pathol. J. Gerontol. 40 1985 671 688
28. E.J. Masoro Antiaging action of caloric restriction: endocrine and metabolic aspects Obes. Res. 3 1995 241S 247S
29. E.J. Masoro Caloric restriction and aging: an update Exp. Gerontol. 35 2000 299 305
30. Masoro, E.J., 2003. Subfield history: caloric restriction, slowing aging, and extending life. Sci. Aging Knowl. Environ. 2003 (8), RE2.
31. E.J. Masoro, B.P. Yu, and H.A. Bertrand Action of food restriction in delaying the aging process Proc. Natl. Acad. Sci. USA 79 1982 4239 4241
32. R. McCarter, E.J. Masoro, and B.P. Yu Does food restriction retard aging by reducing the metabolic rate? Am. J. Physiol. 248 1985 E488 E490
33. R.J. McCarter, and J. Palmer Energy metabolism and aging: a lifelong study of Fischer 344 rats Am. J. Physiol. 263 1992 E448 E452
34. B.J. Merry Molecular mechanisms linking calorie restriction and longevity Int. J. Biochem. Cell Biol. 34 2002 1340 1354
35. D.G. Nicholls Mitochondrial membrane potential and aging Aging Cell 3 2004 35 40
36. G.C. Packard, and T.J. Boardman The misuse of ratios, indices, and percentages in ecophysiological research Physiol. Zool. 61 1988 1 9
37. G.C. Packard, and T.J. Boardman The use of percentages and size-specific indices to normalise physiological data for variation in body size: wasted time, wasted effort Comp. Biochem. Physiol. A 122 1999 37 44
38. R.L. Pearl The Rate of Living 1928 Alfred Knopf New York
39. E.T. Poehlman Editorial: reduced metabolic rate after caloric restriction - Can we agree on how to normalise the data? J. Clin. Endocrinol. Metab. 88 2003 14 15
40. J.J. Ramsey, M.E. Harper, and R. Weindruch Restriction of energy intake, energy expenditure, and aging Free Radic. Biol. Med. 29 2000 946 968
41. J.J. Ramsey, E.B. Roecker, R. Weindruch, and J.W. Kemnitz Energy expenditure of adult male rhesus monkeys during the first 30 mo of dietary restriction Am. J. Physiol. 272 1997 E901 E907
42. M. Rubner Das Problem der Lebensdauer und Seine Beziehungen zum Wachstum und Ernahrung 1908 Oldenbourg Munchen
43. G.A. Sacher Life table modification and life prolongation C.E. Finch L. Hayflick Handbook of the Biology of Aging 1977 Van Nostrand Reinhold New York pp. 582-638
44. C. Selman, T. Grune, A. Stolzing, M. Jakstadt, J.S. McLaren, and J.R. Speakman The consequences of acute cold exposure on protein oxidation and proteasome activity in short-tailed field voles, microtus agrestis Free Radic. Biol. Med. 33 2002 259 265
45. C. Selman, S. Kendaiah, R. Gredilla, and C. Leeuwenburgh Increased hepatic apoptosis during short-term caloric restriction is not associated with an enhancement in caspase levels Exp. Gerontol. 38 2003 897 903
46. J.R. Speakman Doubly labelled water. Theory and Practice 1997 Chapman and Hall London
47. J.R. Speakman The history and theory of the doubly labeled water technique Am. J. Clin. Nutr. 68 1998 932S 938S
48. J.R. Speakman The cost of living: field metabolic rates of small mammals Adv. Ecol. Res. 30 2000 177 297
49. J.R. Speakman Oxidative phosphorylation, mitochondrial proton cycling, free-radical production and aging Energy Metabolism and Lifespan Determination 2004 Elsevier Amsterdam pp. 35-68
50. J.R. Speakman, C. Selman, J.S. McLaren, and E.J. Harper Living fast, dying when? The link between aging and energetics J. Nutr. 132 2002 1583S 1597S
51. J.R. Speakman, D.A. Talbot, C. Selman, S. Snart, J.S. McLaren, P. Redman, E. Krol, D.M. Jackson, M.S. Johnson, and M.D. Brand Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer Aging Cell 3 2004 87 95
52. J.R. Speakman, A. Van Acker, and E.J. Harper Age-related changes in the metabolism and body composition of three dog breeds and their relationship to life expectancy Aging Cell 2 2003 265 275
53. R. Tocco-Bradley, R. Singer, M.J. Kluger, and C.A. Kauffman Effect of age on the febrile response of rats to endogenous pyrogen Gerontology 31 1985 349 354
54. P. Trayhurn, T. M.E., J.S. Duncan, D. Black, J.H. Beattie, and D.V. Rayner Ultra-rapid detection of mRNAs on northern blots with digoxigenin-labelled oligonucleotides and 'CDP-Star', a new chemiluminescence substrate Biochem. Soc. Trans. 23 1995 494S
55. A. Turturro, W.W. Witt, S. Lewis, B.S. Hass, R.D. Lipman, and R.W. Hart Growth curves and survival characteristics of the animals used in the biomarkers of aging program J. Gerontol. A Biol. Sci. Med. Sci. 54 1999 B492 B501
56. W.A. Van Voorhies Metabolism and lifespan Exp. Gerontol. 36 2001 55 64
57. W.A. Van Voorhies The influence of metabolic rate on longevity in the nematode Caenorhabditis elegans Aging Cell 1 2002 91 101
58. W.A. Van Voorhies Rebuttle to Braeckman et al. assessing metabolic activity in aging Caenorhabditis elegans: concepts and controversies Aging Cell 1 2002 102 103
59. W.A. Van Voorhies, and S. Ward Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate Proc. Natl. Acad. Sci. USA 96 1999 11399 11403
60. B.P. Yu, E.J. Masoro, and C.A. McMahan Nutritional influences on aging of Fischer 344 rats: I. Physical, metabolic, and longevity characteristics J. Gerontol. 40 1985 657 670