3-Methylcholanthrene elicits DNA adduct formation in the CYP1A1 promoter region and attenuates reporter gene expression in rat H4IIE cells

Biochemical and Biophysical Research Communications

Volumn 354, Issue 4, 2007, Pages 1071-1077

  Moorthy, Bhagavatula ^a   Muthiah, Kathirvel ^a   Fazili, Inayat S ^a   Kondraganti, Sudha R ^a   Wang, Lihua ^a   Couroucli, Xanthi I ^a   Jiang, Weiwu ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

3 Methylcholanthrene; 32P Postlabeling; Ah receptor; CYP1A1; DNA adducts; Gene regulation; Sequence specific; Transient transfections

Indexed keywords

3 METHYLCHOLANTHRENE; CYTOCHROME P450 1A1; LUCIFERASE; PLASMID DNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; COVALENT BOND; DNA ADDUCT; FEMALE; GENE EXPRESSION; GENE SEQUENCE; HEPATOMA CELL; HYPOTHESIS; LIVER MICROSOME; MODULATION; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; RAT; REPORTER GENE; TEMPERATURE; TRANSIENT TRANSFECTION; WILD TYPE;

ANIMALS; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; DNA ADDUCTS; ENZYME INDUCTION; FEMALE; GENE EXPRESSION; GENES, REPORTER; HUMANS; LIVER NEOPLASMS, EXPERIMENTAL; MALE; METHYLCHOLANTHRENE; MICE; MICE, KNOCKOUT; MICROSOMES, LIVER; MODELS, BIOLOGICAL; PROMOTER REGIONS (GENETICS); RATS; TRANSFECTION;

RATTUS;

EID: 33846862477     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.01.103     Document Type: Article

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