메뉴 건너뛰기




Volumn 34, Issue 3, 2010, Pages 557-568

FAAH deficiency promotes energy storage and enhances the motivation for food

Author keywords

Anandamide; Body weight; Fatty acid amide hydrolase; Food intake; Lipid turnover; Oleoylethanolamide

Indexed keywords

ADIPONECTIN; ANANDAMIDE; FATTY ACID AMIDASE; LEPTIN; N OLEOYLETHANOLAMINE; RIMONABANT; TRIACYLGLYCEROL; AMIDASE; AMIDE; ARACHIDONIC ACID DERIVATIVE; CANNABINOID RECEPTOR AFFECTING AGENT; ENDOCANNABINOID; FAT INTAKE; FATTY-ACID AMIDE HYDROLASE; OLEIC ACID; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE;

EID: 77949542479     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2009.262     Document Type: Article
Times cited : (74)

References (39)
  • 1
    • 35548953757 scopus 로고    scopus 로고
    • CB1 receptors: Emerging evidence for central and peripheral mechanisms that regulate energy balance, metabolism, and cardiovascular health
    • Cota D. CB1 receptors: emerging evidence for central and peripheral mechanisms that regulate energy balance, metabolism, and cardiovascular health. Diabetes Metab Res Rev 2007; 23: 507-517.
    • (2007) Diabetes Metab Res Rev , vol.23 , pp. 507-517
    • Cota, D.1
  • 2
    • 0032541111 scopus 로고    scopus 로고
    • Appetite suppression and weight loss after the cannabinoid antagonist SR 141716
    • Colombo G, Agabio R, Díaz G, Lobina C, Reali R, Gessa GL. Appetite suppression and weight loss after the cannabinoid antagonist SR 141716. Life Sci 1998; 63: L113-L117.
    • (1998) Life Sci , vol.63
    • Colombo, G.1    Agabio, R.2    Díaz, G.3    Lobina, C.4    Reali, R.5    Gessa, G.L.6
  • 3
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
    • Van Gaal LF, Rissanen AM, Scheen AJ, Ziegler O, Rossner S. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 2005; 365: 1389-1397.
    • (2005) Lancet , vol.365 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3    Ziegler, O.4    Rossner, S.5
  • 4
    • 85047690626 scopus 로고    scopus 로고
    • The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
    • Cota D, Marsicano G, Tschop M, Grubler Y, Flachskamm C, Schubert M et al. The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 2003; 112: 423-431.
    • (2003) J Clin Invest , vol.112 , pp. 423-431
    • Cota, D.1    Marsicano, G.2    Tschop, M.3    Grubler, Y.4    Flachskamm, C.5    Schubert, M.6
  • 5
    • 0035185205 scopus 로고    scopus 로고
    • Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats
    • Jamshidi N, Taylor DA. Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. Br J Pharmacol 200; 134: 1151-1154.
    • Br J Pharmacol , vol.200 , Issue.134 , pp. 1151-1154
    • Jamshidi, N.1    Taylor, D.A.2
  • 6
    • 0035984946 scopus 로고    scopus 로고
    • Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: Stimulation of eating by 2-arachidonoyl glycerol
    • Kirkham TC, Williams CM, Fezza F, Di Marzo V. Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. Br J Pharmacol 2002; 136: 550-557.
    • (2002) Br J Pharmacol , vol.136 , pp. 550-557
    • Kirkham, T.C.1    Williams, C.M.2    Fezza, F.3    Di Marzo, V.4
  • 7
    • 17644367480 scopus 로고    scopus 로고
    • The cannabinoid CB1 receptor antagonist SR141716A reduces appetitive and consum-matory responses for food
    • Thornton-Jones ZD, Vickers SP, Clifton PG. The cannabinoid CB1 receptor antagonist SR141716A reduces appetitive and consum-matory responses for food. Psychopharmacology (Berl) 2005; 179: 452-460.
    • (2005) Psychopharmacology (Berl) , vol.179 , pp. 452-460
    • Thornton-Jones, Z.D.1    Vickers, S.P.2    Clifton, P.G.3
  • 8
    • 1642298863 scopus 로고    scopus 로고
    • Expression of cannabinoid CB1 receptors by vagal afferent neurons is inhibited by cholecystokinin
    • Burdyga G, Lal S, Varro A, Dimaline R, Thompson DG, Dockray GJ. Expression of cannabinoid CB1 receptors by vagal afferent neurons is inhibited by cholecystokinin. J Neurosci 2004; 24: 2708-2715.
    • (2004) J Neurosci , vol.24 , pp. 2708-2715
    • Burdyga, G.1    Lal, S.2    Varro, A.3    Dimaline, R.4    Thompson, D.G.5    Dockray, G.J.6
  • 9
    • 0035010955 scopus 로고    scopus 로고
    • Cannabinoids and the gastrointestinal tract
    • Pertwee RG. Cannabinoids and the gastrointestinal tract. Gut 2001; 48: 859-867.
    • (2001) Gut , vol.48 , pp. 859-867
    • Pertwee, R.G.1
  • 10
    • 0037374766 scopus 로고    scopus 로고
    • The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells
    • Bensaid M, Gary-Bobo M, Esclangon A, Maffrand JP, Le FG, Oury-Donat F et al. The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells. Mol Pharmacol 2003; 63: 908-914.
    • (2003) Mol Pharmacol , vol.63 , pp. 908-914
    • Bensaid, M.1    Gary-Bobo, M.2    Esclangon, A.3    Maffrand, J.P.4    Le Fg Oury-Donat, F.5
  • 11
    • 20944436157 scopus 로고    scopus 로고
    • Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
    • Osei-Hyiaman D, DePetrillo M, Pacher P, Liu J, Radaeva S, Batkai S et al. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest 2005; 115: 1298-1305.
    • (2005) J Clin Invest , vol.115 , pp. 1298-1305
    • Osei-Hyiaman, D.1    Depetrillo, M.2    Pacher, P.3    Liu, J.4    Radaeva, S.5    Batkai, S.6
  • 12
    • 0032936642 scopus 로고    scopus 로고
    • Anandamide induces overeating: Mediation by central cannabinoid (CB1) receptors
    • Williams CM, Kirkham TC. Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors. Psycho-pharmacology (Berl) 1999; 143: 315-317.
    • (1999) Psycho-pharmacology (Berl) , vol.143 , pp. 315-317
    • Williams, C.M.1    Kirkham, T.C.2
  • 13
    • 35348864420 scopus 로고    scopus 로고
    • Endocannabinoid hedonic hotspot for sensory pleasure: Anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward
    • Mahler SV, Smith KS, Berridge KC. Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward. Neuropsychopharmaco-logy 2007; 32: 2267-2278.
    • (2007) Neuropsychopharmaco-logy , vol.32 , pp. 2267-2278
    • Mahler, S.V.1    Smith, K.S.2    Berridge, K.C.3
  • 14
  • 15
    • 0034000093 scopus 로고    scopus 로고
    • Anandamide amidohydrolase (fatty acid amide hydrolase)
    • Ueda N, Yamamoto S. Anandamide amidohydrolase (fatty acid amide hydrolase). Prostaglandins Other Lipid Mediat 2000; 61: 19-28.
    • (2000) Prostaglandins Other Lipid Mediat , vol.61 , pp. 19-28
    • Ueda, N.1    Yamamoto, S.2
  • 16
    • 33847734027 scopus 로고    scopus 로고
    • Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine
    • Fu J, Astarita G, Gaetani S, Kim J, Cravatt BF, Mackie K et al. Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine. J Biol Chem 2007; 282: 1518-1528.
    • (2007) J Biol Chem , vol.282 , pp. 1518-1528
    • Fu, J.1    Astarita, G.2    Gaetani, S.3    Kim, J.4    Cravatt, B.F.5    MacKie, K.6
  • 18
    • 3142583174 scopus 로고    scopus 로고
    • Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha)
    • Guzman M, Lo VJ, Fu J, Oveisi F, Blazquez C, Piomelli D. Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha). J Biol Chem 2004; 279: 27849-27854.
    • (2004) J Biol Chem , vol.279 , pp. 27849-27854
    • Guzman, M.1    Lo, V.J.2    Fu, J.3    Oveisi, F.4    Blazquez, C.5    Piomelli, D.6
  • 20
    • 0035979244 scopus 로고    scopus 로고
    • Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
    • Cravatt BF, Demarest K, Patricelli MP, Bracey MH, Giang DK, Martin BR et al. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proc Natl Acad Sci USA 2001; 98: 9371-9376.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9371-9376
    • Cravatt, B.F.1    Demarest, K.2    Patricelli, M.P.3    Bracey, M.H.4    Giang, D.K.5    Martin, B.R.6
  • 21
    • 0042924150 scopus 로고    scopus 로고
    • Modulation of meal pattern in the rat by the anorexic lipid mediator oleoylethanolamide
    • Gaetani S, Oveisi F, Piomelli D. Modulation of meal pattern in the rat by the anorexic lipid mediator oleoylethanolamide. Neuro-psychopharmacology 2003; 28: 1311-1316.
    • (2003) Neuro-psychopharmacology , vol.28 , pp. 1311-1316
    • Gaetani, S.1    Oveisi, F.2    Piomelli, D.3
  • 23
    • 15744385109 scopus 로고    scopus 로고
    • Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3-carbamoyl-biphenyl-3-yl ester (URB597): Effects on anandamide and oleoylethanolamide deactivation
    • Fegley D, Gaetani S, Duranti A, Tontini A, Mor M, Tarzia G et al. Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. J Pharmacol Exp Ther 2005; 313: 352-358.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 352-358
    • Fegley, D.1    Gaetani, S.2    Duranti, A.3    Tontini, A.4    Mor, M.5    Tarzia, G.6
  • 24
    • 43049094858 scopus 로고    scopus 로고
    • Role of the endocannabinoid system in energy balance regulation and obesity
    • Cota D. Role of the endocannabinoid system in energy balance regulation and obesity. Front Horm Res 2008; 36: 135-145.
    • (2008) Front Horm Res , vol.36 , pp. 135-145
    • Cota, D.1
  • 25
    • 0041321275 scopus 로고    scopus 로고
    • Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha
    • Fu J, Gaetani S, Oveisi F, Lo VJ, Serrano A, Rodríguez de Fonseca F et al. Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha. Nature 2003; 425: 90-93.
    • (2003) Nature , vol.425 , pp. 90-93
    • Fu, J.1    Gaetani, S.2    Oveisi, F.3    Lo, V.J.4    Serrano, A.5    Rodríguez De Fonseca, F.6
  • 27
    • 33645517680 scopus 로고    scopus 로고
    • Endogenous cannabinoids in the brain and peripheral tissues: Regulation of their levels and control of food intake
    • Matias I, Bisogno T, Di Marzo V. Endogenous cannabinoids in the brain and peripheral tissues: regulation of their levels and control of food intake. Int J Obes (Lond) 2006; 30 (Suppl 1): S7-S12.
    • (2006) Int J Obes (Lond) , vol.30 , Issue.SUPPL. 1
    • Matias, I.1    Bisogno, T.2    Di Marzo, V.3
  • 29
    • 2442436437 scopus 로고    scopus 로고
    • Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain
    • Valenti M, Vigano D, Casico MG, Rubino T, Steardo L, Parolaro D et al. Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain. Cell Mol Life Sci 2004; 61: 945-950.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 945-950
    • Valenti, M.1    Vigano, D.2    Casico, M.G.3    Rubino, T.4    Steardo, L.5    Parolaro, D.6
  • 30
    • 23944487985 scopus 로고    scopus 로고
    • Cannabinoids augment the release of neuropeptide y in the rat hypothalamus
    • Gamber KM, Macarthur H, Westfall TC. Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus. Neuro-pharmacology 2005; 49: 646-652.
    • (2005) Neuro-pharmacology , vol.49 , pp. 646-652
    • Gamber, K.M.1    MacArthur, H.2    Westfall, T.C.3
  • 31
    • 34247895688 scopus 로고    scopus 로고
    • Cannabinoids excite hypothalamic melanin-concentrating hormone but inhibit hypocretin/orexin neurons: Implications for cannabinoid actions on food intake and cognitive arousal
    • Huang H, cuna-Goycolea C, Li Y, Cheng HM, Obrietan K, van den Pol AN. Cannabinoids excite hypothalamic melanin-concentrating hormone but inhibit hypocretin/orexin neurons: implications for cannabinoid actions on food intake and cognitive arousal. J Neurosci 2007; 27: 4870-4881.
    • (2007) J Neurosci , vol.27 , pp. 4870-4881
    • Huang, H.1    Cuna-Goycolea, C.2    Li, Y.3    Cheng, H.M.4    Obrietan, K.5    Van Den Pol, A.N.6
  • 33
    • 1842866963 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity
    • Ravinet TC, Delgorge C, Menet C, Arnone M, Soubrie P. CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity. Int J Obes Relat Metab Disord 2004; 28: 640-648.
    • (2004) Int J Obes Relat Metab Disord , vol.28 , pp. 640-648
    • Ravinet, T.C.1    Delgorge, C.2    Menet, C.3    Arnone, M.4    Soubrie, P.5
  • 34
    • 33644652183 scopus 로고    scopus 로고
    • Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis
    • Lefebvre P, Chinetti G, Fruchart JC, Staels B. Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis. J Clin Invest 2006; 116: 571-580.
    • (2006) J Clin Invest , vol.116 , pp. 571-580
    • Lefebvre, P.1    Chinetti, G.2    Fruchart, J.C.3    Staels, B.4
  • 35
    • 35748940300 scopus 로고    scopus 로고
    • Role and regulation of acylethanolamides in energy balance: Focus on adipocytes and beta-cells
    • Matias I, Gonthier MP, Petrosino S, Docimo L, Capasso R, Hoareau L et al. Role and regulation of acylethanolamides in energy balance: focus on adipocytes and beta-cells. Br J Pharmacol 2007; 152: 676-690.
    • (2007) Br J Pharmacol , vol.152 , pp. 676-690
    • Matias, I.1    Gonthier, M.P.2    Petrosino, S.3    Docimo, L.4    Capasso, R.5    Hoareau, L.6
  • 36
    • 26044473133 scopus 로고    scopus 로고
    • The role of CB1 receptors in sweet versus fat reinforcement: Effect of CB1 receptor deletion, CB1 receptor antagonism (SR141716A) and CB1 receptor agonism (CP-55940)
    • Ward SJ, Dykstra LA. The role of CB1 receptors in sweet versus fat reinforcement: effect of CB1 receptor deletion, CB1 receptor antagonism (SR141716A) and CB1 receptor agonism (CP-55940). Behav Pharmacol 2005; 16: 381-388.
    • (2005) Behav Pharmacol , vol.16 , pp. 381-388
    • Ward, S.J.1    Dykstra, L.A.2
  • 37
    • 29744460503 scopus 로고    scopus 로고
    • Subcellular localization of type 1 cannabinoid receptors in the rat basal ganglia
    • Matyas F, Yanovsky Y, Mackie K, Kelsch W, Misgeld U, Freund TF. Subcellular localization of type 1 cannabinoid receptors in the rat basal ganglia. Neuroscience 2006; 137: 337-361.
    • (2006) Neuroscience , vol.137 , pp. 337-361
    • Matyas, F.1    Yanovsky, Y.2    MacKie, K.3    Kelsch, W.4    Misgeld, U.5    Freund, T.F.6
  • 38
    • 50649083750 scopus 로고    scopus 로고
    • Targeted enhancement of oleoylethanolamide production in proximal small intestine induces across-meal satiety in rats
    • Fu J, Kim J, Oveisi F, Astarita G, Piomelli D. Targeted enhancement of oleoylethanolamide production in proximal small intestine induces across-meal satiety in rats. Am J Physiol Regul Integr Comp Physiol 2008; 295: R45-R50.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.295
    • Fu, J.1    Kim, J.2    Oveisi, F.3    Astarita, G.4    Piomelli, D.5
  • 39
    • 44749085444 scopus 로고    scopus 로고
    • TRPV1-null mice are protected from diet-induced obesity
    • Motter AL, Ahern GP. TRPV1-null mice are protected from diet-induced obesity. FEBS Lett 2008; 582: 2257-2262.
    • (2008) FEBS Lett , vol.582 , pp. 2257-2262
    • Motter, A.L.1    Ahern, G.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.