Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles

PLoS ONE

Volumn 4, Issue 12, 2009, Pages

  Huang, Tao ^c,d   Cui, Weiren ^a,b   Hu, Lele ^a   Feng, Kaiyan ^c,d   Li, Yi Xue ^a   Cai, Yu Dong ^a  

^a SHANGHAI UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^d SHANGHAI CENTER FOR BIOINFORMATION TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 NAPHTHYL ISOTHIOCYANATE; 4,4' METHYLENEDIANILINE; BENZETHONIUM CHLORIDE; CARBAMAZEPINE; CHLOROXYLENOL; CISPLATIN; CITRIC ACID; COLECALCIFEROL; CRYSTAL VIOLET; CYTOCHROME P450; ERYTHROMYCIN; FLUCONAZOLE; FLUOXETINE; GERANIOL; IBUFENAC; IBUPROFEN; ITRACONAZOLE; KETOROLAC; LANSOPRAZOLE; LOMEFLOXACIN; NAPROXEN; NIMESULIDE; NYSTATIN; OXICONAZOLE; PRALIDOXIME CHLORIDE; PRAMOCAINE; PRAZIQUANTEL; ROFLUMILAST; SULINDAC; UNINDEXED DRUG; DRUG; XENOBIOTIC AGENT;

ACCURACY; ALBUMIN BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; CREATININE BLOOD LEVEL; DATA BASE; DRUG RESEARCH; EOSINOPHILIA; GENE EXPRESSION PROFILING; GLUCOSE BLOOD LEVEL; HEPATOMEGALY; INFORMATION PROCESSING; LEUKOCYTE COUNT; LIVER FIBROSIS; LIVER HYPERTROPHY; LYMPHOCYTE COUNT; MACHINE LEARNING; MEAN CORPUSCULAR HEMOGLOBIN; NONHUMAN; PREDICTION; PROTEIN BLOOD LEVEL; RAT; TOXICITY TESTING; TRIACYLGLYCEROL LIPASE BLOOD LEVEL; VALIDITY; XENOBIOTIC METABOLISM; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECT; GENE EXPRESSION REGULATION; METABOLISM; TIME;

RATTUS;

ANIMALS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MODELS, GENETIC; PHARMACEUTICAL PREPARATIONS; RATS; TIME FACTORS; XENOBIOTICS;

EID: 77949493376     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008126     Document Type: Article

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