Secreted production of Renilla luciferase in Bacillus subtilis

Biotechnology Progress

Volumn 26, Issue 2, 2010, Pages 589-594

  Chiang, Chung Jen ^a   Chen, Po Ting ^b   Chao, Yun Peng ^c  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c FENG CHIA UNIVERSITY   (Taiwan)

Author keywords

Bacillus subtilis; Renilla luciferase; Secreted protein production

Indexed keywords

BACILLUS SUBTILIS; HETEROLOGOUS PROTEINS; MAMMALIAN CELLS; MUTANT GENES; PROPEPTIDES; RENILLA LUCIFERASE; SECRETED PROTEIN; SECRETION EFFICIENCY; SIGNAL PEPTIDE; SUBTILIS; TANDEM PROMOTERS;

BACTERIOLOGY; MAMMALS; PEPTIDES; TRANSCRIPTION;

ORGANIC POLYMERS;

RECOMBINANT PROTEIN; RENILLA LUCIFERIN 2 MONOOXYGENASE; SIGNAL PEPTIDE;

ARTICLE; BACILLUS SUBTILIS; BIOSYNTHESIS; ENZYMOLOGY; GENETICS; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; SECRETION;

BACILLUS SUBTILIS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; LUCIFERASES, RENILLA; PLASMIDS; PROTEIN SORTING SIGNALS; RECOMBINANT PROTEINS;

ALCYONACEA; ANTHOZOA; BACILLUS SUBTILIS; MAMMALIA; RENILLA; RENILLA LUCIFERASE; RENILLA RENIFORMIS;

EID: 77949486278     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.351     Document Type: Article

References (30)

1. Westers L, Westers H, Quax WJ. Bacillus subtilis as cell factory for pharmaceutical proteins: a biotechnological approach to optimize the host organism. Biochimica et Biophysica Acta (BBA) - Mol Cell Res. 2004;1694:299-310.
2. Keggins KM, Lovett PS, Duvall EJ. Molecular cloning of genetically active fragments of Bacillus DNA in Bacillus subtilis and properties of the vector plasmid pUB110. Proc Natl Acad Sci USA. 1978;75:1423-1427.
3. Serrano-Heras G, Salas M, Bravo A. A new plasmid vector for regulated gene expression in Bacillus subtilis. Plasmid. 2005;54: 278-282.
4. Wu S-C, Wong S-L. Development of improved pUB110-based vectors for expression and secretion studies in Bacillus subtilis. J Biotechnol. 1999;72:185-195.
5. Bron S, Luxen E, Swart P. Instability of recombinant pUB110 plasmids in Bacillus subtilis: plasmid-encoded stability function and effects of DNA inserts. Plasmid. 1988;19:231-241.
6. Janniere L, Bruand C, Ehrlich SD. Structurally stable Bacillus subtilis cloning vectors. Gene. 1990;87:53-61.
7. Bron S, Meijer W, Holsappel S, Haima P. Plasmid instability and molecular cloning in Bacillus subtilis. Res Microbiol. 1991; 142:875-883.
8. Bron S. Plasmids. In: Harwood CR, Cutting SM, editors. Molecular Biological Methods for Bacillus. Chichester, England: Wiley; 1990:75-174.
9. Leonhardt H, Alonso JC. Parameters affecting plasmid stability in Bacillus subtilis. Gene. 1991;103:107-111.
10. Gruss A, Ehrlich SD. The family of highly interrelated singlestranded deoxyribonucleic acid plasmids. Microbiol Rev. 1989; 53:231-241.
11. Chen PT, Chiang CJ, Chao YP. Strategy to approach stable production of recombinant nattokinase in Bacillus subtilis. Biotechnol Prog. 2007;23:808-813.
12. Loren WW, McCann RO, Longiaru M, Cormierm MJ. Isolation and expression of a cDNA encoding Renilla renifomis luciferase. Proc Natl Acad Sci USA. 1991;88:4438-4442.
13. Greer LF III, Szalay AA. Imaging of light emission from the expression of luciferases in living cells and organisms: a review. Lumin. 2002;17:43-74.
14. Bryan B. Bioluminescent novelty items. US Patent 6,113,886, 2000.
15. Escher AP, Liu J. Secreted Renilla luciferase, US Patent 6, 451, 549, 2002
16. Haldimann A, Wanner BL. Conditional-replication, integration, excision, and retrieval plasmid-host systems for gene structure-function studies of bacteria. J Bacteriol. 2001;183:6384-6393.
17. Ruiqiong Y, Kim J-H, Kim B-G, Szarka S, Sihota E, Wong S-L. High-level secretory production of intact, biologically active staphylokinase from Bacillus subtilis. Biotechnol Bioeng. 1999;62:87-96.
18. Subramanian C, Woo J, Cai X, Xu X, Servick S, Nebenfuhr A, Von Arnim A. A suite of tools and application notes for in vivo protein interaction assays using bioluminescence resonance energy transfer (BRET). Plant J. 2006;48:138-152.
19. Chao YP, Chern J-T, Wen C-S, Fu H. Construction and characterization of thermo-inducible vectors derived from heat-sensitive lacI genes in combination with the T7 A1 promoter. Biotechnol Bioeng. 2002;79:1-8.
20. Chiang CJ, Chern JT, Wang JY, Chao YP. Facile immobilization of evolved Agrobacterium radiobacter carbamoylase with high thermal and oxidative stability. J Agri Food Chem. 2008; 56:6348-6354.
21. Chen PT, Chao YP. Enhancement production of recombinant nattokinase in Bacillus subtilis by the elimination of limiting factors. Biotechnol Lett. 2006;28:1595-1600.
22. Maloy SR. Experimental Techniques in Bacterial Genetics. Boston, USA: Jones and Bartlett Publishers; 1990.
23. Chen PT, Chiang CJ, Chao YP. Medium optimization for the production of recombinant nattokinase by Bacillus subtilis using response surface methodology. Biotechnol Prog. 2007;23:1327-1332.
24. Li W, Zhou X, Lu P. Bottlenecks in the expression and secretion of heterologous proteins in Bacillus subtilis. Res Microbiol. 2004;155:605-610.
25. Liu J, Escher A. Improved assay sensitivity of an engineered secreted Renilla luciferase. Gene. 1999;237:153-159.
26. Tjalsma H, Antelmann H, Jongbloed JDH, Braun PG, Darmon E, Dorenbos R, Dubois J-YF, Westers H, Zanen G, Quax WJ, Kuipers OP, Bron S, Hecker M, Van Dijl JM. Proteomics of protein secretion by Bacillus subtilis: separating the "secrets" of the secretome. Microbiol Mol Biol Rev. 2004;68:207-233.
27. Hambraeus G, Karhumaa K, Rutberg B. A 50 stem-loop and ribosome binding but not translation are important for the stability of Bacillus subtilis aprE leader mRNA. Microbiology. 2002;148:1795-1803.
28. Resnekov O, Rutberg L, Von Gabain A. Changes in the stability of specific mRNA species in response to growth stage in Bacillus subtilis. Proc Natl Acad Sci USA. 1990;87:8355-8359.
29. Pereira Y, Chambet R, Leloup L, Daguer JP, Petit-Glatron MF. Transcripts of the genes sac B, amy E, sac C, and csn expressed in Bacillus subtilis under the control of the 50 untranslated sacR region display different stabilities that can be modulated. Microbiology. 2001;147:1331-1341.
30. Daguer JP, Chambert R, Petit-Glatron MF. Increasing the stability of sacB transcript improves levansucrase production in Bacillus subtilis. Lett Appl Microbiol. 2005;41:221-226.