Efficacy of idebenone for respiratory failure in a patient with Leigh syndrome: A long-term follow-up study

Journal of the Neurological Sciences

Volumn 278, Issue 1-2, 2009, Pages 112-114

  Haginoya, Kazuhiro ^a,b   Miyabayashi, Shigeaki ^c   Kikuchi, Masahiro ^d   Kojima, Akira ^e   Yamamoto, Katsuya ^f   Omura, Kiyoshi ^g   Uematsu, Mitsugu ^b   Hino Fukuyo, Naomi ^b   Tanaka, Soichiro ^a   Tsuchiya, Shigeru ^b  

^a Takuto Rehabilitation Center for Children   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Miyabayashi Kodomo Clinic   (Japan)

^d Hitachi   (Japan)

^e Kojima Pediatric Clinic   (Japan)

^f Nankodai Yamamoto Children's Clinic   (Japan)

^g National Hospital Organization Sendai Nishitaga Hospital   (Japan)

Author keywords

Idebenone; Leigh syndrome; Mitochondrial encephalopathy; Respiratory failure

Indexed keywords

CYTOCHROME C OXIDASE; IDEBENONE; LACTIC ACID; PYRUVIC ACID; UBIDECARENONE;

ABSENCE OF SIDE EFFECTS; ADOLESCENT; ARTERIAL OXYGEN SATURATION; ARTICLE; ARTIFICIAL VENTILATION; ATAXIA; AUTOPSY; BLOOD GAS ANALYSIS; BRAIN FUNCTION; BRAIN STEM; CASE REPORT; CEREBROSPINAL FLUID; DRUG ACTIVITY; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG MECHANISM; ENZYME BLOOD LEVEL; FAMILY HISTORY; FEVER; FOLLOW UP; HOSPITAL READMISSION; HUMAN; LABORATORY TEST; LACTATE BLOOD LEVEL; LEIGH DISEASE; LONG TERM CARE; MALE; MUSCLE BIOPSY; MUTATION; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; NYSTAGMUS; POLYSOMNOGRAPHY; PRIORITY JOURNAL; REM SLEEP; RESPIRATORY FAILURE; RESPIRATORY FUNCTION; SYMPTOMATOLOGY; TIDAL VOLUME;

ADOLESCENT; BRAIN STEM; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FOLLOW-UP STUDIES; HUMANS; LACTIC ACID; LEIGH DISEASE; MALE; POLYSOMNOGRAPHY; RESPIRATION; RESPIRATORY INSUFFICIENCY; UBIQUINONE;

EID: 58749085705     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2008.11.008     Document Type: Article

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