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Volumn 29, Issue 8, 2006, Pages 703-712

Effect of ezetimibe and/or simvastatin on coenzyme Q10 levels in plasma: A randomised trial

Author keywords

[No Author keywords available]

Indexed keywords

EZETIMIBE; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SIMVASTATIN; STEROL; UBIDECARENONE;

EID: 33746848052     PISSN: 01145916     EISSN: 01145916     Source Type: Journal    
DOI: 10.2165/00002018-200629080-00007     Document Type: Article
Times cited : (86)

References (31)
  • 1
    • 0348049913 scopus 로고    scopus 로고
    • The biomolecule ubiquinone exerts a variety of biological functions
    • Nohl H, Staniek K, Kozlov AV, et al. The biomolecule ubiquinone exerts a variety of biological functions. Biofactors 2003; 18 (1-4): 23-31
    • (2003) Biofactors , vol.18 , Issue.1-4 , pp. 23-31
    • Nohl, H.1    Staniek, K.2    Kozlov, A.V.3
  • 2
    • 0025242794 scopus 로고
    • Lovastatin decreases coenzyme Q levels in humans
    • U S A
    • Folkers K, Langsjoen P, Willis R, et al. Lovastatin decreases coenzyme Q levels in humans. Proc Natl Acad Sci U S A 1990; 87 (22): 8931-4
    • (1990) Proc Natl Acad Sci , vol.87 , Issue.22 , pp. 8931-8934
    • Folkers, K.1    Langsjoen, P.2    Willis, R.3
  • 3
    • 0028226079 scopus 로고
    • Serum ubiquinone concentrations after short- and long-term treatment with HMG-CoA reductase inhibitors
    • Laaksonen R, Ojala JP, Tikkanen MJ, et al. Serum ubiquinone concentrations after short- and long-term treatment with HMG-CoA reductase inhibitors. Eur J Clin Pharmacol 1994; 46 (4): 313-7
    • (1994) Eur J Clin Pharmacol , vol.46 , Issue.4 , pp. 313-317
    • Laaksonen, R.1    Ojala, J.P.2    Tikkanen, M.J.3
  • 4
    • 0028831354 scopus 로고
    • Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-term simvastatin treatment in humans
    • Laaksonen R, Jokelainen K, Sahi T, et al. Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-term simvastatin treatment in humans. Clin Pharmacol Ther 1995; 57 (1): 62-6
    • (1995) Clin Pharmacol Ther , vol.57 , Issue.1 , pp. 62-66
    • Laaksonen, R.1    Jokelainen, K.2    Sahi, T.3
  • 5
    • 0030770430 scopus 로고    scopus 로고
    • Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors
    • Mortensen SA, Leth A, Agner E, et al. Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors. Mol Aspects Med 1997; 18 Suppl.: S137-44
    • (1997) Mol Aspects Med , vol.18 , Issue.SUPPL.
    • Mortensen, S.A.1    Leth, A.2    Agner, E.3
  • 6
    • 23644449084 scopus 로고    scopus 로고
    • The effect of HMG-CoA reductase inhibitors on coenzyme Q10: Possible biochemical/clinical implications
    • Hargreaves IP, Duncan AJ, Heales SJ, et al. The effect of HMG-CoA reductase inhibitors on coenzyme Q10: possible biochemical/clinical implications. Drug Saf 2005; 28 (8): 659-76
    • (2005) Drug Saf , vol.28 , Issue.8 , pp. 659-676
    • Hargreaves, I.P.1    Duncan, A.J.2    Heales, S.J.3
  • 7
    • 0036424159 scopus 로고    scopus 로고
    • Cholesterol absorption inhibitors for the treatment of hypercholesterolaemia
    • Sudhop T, von Bergmann K. Cholesterol absorption inhibitors for the treatment of hypercholesterolaemia. Drugs 2002; 62 (16): 2333-47
    • (2002) Drugs , vol.62 , Issue.16 , pp. 2333-2347
    • Sudhop, T.1    Von Bergmann, K.2
  • 8
    • 0037044454 scopus 로고    scopus 로고
    • Inhibition of intestinal cholesterol absorption by ezetimibe in humans
    • Sudhop T, Lutjohann D, Kodal A, et al. Inhibition of intestinal cholesterol absorption by ezetimibe in humans. Circulation 2002; 106 (15): 1943-8
    • (2002) Circulation , vol.106 , Issue.15 , pp. 1943-1948
    • Sudhop, T.1    Lutjohann, D.2    Kodal, A.3
  • 9
    • 32844468448 scopus 로고    scopus 로고
    • Monotherapy with ezetimibe causing myopathy
    • Havranek JM, Wolfsen AR, Warnke GA, et al. Monotherapy with ezetimibe causing myopathy. Am J Med 2006; 119 (3): 285-6
    • (2006) Am J Med , vol.119 , Issue.3 , pp. 285-286
    • Havranek, J.M.1    Wolfsen, A.R.2    Warnke, G.A.3
  • 10
    • 33645237749 scopus 로고    scopus 로고
    • Ezetimibe-associated myopathy in monotherapy and in combination with a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor
    • Simard C, Poirier P. Ezetimibe-associated myopathy in monotherapy and in combination with a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. Can J Cardiol 2006; 22 (2): 141-4
    • (2006) Can J Cardiol , vol.22 , Issue.2 , pp. 141-144
    • Simard, C.1    Poirier, P.2
  • 11
    • 2942604852 scopus 로고    scopus 로고
    • Ezetimibe and statin-associated myopathy
    • Fux R, Morike K, Gundel UF, et al. Ezetimibe and statin-associated myopathy. Ann Intern Med 2004; 140 (8): 671-2
    • (2004) Ann Intern Med , vol.140 , Issue.8 , pp. 671-672
    • Fux, R.1    Morike, K.2    Gundel, U.F.3
  • 12
    • 0025156823 scopus 로고
    • Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population
    • Miettinen TA, Tilvis RS, Kesaniemi Y. Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population. Am J Epidemiol 1990; 131 (1): 20-31
    • (1990) Am J Epidemiol , vol.131 , Issue.1 , pp. 20-31
    • Miettinen, T.A.1    Tilvis, R.S.2    Kesaniemi, Y.3
  • 13
    • 0036739547 scopus 로고    scopus 로고
    • Inheritance of cholesterol metabolism of probands with high or low cholesterol absorption
    • Gylling H, Miettinen TA. Inheritance of cholesterol metabolism of probands with high or low cholesterol absorption. J Lipid Res 2002; 43 (9): 1472-6
    • (2002) J Lipid Res , vol.43 , Issue.9 , pp. 1472-1476
    • Gylling, H.1    Miettinen, T.A.2
  • 14
    • 0346788998 scopus 로고    scopus 로고
    • Primary coenzyme Q10 deficiency and the brain
    • Naini A, Lewis VJ, Hirano M, et al. Primary coenzyme Q10 deficiency and the brain. Biofactors 2003; 18 (1-4): 145-52
    • (2003) Biofactors , vol.18 , Issue.1-4 , pp. 145-152
    • Naini, A.1    Lewis, V.J.2    Hirano, M.3
  • 15
    • 2942587374 scopus 로고    scopus 로고
    • Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke
    • Rundek T, Naini A, Sacco R, et al. Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke. Arch Neurol 2004; 61 (6): 889-92
    • (2004) Arch Neurol , vol.61 , Issue.6 , pp. 889-892
    • Rundek, T.1    Naini, A.2    Sacco, R.3
  • 16
    • 1542377656 scopus 로고    scopus 로고
    • Strategies for the prevention and treatment of statin-induced myopathy: Is there a role for ubiquinone supplementation?
    • Koumis T, Nathan JP, Rosenberg JM, et al. Strategies for the prevention and treatment of statin-induced myopathy: is there a role for ubiquinone supplementation? Am J Health Syst Pharm 2004; 61 (5): 515-9
    • (2004) Am J Health Syst Pharm , vol.61 , Issue.5 , pp. 515-519
    • Koumis, T.1    Nathan, J.P.2    Rosenberg, J.M.3
  • 18
    • 0037132598 scopus 로고    scopus 로고
    • Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia
    • Davidson MH, McGarry T, Bettis R, et al. Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia. J Am Coll Cardiol 2002; 40 (12): 2125-34
    • (2002) J Am Coll Cardiol , vol.40 , Issue.12 , pp. 2125-2134
    • Davidson, M.H.1    McGarry, T.2    Bettis, R.3
  • 19
    • 0030838365 scopus 로고    scopus 로고
    • The effect of simvastatin on the plasma antioxidant concentrations in patients with hypercholesterolaemia
    • Human JA, Ubbink JB, Jerling JJ, et al. The effect of simvastatin on the plasma antioxidant concentrations in patients with hypercholesterolaemia. Clin Chim Acta 1997; 263 (1): 67-77
    • (1997) Clin Chim Acta , vol.263 , Issue.1 , pp. 67-77
    • Human, J.A.1    Ubbink, J.B.2    Jerling, J.J.3
  • 20
    • 0027379891 scopus 로고
    • Plasma coenzyme Q (ubiquinone) concentrations in patients treated with simvastatin
    • Watts GF, Castelluccio C, Rice-Evans C, et al. Plasma coenzyme Q (ubiquinone) concentrations in patients treated with simvastatin. J Clin Pathol 1993; 46 (11): 1055-7
    • (1993) J Clin Pathol , vol.46 , Issue.11 , pp. 1055-1057
    • Watts, G.F.1    Castelluccio, C.2    Rice-Evans, C.3
  • 21
    • 0035859689 scopus 로고    scopus 로고
    • Coenzyme Q10 reverses pathological phenotype and reduces apoptosis in familial CoQ10 deficiency
    • Di Giovanni S, Mirabella M, Spinazzola A, et al. Coenzyme Q10 reverses pathological phenotype and reduces apoptosis in familial CoQ10 deficiency. Neurology 2001; 57 (3): 515-8
    • (2001) Neurology , vol.57 , Issue.3 , pp. 515-518
    • Di Giovanni, S.1    Mirabella, M.2    Spinazzola, A.3
  • 22
    • 0029837064 scopus 로고    scopus 로고
    • Lipid-lowering drugs and mitochondrial function: Effects of HMG-CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratio
    • DePinieux G, Chariot P, Ammi-Said M, et al. Lipid-lowering drugs and mitochondrial function: effects of HMG-CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratio. Br J Clin Pharmacol 1996; 42 (3): 333-7
    • (1996) Br J Clin Pharmacol , vol.42 , Issue.3 , pp. 333-337
    • DePinieux, G.1    Chariot, P.2    Ammi-Said, M.3
  • 23
    • 0019394333 scopus 로고
    • Effect of an inhibitor of 3-hydroxy-3-methyglutaryl coenzyme A reductase on serum lipoproteins and ubiquinone-10-levels in patients with familial hypercholesterolemia
    • Mabuchi H, Haba T, Tatami R, et al. Effect of an inhibitor of 3-hydroxy-3-methyglutaryl coenzyme A reductase on serum lipoproteins and ubiquinone-10-levels in patients with familial hypercholesterolemia. N Engl J Med 1981; 305 (9): 478-82
    • (1981) N Engl J Med , vol.305 , Issue.9 , pp. 478-482
    • Mabuchi, H.1    Haba, T.2    Tatami, R.3
  • 24
    • 7944221535 scopus 로고    scopus 로고
    • Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction
    • Silver MA, Langsjoen PH, Szabo S, et al. Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction. Am J Cardiol 2005; 94: 1306-10
    • (2005) Am J Cardiol , vol.94 , pp. 1306-1310
    • Silver, M.A.1    Langsjoen, P.H.2    Szabo, S.3
  • 25
    • 0025257393 scopus 로고
    • The effects of inducers of the endoplasmic reticulum peroxisomes and mitochondria on the amounts and synthesis of ubiquinone in rat liver subcellular membranes
    • Kalen A, Appelkvist EL, Dallner G. The effects of inducers of the endoplasmic reticulum peroxisomes and mitochondria on the amounts and synthesis of ubiquinone in rat liver subcellular membranes. Chem Biol Interact 1990; 73: 221-34
    • (1990) Chem Biol Interact , vol.73 , pp. 221-234
    • Kalen, A.1    Appelkvist, E.L.2    Dallner, G.3
  • 26
    • 0019135838 scopus 로고
    • Multivalent feedback regulation of HMG-CoA reductase: A control mechanism coordinating isoprenoid synthesis and cell growth
    • Brown MS, Goldstein JL. Multivalent feedback regulation of HMG-CoA reductase: a control mechanism coordinating isoprenoid synthesis and cell growth. J Lipid Res 1980; 21: 505-17
    • (1980) J Lipid Res , vol.21 , pp. 505-517
    • Brown, M.S.1    Goldstein, J.L.2
  • 27
    • 0025728462 scopus 로고
    • Effects of pravastatin and cholestyramine on products of the mevalonate pathway in familial hypercholesterolemia
    • Elmberger PG, Kalen A, Lund E, et al. Effects of pravastatin and cholestyramine on products of the mevalonate pathway in familial hypercholesterolemia. J Lipid Res 1991; 32 (6): 935-40
    • (1991) J Lipid Res , vol.32 , Issue.6 , pp. 935-940
    • Elmberger, P.G.1    Kalen, A.2    Lund, E.3
  • 28
    • 0031982317 scopus 로고    scopus 로고
    • Gemfibrozil-induced decrease in serum ubiquinone and alpha- and gammatocopherol levels in men with combined hyperlipidaemia
    • Aberg F, Appelkvist EL, Broijersen A, et al. Gemfibrozil-induced decrease in serum ubiquinone and alpha- and gammatocopherol levels in men with combined hyperlipidaemia. Eur J Clin Invest 1998; 28 (3): 235-42
    • (1998) Eur J Clin Invest , vol.28 , Issue.3 , pp. 235-242
    • Aberg, F.1    Appelkvist, E.L.2    Broijersen, A.3
  • 29
    • 0033060987 scopus 로고    scopus 로고
    • Effects of lipid-lowering drugs on left ventricular function and exercise tolerance in dyslipidemic coronary patients
    • De Lorgeril M, Salen P, Bontemps L, et al. Effects of lipid-lowering drugs on left ventricular function and exercise tolerance in dyslipidemic coronary patients. J Cardiovasc Pharmacol 1999; 33: 473-8
    • (1999) J Cardiovasc Pharmacol , vol.33 , pp. 473-478
    • De Lorgeril, M.1    Salen, P.2    Bontemps, L.3
  • 30
    • 0028352008 scopus 로고
    • Effects of clofibrate, phthalates and probucol on ubiquinone levels
    • Aberg F, Zhang Y, Appelkvist EL, et al. Effects of clofibrate, phthalates and probucol on ubiquinone levels. Chem Biol Interact 1994; 91: 1-14
    • (1994) Chem Biol Interact , vol.91 , pp. 1-14
    • Aberg, F.1    Zhang, Y.2    Appelkvist, E.L.3
  • 31
    • 0029278917 scopus 로고
    • Serum and muscle tissue ubiquinone levels in healthy subjects
    • Laaksonen R, Riihimaki A, Laitila J, et al. Serum and muscle tissue ubiquinone levels in healthy subjects. J Lab Clin Med 1995; 125: 517-21
    • (1995) J Lab Clin Med , vol.125 , pp. 517-521
    • Laaksonen, R.1    Riihimaki, A.2    Laitila, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.