Molecular cloning of a ferret angiotensin II AT1 receptor reveals the importance of position 163 for Losartan binding

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1497, Issue 1, 2000, Pages 94-102

  Gosselin, Mylène J ^a   Leclerc, Patrice C ^a   Auger Messier, Mannix ^a   Guillemette, Gaétan ^a   Escher, Emanuel ^a   Leduc, Richard ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

Angiotensin II type 1 receptor; Angiotensin II type 1 receptor antagonist; Gene cloning; Losartan; Mustela putorius furo; Receptor binding

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 2 ETHYL 5,7 DIMETHYL 3 [4 [2 (2H TETRAZOL 5 YL)PHENYL]BENZYL]IMIDAZO[4,5 B]PYRIDINE; ANGIOTENSIN 2 RECEPTOR; COMPLEMENTARY DNA; LOSARTAN POTASSIUM;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DNA LIBRARY; FERRET; HEART ATRIUM; HEART FAILURE; HYPERTENSION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

1-SARCOSINE-8-ISOLEUCINE ANGIOTENSIN II; ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANGIOTENSIN II; ANIMALS; BASE SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; CLONING, MOLECULAR; COS CELLS; DNA, COMPLEMENTARY; DNA, RECOMBINANT; FERRETS; IMIDAZOLES; IODINE RADIOISOTOPES; LOSARTAN; MOLECULAR SEQUENCE DATA; PLASMIDS; PROTEIN BINDING; PYRIDINES; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; THREONINE;

EID: 0034595571     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4889(00)00046-X     Document Type: Article

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