-
1
-
-
34547842304
-
Pathogenesis and mechanism of disease progression from hemophagocytic lymphohistiocytosis to Epstein-Barr virus-associated T-cell lymphoma: Nuclear factor-kappa B pathway as a potential therapeutic target
-
Chuang HC, Lay JD, Hsieh WC, Su IJ. Pathogenesis and mechanism of disease progression from hemophagocytic lymphohistiocytosis to Epstein-Barr virus-associated T-cell lymphoma: nuclear factor-kappa B pathway as a potential therapeutic target. Cancer Sci 2007; 98:1281-1287.
-
(2007)
Cancer Sci
, vol.98
, pp. 1281-1287
-
-
Chuang, H.C.1
Lay, J.D.2
Hsieh, W.C.3
Su, I.J.4
-
2
-
-
13844255756
-
Review of hemophagocytic lymphohistiocytosis (HLH) in children with focus on Japanese experiences
-
Ishii E, Ohga S, Imashuku S, et al. Review of hemophagocytic lymphohistiocytosis (HLH) in children with focus on Japanese experiences. Crit Rev Oncol Hematol 2005; 53:209-223.
-
(2005)
Crit Rev Oncol Hematol
, vol.53
, pp. 209-223
-
-
Ishii, E.1
Ohga, S.2
Imashuku, S.3
-
3
-
-
0037038866
-
Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: A mechanism for the unusual severity of human disease?
-
Cheung CY, Poon LL, Lau AS, et al. Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease? Lancet 2002; 360:1831-1837.
-
(2002)
Lancet
, vol.360
, pp. 1831-1837
-
-
Cheung, C.Y.1
Poon, L.L.2
Lau, A.S.3
-
4
-
-
0035140519
-
Pathology of fatal human infection associated with avian influenza A H5N1 virus
-
To KF, Chan PK, Chan KF, et al. Pathology of fatal human infection associated with avian influenza A H5N1 virus. J Med Virol 2001; 63:242-246.
-
(2001)
J Med Virol
, vol.63
, pp. 242-246
-
-
To, K.F.1
Chan, P.K.2
Chan, K.F.3
-
5
-
-
1442274795
-
Pathogenesis of hemophagocytic syndrome (HPS)
-
Larroche C, Mouthon L. Pathogenesis of hemophagocytic syndrome (HPS). Autoimmun Rev 2004; 3:69-75.
-
(2004)
Autoimmun Rev
, vol.3
, pp. 69-75
-
-
Larroche, C.1
Mouthon, L.2
-
6
-
-
43449101851
-
Perspectives on the pathogenesis and therapy of hemophagocytic syndrome
-
Su IJ. Perspectives on the pathogenesis and therapy of hemophagocytic syndrome. J Formos Med Assoc 2008; 107:277-280.
-
(2008)
J Formos Med Assoc
, vol.107
, pp. 277-280
-
-
Su, I.J.1
-
7
-
-
0037261728
-
Epstein-barr virus latent membrane protein-1 mediates upregulation of tumor necrosis factor-alpha in EBV-infected T cells: Implications for the pathogenesis of hemophagocytic syndrome
-
Lay JD, Chuang SE, Rowe M, Su IJ. Epstein-barr virus latent membrane protein-1 mediates upregulation of tumor necrosis factor-alpha in EBV-infected T cells: implications for the pathogenesis of hemophagocytic syndrome. J Biomed Sci 2003; 10:146-155.
-
(2003)
J Biomed Sci
, vol.10
, pp. 146-155
-
-
Lay, J.D.1
Chuang, S.E.2
Rowe, M.3
Su, I.J.4
-
8
-
-
0030770948
-
Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virusinfected T cells in the pathogenesis of hemophagocytic syndrome
-
Lay JD, Tsao CJ, Chen JY, Kadin ME, Su IJ. Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virusinfected T cells in the pathogenesis of hemophagocytic syndrome. J Clin Invest 1997; 100:1969-1979.
-
(1997)
J Clin Invest
, vol.100
, pp. 1969-1979
-
-
Lay, J.D.1
Tsao, C.J.2
Chen, J.Y.3
Kadin, M.E.4
Su, I.J.5
-
9
-
-
27644592071
-
Epstein-Barr virus LMP1 inhibits the expression of SAP gene and upregulates Th1 cytokines in the pathogenesis of hemophagocytic syndrome
-
Chuang HC, Lay JD, Hsieh WC, et al. Epstein-Barr virus LMP1 inhibits the expression of SAP gene and upregulates Th1 cytokines in the pathogenesis of hemophagocytic syndrome. Blood 2005; 106:3090- 3096.
-
(2005)
Blood
, vol.106
, pp. 3090-3096
-
-
Chuang, H.C.1
Lay, J.D.2
Hsieh, W.C.3
-
10
-
-
0036013414
-
Biology and treatment of familial hemophagocytic lymphohistiocytosis: Importance of perforin in lymphocyte-mediated cytotoxicity and triggering of apoptosis
-
Henter JI. Biology and treatment of familial hemophagocytic lymphohistiocytosis: importance of perforin in lymphocyte-mediated cytotoxicity and triggering of apoptosis. Med Pediatr Oncol 2002; 38:305-309.
-
(2002)
Med Pediatr Oncol
, vol.38
, pp. 305-309
-
-
Henter, J.I.1
-
11
-
-
0034923501
-
Peroxisome proliferator-activated receptor gamma and metabolic disease
-
Willson TM, Lambert MH, Kliewer SA. Peroxisome proliferator-activated receptor gamma and metabolic disease. Annu Rev Biochem 2001; 70:341-367
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 341-367
-
-
Willson, T.M.1
Lambert, M.H.2
Kliewer, S.A.3
-
12
-
-
33751545838
-
A placebocontrolled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
-
Belfort R, Harrison SA, Brown K, et al. A placebocontrolled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med 2006; 355:2297-2307.
-
(2006)
N Engl J Med
, vol.355
, pp. 2297-2307
-
-
Belfort, R.1
Harrison, S.A.2
Brown, K.3
-
13
-
-
0031886864
-
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
-
Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998; 391:79-82.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
14
-
-
0031888958
-
PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
-
Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998; 391:82-86.
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
15
-
-
0001297403
-
Activation of human T lymphocytes is inhibited by peroxisome proliferatoractivated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT
-
Yang XY, Wang LH, Chen T, et al. Activation of human T lymphocytes is inhibited by peroxisome proliferatoractivated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT. J Biol Chem 2000; 275:4541-4544.
-
(2000)
J Biol Chem
, vol.275
, pp. 4541-4544
-
-
Yang, X.Y.1
Wang, L.H.2
Chen, T.3
-
16
-
-
28444455582
-
PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways
-
Appel S, Mirakaj V, Bringmann A, Weck MM, Grunebach F, Brossart P. PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways. Blood 2005; 106:3888-3894.
-
(2005)
Blood
, vol.106
, pp. 3888-3894
-
-
Appel, S.1
Mirakaj, V.2
Bringmann, A.3
Weck, M.M.4
Grunebach, F.5
Brossart, P.6
-
17
-
-
0036738829
-
Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects
-
Skolnik PR, Rabbi MF, Mathys JM, Greenberg AS. Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects. J Acquir Immune Defic Syndr 2002; 31:1-10.
-
(2002)
J Acquir Immune Defic Syndr
, vol.31
, pp. 1-10
-
-
Skolnik, P.R.1
Rabbi, M.F.2
Mathys, J.M.3
Greenberg, A.S.4
-
18
-
-
33644825094
-
Peroxisome-proliferator-activated receptor-gamma agonists inhibit the release of proinflammatory cytokines from RSV-infected epithelial cells
-
Arnold R, Konig W. Peroxisome-proliferator-activated receptor-gamma agonists inhibit the release of proinflammatory cytokines from RSV-infected epithelial cells. Virology 2006; 346:427-439.
-
(2006)
Virology
, vol.346
, pp. 427-439
-
-
Arnold, R.1
Konig, W.2
-
19
-
-
0035069985
-
An animal model for human EBV-associated hemophagocytic syndrome: Herpesvirus papio frequently induces fatal lymphoproliferative disorders with hemophagocytic syndrome in rabbits
-
Hayashi K, Ohara N, Teramoto N, et al. An animal model for human EBV-associated hemophagocytic syndrome: herpesvirus papio frequently induces fatal lymphoproliferative disorders with hemophagocytic syndrome in rabbits. Am J Pathol 2001; 158:1533-1542.
-
(2001)
Am J Pathol
, vol.158
, pp. 1533-1542
-
-
Hayashi, K.1
Ohara, N.2
Teramoto, N.3
-
20
-
-
0036792223
-
Animal in vivo models of EBV-associated lymphoproliferative diseases: Special references to rabbit models
-
Hayashi K, Teramoto N, Akagi T. Animal in vivo models of EBV-associated lymphoproliferative diseases: special references to rabbit models. Histol Histopathol 2002; 17:1293-1310.
-
(2002)
Histol Histopathol
, vol.17
, pp. 1293-1310
-
-
Hayashi, K.1
Teramoto, N.2
Akagi, T.3
-
21
-
-
0019238060
-
Comparative studies of herpesvirus papio (baboon herpesvirus) DNA and Epstein-Barr virus DNA
-
Lee YS, Tanaka A, Lau RY, Nonoyama M, Rabin H. Comparative studies of herpesvirus papio (baboon herpesvirus) DNA and Epstein-Barr virus DNA. J Gen Virol 1980; 51:245-253.
-
(1980)
J Gen Virol
, vol.51
, pp. 245-253
-
-
Lee, Y.S.1
Tanaka, A.2
Lau, R.Y.3
Nonoyama, M.4
Rabin, H.5
-
22
-
-
34250803927
-
Emergence of antired blood cell antibodies triggers red cell phagocytosis by activated macrophages in a rabbit model of Epstein-Barr virus-associated hemophagocytic syndrome
-
Hsieh WC, Chang Y, Hsu MC, et al. Emergence of antired blood cell antibodies triggers red cell phagocytosis by activated macrophages in a rabbit model of Epstein-Barr virus-associated hemophagocytic syndrome. Am J Pathol 2007; 170:1629-1639.
-
(2007)
Am J Pathol
, vol.170
, pp. 1629-1639
-
-
Hsieh, W.C.1
Chang, Y.2
Hsu, M.C.3
-
23
-
-
0141532275
-
Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone
-
Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, Oliver D, Bacon BR. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone. Hepatology 2003; 38:1008-1017.
-
(2003)
Hepatology
, vol.38
, pp. 1008-1017
-
-
Neuschwander-Tetri, B.A.1
Brunt, E.M.2
Wehmeier, K.R.3
Oliver, D.4
Bacon, B.R.5
-
24
-
-
1442355447
-
A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis
-
Promrat K, Lutchman G, Uwaifo GI, et al. A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology 2004; 39:188-196.
-
(2004)
Hepatology
, vol.39
, pp. 188-196
-
-
Promrat, K.1
Lutchman, G.2
Uwaifo, G.I.3
-
25
-
-
1942518840
-
PPARs and the complex journey to obesity
-
Evans RM, Barish GD, Wang YX. PPARs and the complex journey to obesity. Nat Med 2004; 10:355-361.
-
(2004)
Nat Med
, vol.10
, pp. 355-361
-
-
Evans, R.M.1
Barish, G.D.2
Wang, Y.X.3
-
26
-
-
33644547706
-
Nonalcoholic fatty liver disease: From steatosis to cirrhosis
-
Farrell GC, Larter CZ. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 2006; 43:S99-S112.
-
(2006)
Hepatology
, vol.43
-
-
Farrell, G.C.1
Larter, C.Z.2
-
27
-
-
0142144332
-
Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands as bifunctional regulators of cell proliferation
-
Na HK, Surh YJ. Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands as bifunctional regulators of cell proliferation. Biochem Pharmacol 2003; 66:1381-1391.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 1381-1391
-
-
Na, H.K.1
Surh, Y.J.2
-
28
-
-
0347357686
-
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptorgamma, reduces acute inflammation
-
Cuzzocrea S, Pisano B, Dugo L, et al. Rosiglitazone, a ligand of the peroxisome proliferator-activated receptorgamma, reduces acute inflammation. Eur J Pharmacol 2004; 483:79-93.
-
(2004)
Eur J Pharmacol
, vol.483
, pp. 79-93
-
-
Cuzzocrea, S.1
Pisano, B.2
Dugo, L.3
-
29
-
-
0343855442
-
Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer
-
Mueller E, Smith M, Sarraf P, et al. Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer. Proc Natl Acad Sci U S A 2000; 97:10990-10995.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10990-10995
-
-
Mueller, E.1
Smith, M.2
Sarraf, P.3
-
30
-
-
21144439861
-
Chemopreventive effect of peroxisome proliferator-activated receptor gamma on gastric carcinogenesis in mice
-
Lu J, Imamura K, Nomura S, et al. Chemopreventive effect of peroxisome proliferator-activated receptor gamma on gastric carcinogenesis in mice. Cancer Res 2005; 65:4769-4774.
-
(2005)
Cancer Res
, vol.65
, pp. 4769-4774
-
-
Lu, J.1
Imamura, K.2
Nomura, S.3
-
31
-
-
31544464135
-
Inhibition of bladder tumor growth by 1,1-bis(3′-indolyl)-1-(p- substitutedphenyl)methanes: A new class of peroxisome proliferator-activated receptor gamma agonists
-
Kassouf W, Chintharlapalli S, Abdelrahim M, Nelkin G, Safe S, Kamat AM. Inhibition of bladder tumor growth by 1,1-bis(3′-indolyl)-1-(p- substitutedphenyl)methanes: a new class of peroxisome proliferator-activated receptor gamma agonists. Cancer Res 2006; 66:412-418.
-
(2006)
Cancer Res
, vol.66
, pp. 412-418
-
-
Kassouf, W.1
Chintharlapalli, S.2
Abdelrahim, M.3
Nelkin, G.4
Safe, S.5
Kamat, A.M.6
-
32
-
-
0347334750
-
IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/ COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis
-
Jung YJ, Isaacs JS, Lee S, Trepel J, Neckers L. IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/ COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis. FASEB J 2003; 17:2115-2117.
-
(2003)
FASEB J
, vol.17
, pp. 2115-2117
-
-
Jung, Y.J.1
Isaacs, J.S.2
Lee, S.3
Trepel, J.4
Neckers, L.5
-
34
-
-
34748855636
-
NFKB and NFKBI polymorphisms in relation to susceptibility of tumour and other diseases
-
Sun XF, Zhang H. NFKB and NFKBI polymorphisms in relation to susceptibility of tumour and other diseases. Histol Histopathol 2007; 22:1387-1398.
-
(2007)
Histol Histopathol
, vol.22
, pp. 1387-1398
-
-
Sun, X.F.1
Zhang, H.2
-
35
-
-
34247150706
-
Statins and sepsis: Multiple modifications at multiple levels
-
Terblanche M, Almog Y, Rosenson RS, Smith TS, Hackam DG. Statins and sepsis: multiple modifications at multiple levels. Lancet Infect Dis 2007; 7:358-368.
-
(2007)
Lancet Infect Dis
, vol.7
, pp. 358-368
-
-
Terblanche, M.1
Almog, Y.2
Rosenson, R.S.3
Smith, T.S.4
Hackam, D.G.5
-
36
-
-
21844463540
-
Statin treatment after onset of sepsis in a murine model improves survival
-
Merx MW, Liehn EA, Graf J, et al. Statin treatment after onset of sepsis in a murine model improves survival. Circulation 2005; 112:117-124.
-
(2005)
Circulation
, vol.112
, pp. 117-124
-
-
Merx, M.W.1
Liehn, E.A.2
Graf, J.3
-
37
-
-
2642553075
-
HMG-CoA reductase inhibitor simvastatin profoundly improves survival in a murine model of sepsis
-
Merx MW, Liehn EA, Janssens U, et al. HMG-CoA reductase inhibitor simvastatin profoundly improves survival in a murine model of sepsis. Circulation 2004; 109:2560-2565.
-
(2004)
Circulation
, vol.109
, pp. 2560-2565
-
-
Merx, M.W.1
Liehn, E.A.2
Janssens, U.3
-
38
-
-
33947541266
-
Activation of JNKdependent pathway is required for HIV viral protein R-induced apoptosis in human monocytic cells: Involvement of antiapoptotic BCL2 and c-IAP1 genes
-
Mishra S, Mishra JP, Kumar A. Activation of JNKdependent pathway is required for HIV viral protein R-induced apoptosis in human monocytic cells: involvement of antiapoptotic BCL2 and c-IAP1 genes. J Biol Chem 2007; 282:4288-4300.
-
(2007)
J Biol Chem
, vol.282
, pp. 4288-4300
-
-
Mishra, S.1
Mishra, J.P.2
Kumar, A.3
-
39
-
-
43949109962
-
Acetylsalicylic acid inhibits hepatitis C virus RNA and protein expression through cyclooxygenase 2 signaling pathways
-
Trujillo-Murillo K, Rincon-Sanchez AR, Martinez-Rodriguez H, et al. Acetylsalicylic acid inhibits hepatitis C virus RNA and protein expression through cyclooxygenase 2 signaling pathways. Hepatology 2008; 47:1462-1472.
-
(2008)
Hepatology
, vol.47
, pp. 1462-1472
-
-
Trujillo-Murillo, K.1
Rincon-Sanchez, A.R.2
Martinez-Rodriguez, H.3
-
40
-
-
44849085529
-
Suppression of p38 mitogen-activated protein kinase inhibits hepatitis B virus replication in human hepatoma cell: The antiviral role of nitric oxide
-
Chang WW, Su IJ, Chang WT, Huang W, Lei HY. Suppression of p38 mitogen-activated protein kinase inhibits hepatitis B virus replication in human hepatoma cell: the antiviral role of nitric oxide. J Viral Hepat 2008; 15:490-497.
-
(2008)
J Viral Hepat
, vol.15
, pp. 490-497
-
-
Chang, W.W.1
Su, I.J.2
Chang, W.T.3
Huang, W.4
Lei, H.Y.5
-
41
-
-
33749511112
-
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia
-
de Jong MD, Simmons CP, Thanh TT, et al. Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat Med 2006; 12:1203-1207.
-
(2006)
Nat Med
, vol.12
, pp. 1203-1207
-
-
de Jong, M.D.1
Simmons, C.P.2
Thanh, T.T.3
|