Overview: Biology and treatment of familial hemophagocytic lymphohistiocytosis: Importance of perforin in lymphocyte-mediated cytotoxicity and triggering of apoptosis

Medical and Pediatric Oncology

Volumn 38, Issue 5, 2002, Pages 305-309

  Henter, Jan Inge ^a,b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Apoptosis; Cytotoxicity; Familial hemophagocytic lymphohistiocytosis; Natural killer cell; Perforin

Indexed keywords

CYTOKINE; PERFORIN; MEMBRANE PROTEIN; PORE FORMING CYTOTOXIC PROTEIN;

APOPTOSIS; CHILD; CHILDHOOD DISEASE; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; FAMILIAL DISEASE; FEVER; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HISTIOCYTOSIS; HUMAN; IMMUNOREGULATION; INFANT; LYMPHOCYTE; NATURAL KILLER CELL; PANCYTOPENIA; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RETICULOSIS; REVIEW; SPLENOMEGALY; T LYMPHOCYTE SUBPOPULATION; DIFFERENTIAL DIAGNOSIS; GENETICS; INFLAMMATION; NEWBORN; PHYSIOLOGY; PRESCHOOL CHILD;

APOPTOSIS; CHILD; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; HISTIOCYTOSIS, NON-LANGERHANS-CELL; HUMANS; INFANT; INFANT, NEWBORN; INFLAMMATION; KILLER CELLS, NATURAL; MEMBRANE GLYCOPROTEINS; PORE FORMING CYTOTOXIC PROTEINS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0036013414     PISSN: 00981532     EISSN: None     Source Type: Journal    
DOI: 10.1002/mpo.1340     Document Type: Review

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