Enhanced functionality of T cell receptor-redirected T cells is defined by the transgene cassette

Journal of Molecular Medicine

Volumn 86, Issue 5, 2008, Pages 573-583

  Leisegang, Matthias ^a   Engels, Boris ^b   Meyerhuber, Peter ^c   Kieback, Elisa ^a   Sommermeyer, Daniel ^a   Xue, Shao An ^d   Reuß, Simone ^a   Stauss, Hans ^d   Uckert, Wolfgang ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b UNIVERSITY OF CHICAGO   (United States)

^c HUMBOLDT UNIVERSITY   (Germany)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

2A peptide; IRES; Retroviral vector; T cell avidity; T cell receptor

Indexed keywords

EPITOPE; GAMMA INTERFERON; GLYCOPROTEIN GP33; PEPTIDE; RETROVIRUS VECTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TETRAMER; VIRUS GLYCOPROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARENAVIRUS; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOKINE RELEASE; GENE CASSETTE; GENE CONSTRUCT; GENE EXPRESSION; GENE FUNCTION; GENE NUMBER; GENE TRANSFER; GENE VECTOR; INTERNAL RIBOSOME ENTRY SITE; LYMPHOCYTE FUNCTION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR GENE; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; TRANSGENE; WILD TYPE;

ANIMALS; CELL LINE; CELL MEMBRANE; GENE DOSAGE; GENE EXPRESSION REGULATION; GENETIC VECTORS; HUMANS; MICE; MICE, INBRED C57BL; MUTAGENESIS, INSERTIONAL; PEPTIDES; RECEPTORS, ANTIGEN, T-CELL; RETROVIRIDAE; RNA, MESSENGER; T-LYMPHOCYTES; TRANSGENES;

EID: 43049101949     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-008-0317-3     Document Type: Article

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