Human ATP synthase beta is phosphorylated at multiple sites and shows abnormal phosphorylation at specific sites in insulin-resistant muscle

Diabetologia

Volumn 53, Issue 3, 2010, Pages 541-551

  Hojlund K ^a,b   Yi, Z ^a   Lefort, N ^a,c   Langlais, P ^a,c   Bowen, B ^d   Levin, K ^b   Beck Nielsen, H ^b   Mandarino, L J ^a,c  

^a ARIZONA STATE UNIVERSITY   (United States)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

^c ARIZONA STATE UNIVERSITY   (United States)

^d Arizona State University   (United States)

Author keywords

ATP synthase; Insulin resistance; Mass spectrometry; Mitochondrial oxidative phosphorylation; Obesity; Proteomics; Type 2 diabetes

Indexed keywords

INSULIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE BETA; UNCLASSIFIED DRUG; ATP5B PROTEIN, HUMAN; TYROSINE;

ADULT; ARTICLE; CLAMP; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC PATIENT; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; FEMALE; HUMAN; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INSULIN RESISTANCE; MALE; MUSCLE BIOPSY; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEOTIDE BINDING SITE; OBESITY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SKELETAL MUSCLE; TANDEM MASS SPECTROMETRY; BINDING SITE; CATALYSIS; CHEMISTRY; COHORT ANALYSIS; METABOLISM; MIDDLE AGED; MUSCLE; PATHOLOGY; PHOSPHORYLATION;

ADULT; BINDING SITES; CATALYSIS; COHORT STUDIES; FEMALE; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; MIDDLE AGED; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MUSCLE, SKELETAL; MUSCLES; PHOSPHORYLATION; TYROSINE;

EID: 77949272758     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1624-0     Document Type: Article

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