-
1
-
-
4544318079
-
The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma 1(PPARgamma 1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma 1 transcriptional activation: Involvement in flow-induced PPARgamma activation in endothelial cells
-
Akaike M, Che W, Marmarosh NL, Ohta S, Osawa M, Ding B, Berk BC, Yan C, Abe J. 2004. The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma 1(PPARgamma 1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma 1 transcriptional activation: Involvement in flow-induced PPARgamma activation in endothelial cells. Mol Cell Biol 24:8691-8704.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8691-8704
-
-
Akaike, M.1
Che, W.2
Marmarosh, N.L.3
Ohta, S.4
Osawa, M.5
Ding, B.6
Berk, B.C.7
Yan, C.8
Abe, J.9
-
2
-
-
0035845631
-
Hypertensive endorgan damage and premature mortality are p38 mitogen-activated protein kinase-dependent in a rat model of cardiac hypertrophy and dysfunction
-
Behr TM, Nerurkar SS, Nelson AH, Coatney RW, Woods TN, Sulpizio A, Chandra S, Brooks DP, Kumar S, Lee JC, Ohlstein EH, Angermann CE, Adams JL, Sisko J, Sackner-Bernstein JD, Willette RN. 2001. Hypertensive endorgan damage and premature mortality are p38 mitogen-activated protein kinase-dependent in a rat model of cardiac hypertrophy and dysfunction. Circulation 11:1292-1298.
-
(2001)
Circulation
, vol.11
, pp. 1292-1298
-
-
Behr, T.M.1
Nerurkar, S.S.2
Nelson, A.H.3
Coatney, R.W.4
Woods, T.N.5
Sulpizio, A.6
Chandra, S.7
Brooks, D.P.8
Kumar, S.9
Lee, J.C.10
Ohlstein, E.H.11
Angermann, C.E.12
Adams, J.L.13
Sisko, J.14
Sackner-Bernstein, J.D.15
Willette, R.N.16
-
3
-
-
0032917447
-
Increased protein kinase C activity and expression of Ca2+-sensitive isoforms in the failing human heart
-
Bowling N, Walsh RA, Song G, Estridge T, Sandusky GE, Fouts RL, Mintze K, Pickard T, Roden R, Bristow MR, Sabbah HN, Mizrahi JL, Gromo G, King GL, Vlahos CJ. 1999. Increased protein kinase C activity and expression of Ca2+-sensitive isoforms in the failing human heart. Circulation 99:384-391.
-
(1999)
Circulation
, vol.99
, pp. 384-391
-
-
Bowling, N.1
Walsh, R.A.2
Song, G.3
Estridge, T.4
Sandusky, G.E.5
Fouts, R.L.6
Mintze, K.7
Pickard, T.8
Roden, R.9
Bristow, M.R.10
Sabbah, H.N.11
Mizrahi, J.L.12
Gromo, G.13
King, G.L.14
Vlahos, C.J.15
-
4
-
-
1642388834
-
PKC-alpha regulates cardiac contractility and propensity toward heart failure
-
Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, Robbins J, Hewett TE, Bibb JA, Westfall MV, Kranias EG, Molkentin JD. 2004. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nat Med 10:248-254.
-
(2004)
Nat Med
, vol.10
, pp. 248-254
-
-
Braz, J.C.1
Gregory, K.2
Pathak, A.3
Zhao, W.4
Sahin, B.5
Klevitsky, R.6
Kimball, T.F.7
Lorenz, J.N.8
Nairn, A.C.9
Liggett, S.B.10
Bodi, I.11
Wang, S.12
Schwartz, A.13
Lakatta, E.G.14
DePaoli-Roach, A.A.15
Robbins, J.16
Hewett, T.E.17
Bibb, J.A.18
Westfall, M.V.19
Kranias, E.G.20
Molkentin, J.D.21
more..
-
5
-
-
0346848839
-
Cardiac hypertrophy is associated with decreased eNOS expression in angiotensin AT2 receptor-deficient mice
-
Brede M, Roell W, Ritter O, Wiesmann F, Jahns R, Haase A, Fleischmann BK, Hein L. 2003. Cardiac hypertrophy is associated with decreased eNOS expression in angiotensin AT2 receptor-deficient mice. Hypertension 42:1177-1182.
-
(2003)
Hypertension
, vol.42
, pp. 1177-1182
-
-
Brede, M.1
Roell, W.2
Ritter, O.3
Wiesmann, F.4
Jahns, R.5
Haase, A.6
Fleischmann, B.K.7
Hein, L.8
-
6
-
-
0035910603
-
The dual-specificity phosphatase MKP-1 limits the cardiac hypertrophic response in vitro and in vivo
-
Bueno OF, De Windt LJ, Lim HW, Tymitz KM, Witt SA, Kimball TR, Molkentin JD. 2001. The dual-specificity phosphatase MKP-1 limits the cardiac hypertrophic response in vitro and in vivo. Circ Res 88:88-96.
-
(2001)
Circ Res
, vol.88
, pp. 88-96
-
-
Bueno, O.F.1
De Windt, L.J.2
Lim, H.W.3
Tymitz, K.M.4
Witt, S.A.5
Kimball, T.R.6
Molkentin, J.D.7
-
7
-
-
13244291607
-
The unique C-terminal tail of mitogenactivated protein kinase ERK5 regulates its activation and nuclear shuttling
-
Buschbeck M, Ullrich A. 2005. The unique C-terminal tail of mitogenactivated protein kinase ERK5 regulates its activation and nuclear shuttling. J Biol Chem 280:2659-2667.
-
(2005)
J Biol Chem
, vol.280
, pp. 2659-2667
-
-
Buschbeck, M.1
Ullrich, A.2
-
8
-
-
67249116436
-
Crocetin protects against cardiac hypertrophy by blocking MEK-ERK1/2 signalling pathway
-
Cai J, Yi FF, Bian ZY, Shen DF, Yang L, Yan L, Tang QZ, Yang XC, Li H. 2009. Crocetin protects against cardiac hypertrophy by blocking MEK-ERK1/2 signalling pathway. J Cell Mol Med 13:909-925.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 909-925
-
-
Cai, J.1
Yi, F.F.2
Bian, Z.Y.3
Shen, D.F.4
Yang, L.5
Yan, L.6
Tang, Q.Z.7
Yang, X.C.8
Li, H.9
-
9
-
-
0035949580
-
Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC
-
Chen L, Hahn H, Wu G, Chen CH, Liron T, Schechtman D, Cavallaro G, Banci L, Guo Y, Bolli R, Dorn GW II, Mochly-Rosen D. 2001. Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC. Proc Natl Acad Sci USA 98(20): 11114-11119.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.20
, pp. 11114-11119
-
-
Chen, L.1
Hahn, H.2
Wu, G.3
Chen, C.H.4
Liron, T.5
Schechtman, D.6
Cavallaro, G.7
Banci, L.8
Guo, Y.9
Bolli, R.10
Dorn II, G.W.11
Mochly-Rosen, D.12
-
10
-
-
34547228831
-
Atypical mitogen-activated protein kinases: Structure, regulation and functions
-
Coulombe P, Meloche S. 2007. Atypical mitogen-activated protein kinases: Structure, regulation and functions. Biochim Biophys Acta 1773:1376-1387.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1376-1387
-
-
Coulombe, P.1
Meloche, S.2
-
11
-
-
0030610854
-
Transgenic Galphaq overexpression induces cardiac contractile failure in mice
-
D'Angelo DD, Sakata Y, Lorenz JN, Boivin GP, Walsh RA, Liggett SB, Dorn GW II. 1997. Transgenic Galphaq overexpression induces cardiac contractile failure in mice. Proc Natl Acad Sci USA 94:8121-8126.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8121-8126
-
-
D'Angelo, D.D.1
Sakata, Y.2
Lorenz, J.N.3
Boivin, G.P.4
Walsh, R.A.5
Liggett, S.B.6
Dorn II, G.W.7
-
12
-
-
0033830338
-
Protein kinase C isozymes and the regulation of diverse cell responses
-
Dempsey EC, Newton AC, Mochly-Rosen D, Fields AP, Reyland ME, Insel PA, Messing RO. 2000. Protein kinase C isozymes and the regulation of diverse cell responses. Am J Physiol Lung Cell Mol Physiol 279:L429-L438.
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.279
-
-
Dempsey, E.C.1
Newton, A.C.2
Mochly-Rosen, D.3
Fields, A.P.4
Reyland, M.E.5
Insel, P.A.6
Messing, R.O.7
-
13
-
-
14644414790
-
Protein kinase cascades in the regulation of cardiac hypertrophy
-
Dorn GW II, Force T. 2005. Protein kinase cascades in the regulation of cardiac hypertrophy. J Clin Invest 115:527-537.
-
(2005)
J Clin Invest
, vol.115
, pp. 527-537
-
-
Dorn II, G.W.1
Force, T.2
-
14
-
-
0036196195
-
Intracellular transport mechanisms of signal transducers
-
Dorn GW, Mochly-Rosen D. 2002. Intracellular transport mechanisms of signal transducers. Annu Rev Physiol 64:407-429.
-
(2002)
Annu Rev Physiol
, vol.64
, pp. 407-429
-
-
Dorn, G.W.1
Mochly-Rosen, D.2
-
15
-
-
0036351317
-
Analysis of gene function in somatic mammalian cells using small interfering RNAs
-
Elbashir SM, Harborth J, Weber K, Tuschl T. 2002. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26:199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
16
-
-
34250333339
-
Dose- and timedependent apoptotic effects by angiotensin II infusion on left ventricular cardiomyocytes
-
Fabris B, Candido R, Bortoletto M, Zentilin L, Sandri M, Fior F, Toffoli B, Stebel M, Bardelli M, Belgrado D, Giacca M, Carretta R. 2007. Dose- and timedependent apoptotic effects by angiotensin II infusion on left ventricular cardiomyocytes. J Hypertens 25:1481-1490.
-
(2007)
J Hypertens
, vol.25
, pp. 1481-1490
-
-
Fabris, B.1
Candido, R.2
Bortoletto, M.3
Zentilin, L.4
Sandri, M.5
Fior, F.6
Toffoli, B.7
Stebel, M.8
Bardelli, M.9
Belgrado, D.10
Giacca, M.11
Carretta, R.12
-
17
-
-
0035447723
-
c-Jun N-terminal kinase/interacting protein 1 inhibits gene expression in response to hypertrophic agonists in neonatal rat ventricular myocytes
-
Finn SG, Dickens M, Fuller SJ. 2001. c-Jun N-terminal kinase/interacting protein 1 inhibits gene expression in response to hypertrophic agonists in neonatal rat ventricular myocytes. Biochem J 358:489-495.
-
(2001)
Biochem J
, vol.358
, pp. 489-495
-
-
Finn, S.G.1
Dickens, M.2
Fuller, S.J.3
-
18
-
-
69549152502
-
PKC delta mediated GalphaQ stimulation of the ERK5 pathway plays a key role in cardiac hypertrophy
-
García-Hoz C, Herranz M, Teresa Díaz-Meco M, Moscat J, Ribas C, Mayor F, Jr. 2007. PKC delta mediated GalphaQ stimulation of the ERK5 pathway plays a key role in cardiac hypertrophy. J Mol Cell Cardiol 42:S37-S54.
-
(2007)
J Mol Cell Cardiol
, vol.42
-
-
García-Hoz, C.1
Herranz, M.2
Teresa Díaz-Meco, M.3
Moscat, J.4
Ribas, C.5
Mayor Jr., F.6
-
20
-
-
0028030002
-
Increased protein kinase C and isozyme redistribution in pressure-overload cardiac hypertrophy in the rat
-
Gu X, Bishop SP. 1994. Increased protein kinase C and isozyme redistribution in pressure-overload cardiac hypertrophy in the rat. Circ Res 75:926-931.
-
(1994)
Circ Res
, vol.75
, pp. 926-931
-
-
Gu, X.1
Bishop, S.P.2
-
21
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
Joerg H, Jeffery DM. 2006. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 7:589-600.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 589-600
-
-
Joerg, H.1
Jeffery, D.M.2
-
23
-
-
0035141474
-
Simvastatin inhibits noradrenaline-induced hypertrophy of cultured neonatal rat cardiomyocytes
-
Luo JD, Xie F, Zhang WW, Ma XD, Guan JX, Chen X. 2001. Simvastatin inhibits noradrenaline-induced hypertrophy of cultured neonatal rat cardiomyocytes. Br J Pharmacol 132:159-164.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 159-164
-
-
Luo, J.D.1
Xie, F.2
Zhang, W.W.3
Ma, X.D.4
Guan, J.X.5
Chen, X.6
-
24
-
-
33846362954
-
Angiotensin II cell signaling: Physiological and pathological effects in the cardiovascular system
-
Mehta PK, Griendling KK. 2007. Angiotensin II cell signaling: Physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol 292:C82-C97.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Mehta, P.K.1
Griendling, K.K.2
-
25
-
-
33846121333
-
Vascular cell senescence: Contribution to atherosclerosis
-
Minamino T, Komuro I. 2007. Vascular cell senescence: Contribution to atherosclerosis. Circ Res 100(1): 15-26.
-
(2007)
Circ Res
, vol.100
, Issue.1
, pp. 15-26
-
-
Minamino, T.1
Komuro, I.2
-
26
-
-
33751226264
-
Contractile effects of angiotensin and endothelin in failing and non-failing human hearts
-
Mollmann H, Schmidt-Schweda S, Nef H, Mollmann S, Burtsin JV, Klose S, Elsässer A, Holubarsch CJ. 2007. Contractile effects of angiotensin and endothelin in failing and non-failing human hearts. Int J Cardiol 114:34-40.
-
(2007)
Int J Cardiol
, vol.114
, pp. 34-40
-
-
Mollmann, H.1
Schmidt-Schweda, S.2
Nef, H.3
Mollmann, S.4
Burtsin, J.V.5
Klose, S.6
Elsässer, A.7
Holubarsch, C.J.8
-
27
-
-
0002514316
-
The role of protein kinase C in cellular proliferation and cell cycle control
-
Parker PJ, Dekker L, editors, Austin, Texas, USA: Landes. pp
-
Murray NR, Thompson LJ, Fields AP. 1997. The role of protein kinase C in cellular proliferation and cell cycle control. In: Parker PJ, Dekker L, editors. Molecular biology intelligence unit. Austin, Texas, USA: Landes. pp 97-120.
-
(1997)
Molecular biology intelligence unit
, pp. 97-120
-
-
Murray, N.R.1
Thompson, L.J.2
Fields, A.P.3
-
28
-
-
0034575441
-
From the sarcomere to the nucleus: Role of genetics and signaling in structural heart disease
-
Nicol RL, Frey N, Olson EN. 2000. From the sarcomere to the nucleus: Role of genetics and signaling in structural heart disease. Annu Rev Genomics Hum Genet 1:179-223.
-
(2000)
Annu Rev Genomics Hum Genet
, vol.1
, pp. 179-223
-
-
Nicol, R.L.1
Frey, N.2
Olson, E.N.3
-
29
-
-
33747792064
-
MAPK signalling: ERK5 versus ERK1/2
-
Nishimoto S, Nishida E. 2006. MAPK signalling: ERK5 versus ERK1/2. EMBO Rep 7:782-786.
-
(2006)
EMBO Rep
, vol.7
, pp. 782-786
-
-
Nishimoto, S.1
Nishida, E.2
-
30
-
-
47749127695
-
Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein (CREB)-Ser133 phosphorylation in the heart
-
Ozgen N, Obreztchikova M, Guo J, Elouardighi H, Dorn GW II, Wilson BA, Steinberg SF. 2008. Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein (CREB)-Ser133 phosphorylation in the heart. J Biol Chem 283:17009-17019.
-
(2008)
J Biol Chem
, vol.283
, pp. 17009-17019
-
-
Ozgen, N.1
Obreztchikova, M.2
Guo, J.3
Elouardighi, H.4
Dorn II, G.W.5
Wilson, B.A.6
Steinberg, S.F.7
-
31
-
-
0033811089
-
Angiotensin II-induced cardiac hypertrophy is associated with different mitogenactivated protein kinase activation in normotensive and hypertensive mice
-
Pellieux C, Sauthier T, Aubert JF, Brunner HR, Pedrazzini T. 2000. Angiotensin II-induced cardiac hypertrophy is associated with different mitogenactivated protein kinase activation in normotensive and hypertensive mice. J Hypertens 18:1307-1317.
-
(2000)
J Hypertens
, vol.18
, pp. 1307-1317
-
-
Pellieux, C.1
Sauthier, T.2
Aubert, J.F.3
Brunner, H.R.4
Pedrazzini, T.5
-
32
-
-
0034460132
-
Proteasomemediated degradation of the coactivator p300 impairs cardiac transcription
-
Poizat C, Sartorelli V, Chung G, Kloner RA, Kedes L. 2000. Proteasomemediated degradation of the coactivator p300 impairs cardiac transcription. Mol Cell Biol 20:8643-8654.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8643-8654
-
-
Poizat, C.1
Sartorelli, V.2
Chung, G.3
Kloner, R.A.4
Kedes, L.5
-
33
-
-
2342424738
-
MEK5 and ERK5 are localized in the nuclei of resting as well as stimulated cells, while MEKK2 translocates from the cytosol to the nucleus upon stimulation
-
Raviv Z, Kalie E, Seger R. 2004. MEK5 and ERK5 are localized in the nuclei of resting as well as stimulated cells, while MEKK2 translocates from the cytosol to the nucleus upon stimulation. J Cell Sci 117:1773-1784.
-
(2004)
J Cell Sci
, vol.117
, pp. 1773-1784
-
-
Raviv, Z.1
Kalie, E.2
Seger, R.3
-
34
-
-
0037047109
-
Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects
-
Regan CP, Li W, Boucher DM, Spatz S, Su MS, Kuida K. 2002. Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects. Proc Natl Acad Sci USA 99:9248-9253.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9248-9253
-
-
Regan, C.P.1
Li, W.2
Boucher, D.M.3
Spatz, S.4
Su, M.S.5
Kuida, K.6
-
35
-
-
0141616595
-
Protein kinase C isoform-selective signals that lead to cardiac hypertrophy and the progression of heart failure
-
Sabri A, Steinberg SF. 2003. Protein kinase C isoform-selective signals that lead to cardiac hypertrophy and the progression of heart failure. Mol Cell Biochem 251:97-101.
-
(2003)
Mol Cell Biochem
, vol.251
, pp. 97-101
-
-
Sabri, A.1
Steinberg, S.F.2
-
36
-
-
50549105060
-
Angiotensin II: A hormone involved in and contributing to pro-hypertrophic cardiac networks and target of antihypertrophic cross-talks
-
Schlüter KD, Wenzel S. 2008. Angiotensin II: A hormone involved in and contributing to pro-hypertrophic cardiac networks and target of antihypertrophic cross-talks. Pharmacol Ther 119:311-325.
-
(2008)
Pharmacol Ther
, vol.119
, pp. 311-325
-
-
Schlüter, K.D.1
Wenzel, S.2
-
37
-
-
33846782998
-
Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells
-
Sharma G, Goalstone ML. 2007. Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells. Biochem Biophys Res Commun 354:1078-1083.
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 1078-1083
-
-
Sharma, G.1
Goalstone, M.L.2
-
38
-
-
42249089860
-
System-level investigation into the regulatory mechanism of the calcineurin/NFAT signaling pathway
-
Shin SY, Yang JM, Choo SM, Kwon KS, Cho KH. 2008. System-level investigation into the regulatory mechanism of the calcineurin/NFAT signaling pathway. Cell Signal 20:1117-1124.
-
(2008)
Cell Signal
, vol.20
, pp. 1117-1124
-
-
Shin, S.Y.1
Yang, J.M.2
Choo, S.M.3
Kwon, K.S.4
Cho, K.H.5
-
39
-
-
55949109631
-
Structural basis of protein kinase C isoform function
-
Steinberg SF. 2008. Structural basis of protein kinase C isoform function. Physiol Rev 88:1341-1378.
-
(2008)
Physiol Rev
, vol.88
, pp. 1341-1378
-
-
Steinberg, S.F.1
-
40
-
-
77749243124
-
-
Takahashi N, Saito Y, Kuwahara K, Harada M, Tanimoto K, Nakagawa Y, Kawakami R, Nakanishi M, Yasuno S, Usami S, Yoshimura A, Nakao K. 2005.
-
(2005)
-
-
Takahashi, N.1
Saito, Y.2
Kuwahara, K.3
Harada, M.4
Tanimoto, K.5
Nakagawa, Y.6
Kawakami, R.7
Nakanishi, M.8
Yasuno, S.9
Usami, S.10
Yoshimura, A.11
Nakao, K.12
-
41
-
-
19944380417
-
-
Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes. J Mol Cell Cardiol 38:185-192.
-
Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes. J Mol Cell Cardiol 38:185-192.
-
-
-
-
42
-
-
0034705485
-
Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy
-
Takeishi Y, Ping P, Bolli R, Kirkpatrick DL, Hoit BD, Walsh RA. 2000. Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy. Circ Res 86(12): 1218-1223.
-
(2000)
Circ Res
, vol.86
, Issue.12
, pp. 1218-1223
-
-
Takeishi, Y.1
Ping, P.2
Bolli, R.3
Kirkpatrick, D.L.4
Hoit, B.D.5
Walsh, R.A.6
-
43
-
-
0036762815
-
Recent advances in angiotensin II signaling
-
Touyz RM, Berry C. 2002. Recent advances in angiotensin II signaling. Braz J Med Biol Res 35:1001-1015.
-
(2002)
Braz J Med Biol Res
, vol.35
, pp. 1001-1015
-
-
Touyz, R.M.1
Berry, C.2
-
44
-
-
4544315655
-
Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5
-
Vega RB, Harrison BC, Meadows E, Roberts CR, Papst PJ, Olson EN, McKinsey TA. 2004. Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Mol Cell Biol 24:8374-8385.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8374-8385
-
-
Vega, R.B.1
Harrison, B.C.2
Meadows, E.3
Roberts, C.R.4
Papst, P.J.5
Olson, E.N.6
McKinsey, T.A.7
-
45
-
-
34548695952
-
Mitogen-activated protein kinases in heart development and diseases
-
Wang Y. 2007. Mitogen-activated protein kinases in heart development and diseases. Circulation 116:1413-1423.
-
(2007)
Circulation
, vol.116
, pp. 1413-1423
-
-
Wang, Y.1
-
46
-
-
32144436881
-
Regulation of cellular functions by the ERK5 signalling pathway
-
Wang X, Tournier C. 2006. Regulation of cellular functions by the ERK5 signalling pathway. Cell Signal 18:753-760.
-
(2006)
Cell Signal
, vol.18
, pp. 753-760
-
-
Wang, X.1
Tournier, C.2
-
47
-
-
0032489550
-
Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells
-
Wang Y, Su B, Sah VP, Brown JH, Han J, Chien KR. 1998. Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells. J Biol Chem 273:5423-5426.
-
(1998)
J Biol Chem
, vol.273
, pp. 5423-5426
-
-
Wang, Y.1
Su, B.2
Sah, V.P.3
Brown, J.H.4
Han, J.5
Chien, K.R.6
-
48
-
-
19944383095
-
Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway
-
Wang X, Merritt AJ, Seyfried J, Guo C, Papadakis ES, Finegan KG, Kayahara M, Dixon J, Boot- Handford RP, Cartwright EJ, Mayer U, Tournier C. 2005. Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway. Mol Cell Biol 25:336-345.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 336-345
-
-
Wang, X.1
Merritt, A.J.2
Seyfried, J.3
Guo, C.4
Papadakis, E.S.5
Finegan, K.G.6
Kayahara, M.7
Dixon, J.8
Boot- Handford, R.P.9
Cartwright, E.J.10
Mayer, U.11
Tournier, C.12
-
49
-
-
0035815665
-
Activation of a C-terminal transcriptional activation domain of ERK5 by autophosphorylation
-
Yan C, Luo H, Lee JD, Abe J, Berk BC. 2001. Activation of a C-terminal transcriptional activation domain of ERK5 by autophosphorylation. J Biol Chem 276:10870-10878.
-
(2001)
J Biol Chem
, vol.276
, pp. 10870-10878
-
-
Yan, C.1
Luo, H.2
Lee, J.D.3
Abe, J.4
Berk, B.C.5
-
50
-
-
2942717178
-
Knockout of ERK5 causes multiple defects in placental and embryonic development
-
Yan L, Carr J, Ashby PR, Murry-Tait V, Thompson C, Arthur JS. 2003. Knockout of ERK5 causes multiple defects in placental and embryonic development. BMC Dev Biol 3:11.
-
(2003)
BMC Dev Biol
, vol.3
, pp. 11
-
-
Yan, L.1
Carr, J.2
Ashby, P.R.3
Murry-Tait, V.4
Thompson, C.5
Arthur, J.S.6
-
51
-
-
14044263017
-
Yan Establishing a murine pancreatic cancer CaSm model: Up-regulation of CaSm is required for the transformed phenotype of murine pancreatic adenocarcinoma
-
Yan Y, Rubinchik S, Watson PM, Kelley JR, Fraser MM, Wood AL, Dong JY, Gillanders WE, Boylan AM, Watson DK, Cole DJ. 2005. Yan Establishing a murine pancreatic cancer CaSm model: up-regulation of CaSm is required for the transformed phenotype of murine pancreatic adenocarcinoma. Mol Ther 11:363-372.
-
(2005)
Mol Ther
, vol.11
, pp. 363-372
-
-
Yan, Y.1
Rubinchik, S.2
Watson, P.M.3
Kelley, J.R.4
Fraser, M.M.5
Wood, A.L.6
Dong, J.Y.7
Gillanders, W.E.8
Boylan, A.M.9
Watson, D.K.10
Cole, D.J.11
-
52
-
-
29444433258
-
Mechanical stretchinduced hypertrophy of neonatal rat ventricular myocytes is mediated by β(1)-integrin-microtubule signalling pathways
-
Yutao X, Geru W, Xiaojun B, Tao G, Aquin M. 2006. Mechanical stretchinduced hypertrophy of neonatal rat ventricular myocytes is mediated by β(1)-integrin-microtubule signalling pathways. Eur J Heart Fail 8: 16-22.
-
(2006)
Eur J Heart Fail
, vol.8
, pp. 16-22
-
-
Yutao, X.1
Geru, W.2
Xiaojun, B.3
Tao, G.4
Aquin, M.5
-
53
-
-
24644482721
-
Ets-1 is a critical regulator of Ang II-mediated vascular inflammation and remodeling
-
Zhan Y, Brown C, Maynard E, Anshelevich A, Ni W, Ho IC, Oettgen P. 2005. Ets-1 is a critical regulator of Ang II-mediated vascular inflammation and remodeling. J Clin Invest 115:2508-2516.
-
(2005)
J Clin Invest
, vol.115
, pp. 2508-2516
-
-
Zhan, Y.1
Brown, C.2
Maynard, E.3
Anshelevich, A.4
Ni, W.5
Ho, I.C.6
Oettgen, P.7
-
54
-
-
59349104358
-
Activation of ERK5 in angiotensin II-induced hypertrophy of human aortic smooth muscle cells
-
Zhao Z, Geng J, Ge Z, Wang W, Zhang Y, Kang W. 2009. Activation of ERK5 in angiotensin II-induced hypertrophy of human aortic smooth muscle cells. Mol Cell Biochem 322:171-178.
-
(2009)
Mol Cell Biochem
, vol.322
, pp. 171-178
-
-
Zhao, Z.1
Geng, J.2
Ge, Z.3
Wang, W.4
Zhang, Y.5
Kang, W.6
-
55
-
-
38949114588
-
Propofol depresses angiotensin II-induced cardiomyocyte hypertrophy in vitro
-
Zou XJ, Yang L, Yao SL. 2008. Propofol depresses angiotensin II-induced cardiomyocyte hypertrophy in vitro. Exp Biol Med (Maywood) 233:200-208
-
(2008)
Exp Biol Med (Maywood)
, vol.233
, pp. 200-208
-
-
Zou, X.J.1
Yang, L.2
Yao, S.L.3
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