In vivo evaluation of α7 nicotinic acetylcholine receptor agonists [11C]A-582941 and [11C]A-844606 in mice and conscious monkeys

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Toyohara, Jun ^a,b   Ishiwata, Kiichi ^b   Sakata, Muneyuki ^b   Wu, Jin ^a   Nishiyama, Shingo ^c   Tsukada, Hideo ^c   Hashimoto, Kenji ^a  

^a CHIBA UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^c Central Research Laboratory   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAZABICYCLO[3.2.2]NONANE 4 CARBOXYLIC ACID 4 BROMOPHENYL ESTER; A 582941; A 582941 C 11; A 844606; A 844606 C 11; BUNGAROTOXIN RECEPTOR; TRACER; UNCLASSIFIED DRUG; 2 (5 METHYLHEXAHYDROPYRROLO(3,4 C)PYRROL 2 YL)XANTHEN 9 ONE; 2-(5-METHYLHEXAHYDROPYRROLO(3,4-C)PYRROL-2-YL)XANTHEN-9-ONE; A-582941; CARBON; NICOTINIC AGENT; NICOTINIC RECEPTOR; PYRIDAZINE DERIVATIVE; PYRROLE DERIVATIVE; RADIOPHARMACEUTICAL AGENT; XANTHONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CEREBELLUM; CLINICAL EVALUATION; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; IN VIVO STUDY; METHYLATION; MONKEY; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; THALAMUS; TISSUE DISTRIBUTION; ANIMAL; CHEMICAL MODEL; CHEMICAL STRUCTURE; CONSCIOUSNESS; HAPLORHINI; MALE; METABOLISM; METHODOLOGY; SCINTISCANNING; SYNTHESIS;

MUS; PRIMATES;

ANIMALS; BRAIN; CARBON RADIOISOTOPES; CONSCIOUSNESS; HAPLORHINI; MALE; MICE; MODELS, CHEMICAL; MOLECULAR STRUCTURE; NICOTINIC AGONISTS; POSITRON-EMISSION TOMOGRAPHY; PYRIDAZINES; PYRROLES; RADIOPHARMACEUTICALS; RECEPTORS, NICOTINIC; TISSUE DISTRIBUTION; XANTHONES;

EID: 77749337516     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008961     Document Type: Article

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