Evaluation of in vivo selective binding of [11C]doxepin to histamine H1 receptors in five animal species

Nuclear Medicine and Biology

Volumn 31, Issue 4, 2004, Pages 493-502

  Ishiwata, Kiichi ^a   Kawamura, Kazunori ^a,b   Wang, Wei Fang ^a   Tsukada, Hideo ^c   Harada, Norihiro ^c   Mochizuki, Hideki ^d   Kimura, Yuichi ^a   Ishii, Kenji ^a   Iwata, Ren ^e   Yanai, Kazuhiko ^d  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b 141 0032   (Japan)

^c CENTRAL RESEARCH LABORATORY   (Japan)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e TOHOKU UNIVERSITY   (Japan)

Author keywords

11C doxepin; Histamine H1 receptor; Positron emission tomography

Indexed keywords

CHLORPHENIRAMINE; DOXEPIN; DOXEPIN C 11; HISTAMINE H1 RECEPTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H2 RECEPTOR ANTAGONIST; HISTAMINE H3 RECEPTOR ANTAGONIST; MEPYRAMINE; THIOPERAMIDE; TRACER; UNCLASSIFIED DRUG; ZOLANTIDINE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN MAPPING; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG METABOLISM; GUINEA PIG; HUMAN; MACACA; MALE; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RABBIT; RAT; RECEPTOR BINDING;

ANIMALS; BRAIN; CARBON RADIOISOTOPES; DOXEPIN; GUINEA PIGS; HISTAMINE AGONISTS; HUMANS; MACACA MULATTA; MALE; METABOLIC CLEARANCE RATE; MICE; PROTEIN BINDING; RABBITS; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; RECEPTORS, HISTAMINE H1; SPECIES SPECIFICITY; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 11144354698     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2003.11.005     Document Type: Article

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