Transgene-mediated GDNF expression enhances synaptic connectivity and GABA transmission to improve functional outcome after spinal cord contusion

Journal of Neurochemistry

Volumn 113, Issue 1, 2010, Pages 143-152

  Koelsch, Angela ^a   Feng, Yongjia ^a   Fink, David J ^a   Mata, Marina ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Extracellular signal related kinase; Gamma amino butyric acid; Gene therapy; Glial cell line derived neurotrophic factor; Herpes simplex virus; Spinal cord injury

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; RECOMBINANT PROTEIN; SYNAPSIN I; SYNAPTOPHYSIN; UO 126; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLUNT TRAUMA; CONTROLLED STUDY; CONTUSION; CONVALESCENCE; FEMALE; GABAERGIC TRANSMISSION; HERPES SIMPLEX VIRUS; LOCOMOTION; NERVE FIBER GROWTH; NERVE SPROUTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD; SPINAL CORD INJURY; SPINAL CORD NERVE CELL; THORACOLUMBAR SPINE; TRANSGENE;

ANALYSIS OF VARIANCE; ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; FEMALE; GAMMA-AMINOBUTYRIC ACID; GENE THERAPY; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GLUTAMATE DECARBOXYLASE; GREEN FLUORESCENT PROTEINS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MOTOR ACTIVITY; NEUROFILAMENT PROTEINS; NEURONS; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SPINAL CORD; SPINAL CORD INJURIES; SYNAPTIC TRANSMISSION;

SIMPLEXVIRUS;

EID: 77749271026     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06593.x     Document Type: Article

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