γ-aminobutyric acid inhibits synergistic interleukin-6 release but not transcriptional activation in astrocytoma cells

NeuroImmunoModulation

Volumn 15, Issue 2, 2008, Pages 117-124

  Roach Jr , Joseph D ^a   Aguinaldo, Grant T ^a   Jonnalagadda, Kaumudi ^b   Hughes Jr , Francis M ^b   Spangelo, Bryan L ^a  

^a UNIVERSITY OF NEVADA   (United States)

^b UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

Author keywords

Alzheimer disease; GABA; IL 1 ; IL 6; TNF

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 AMINOBUTYRIC ACID; COMPLEMENTARY DNA; CYTOKINE; I KAPPA B ALPHA; INTERLEUKIN 6; RECOMBINANT INTERLEUKIN 1BETA; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; RNA; SYNAPTOPHYSIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; ASTROCYTOMA CELL; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GLIOMA CELL; INFLAMMATION; NERVE CELL CULTURE; NEUROIMMUNOLOGY; NEUROTRANSMISSION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; ASTROCYTOMA; BRAIN NEOPLASMS; CELL LINE, TUMOR; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION REGULATION; I-KAPPA B PROTEINS; INTERLEUKIN-1BETA; INTERLEUKIN-6; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TUMOR NECROSIS FACTOR-ALPHA;

EID: 48449084185     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000148194     Document Type: Article

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