Mutant SOD1 knockdown in all cell types ameliorates disease in G85R SOD1 mice with a limited additional effect over knockdown restricted to motor neurons

Journal of Neurochemistry

Volumn 113, Issue 1, 2010, Pages 166-174

  Wang, Lijun ^a   Grisotti, Gabriella ^a   Roos, Raymond P ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Amyotrophic lateral sclerosis; Familial amyotrophic lateral sclerosis; Motor neuron; Neurodegeneration; Superoxide dismutase type 1

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; CRE RECOMBINASE; MESSENGER RNA; MUTANT PROTEIN; TAMOXIFEN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TYPE; CONTROLLED STUDY; DISEASE DURATION; GENE DELETION; GENE MUTATION; INTERNEURON; MOTONEURON; MOUSE; NONHUMAN; PATHOGENICITY; PRENATAL PERIOD; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ARGININE; DISEASE MODELS, ANIMAL; ESTROGEN ANTAGONISTS; GLYCINE; HUMANS; MICE; MICE, TRANSGENIC; MOTOR NEURONS; MUTATION; RNA, MESSENGER; SPINAL CORD; SUPEROXIDE DISMUTASE; TAMOXIFEN; TIME FACTORS;

MUS; MUS MUSCULUS;

EID: 77749264823     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06594.x     Document Type: Article

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