Aberrant sphingomyelin/ceramide metabolic-induced neuronal endosomal/lysosomal dysfunction: Potential pathological consequences in age-related neurodegeneration

Advanced Drug Delivery Reviews

Volumn 55, Issue 11, 2003, Pages 1515-1524

  Soreghan, Brian ^a   Thomas, Stefani N ^a   Yang, Austin J ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; A ; Ceramide; Endocytosis; Lysosomes; Sphingomyelin

Indexed keywords

CELLS; DISEASES; LIPIDS; METABOLISM; PATHOLOGY; POLYPEPTIDES;

ENDOCYTIC FUNCTIONS; VESICULAR TRANSPORT;

DRUG INFUSION;

AMYLOID; CERAMIDE; LIPOFUSCIN; SPHINGOLIPID; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE;

AGING; ALZHEIMER DISEASE; CATABOLISM; CELL ACTIVITY; CELL MEMBRANE TRANSPORT; ENDOSOME; HUMAN; LIPID STORAGE; LYSOSOME; LYSOSOME STORAGE DISEASE; MEMBRANE FORMATION; MEMBRANE FUSION; MEMBRANE STRUCTURE; NERVE CELL DEGENERATION; NERVE DEGENERATION; NEUROTOXICITY; PRIORITY JOURNAL; REVIEW;

EID: 0345714776     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2003.07.007     Document Type: Article

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