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Volumn 25, Issue 1, 2010, Pages 65-73

Efficient inhibition of non-small-cell lung cancer xenograft by systemic delivery of plasmid-encoding short-hairpin RNA targeting VEGF

Author keywords

Angiogenesis; Non small cell lung cancer (NSCL)Capoptosis; RNA interference; Vascular endothelial growth factor (VEGF)

Indexed keywords

CD31 ANTIGEN; CYCLINE; SHORT HAIRPIN RNA; VASCULOTROPIN; SMALL INTERFERING RNA;

EID: 77649330574     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.2009.0692     Document Type: Article
Times cited : (16)

References (44)
  • 2
    • 0037606097 scopus 로고    scopus 로고
    • Chemotherapy for non-small-cell lung cancer. Part 1: Early-stage disease
    • Novello S, Le Chevalier T. Chemotherapy for non-small-cell lung cancer. Part 1: Early-stage disease. Oncology (Williston Park) 2003;17:357.
    • (2003) Oncology (Williston Park) , vol.17 , pp. 357
    • Novello, S.1    Le Chevalier, T.2
  • 3
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and meta-stasis
    • Folkman J. Role of angiogenesis in tumor growth and meta-stasis. Semin Oncol 2002;29(6 Suppl 16):15.
    • (2002) Semin Oncol , vol.29 , Issue.6 SUPPL. 16 , pp. 15
    • Folkman, J.1
  • 4
    • 0035062394 scopus 로고    scopus 로고
    • The splice variants of vascular endothelial growth factor (VEGF) and their receptors
    • Robinson CJ, Stringer SE. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J Cell Sci 2001;114(Pt 5):853.
    • (2001) J Cell Sci , vol.114 , Issue.PART 5 , pp. 853
    • Robinson, C.J.1    Stringer, S.E.2
  • 5
    • 0032400862 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hemato-poietic lineages in vivo
    • Gabrilovich D, Ishida T, Oyama T, et al. Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hemato-poietic lineages in vivo. Blood 1998;92:4150.
    • (1998) Blood , vol.92 , pp. 4150
    • Gabrilovich, D.1    Ishida, T.2    Oyama, T.3
  • 6
    • 0034929216 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells
    • Pidgeon GP, Barr MP, Harmey JH, et al. Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells. Br J Cancer 2001;85:273.
    • (2001) Br J Cancer , vol.85 , pp. 273
    • Pidgeon, G.P.1    Barr, M.P.2    Harmey, J.H.3
  • 7
    • 0029793371 scopus 로고    scopus 로고
    • During angiogen-esis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium
    • Melder RJ, Koenig GC, Witwer BP, et al. During angiogen-esis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium. Nat Med. 1996;2:992.
    • (1996) Nat Med , vol.2 , pp. 992
    • Melder, R.J.1    Koenig, G.C.2    Witwer, B.P.3
  • 8
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Basic science and clinical progress
    • Ferrara N. Vascular endothelial growth factor: Basic science and clinical progress. Endocr Rev 2004;25:581.
    • (2004) Endocr Rev , vol.25 , pp. 581
    • Ferrara, N.1
  • 9
    • 3242700400 scopus 로고    scopus 로고
    • The prognostic significance of vascular endothelial growth factor levels in sera of non-small-cell lung cancer patients
    • Kaya A, Ciledag A, Gulbay BE, et al. The prognostic significance of vascular endothelial growth factor levels in sera of non-small-cell lung cancer patients. Respir Med 2004;98:632.
    • (2004) Respir Med , vol.98 , pp. 632
    • Kaya, A.1    Ciledag, A.2    Gulbay, B.E.3
  • 10
    • 0034693631 scopus 로고    scopus 로고
    • Correlation of total VEGF mRNA and protein expression with histologic type, tumor angiogenesis, patient survival, and timing of relapse in nonsmall-cell lung cancer
    • Yuan A, Yu CJ, Chen WJ, et al. Correlation of total VEGF mRNA and protein expression with histologic type, tumor angiogenesis, patient survival, and timing of relapse in nonsmall-cell lung cancer. Int J Cancer 2000;89:475.
    • (2000) Int J Cancer , vol.89 , pp. 475
    • Yuan, A.1    Yu, C.J.2    Chen, W.J.3
  • 11
    • 19844380545 scopus 로고    scopus 로고
    • Role of serum vascular endothelial growth factor in the prediction of angiogenesis and prognosis for non-small-cell lung cancer
    • Shimanuki Y, Takahashi K, Cui R, et al. Role of serum vascular endothelial growth factor in the prediction of angiogenesis and prognosis for non-small-cell lung cancer. Lung 2005;183:29.
    • (2005) Lung , vol.183 , pp. 29
    • Shimanuki, Y.1    Takahashi, K.2    Cui, R.3
  • 12
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon GJ. RNA interference. Nature 2002;418:244.
    • (2002) Nature , vol.418 , pp. 244
    • Hannon, G.J.1
  • 13
    • 33645167401 scopus 로고    scopus 로고
    • Prospects of RNA interference therapy for cancer
    • Pai SI, Lin YY, Macaes B, et al. Prospects of RNA interference therapy for cancer. Gene Ther 2006;13:464.
    • (2006) Gene Ther , vol.13 , pp. 464
    • Pai, S.I.1    Lin, Y.Y.2    Macaes, B.3
  • 14
    • 4644350944 scopus 로고    scopus 로고
    • Unlocking the potential of the human genome with RNA interference
    • Hannon GJ, Rossi JJ. Unlocking the potential of the human genome with RNA interference. Nature 2004;431:371.
    • (2004) Nature , vol.431 , pp. 371
    • Hannon, G.J.1    Rossi, J.J.2
  • 15
    • 0038748037 scopus 로고    scopus 로고
    • Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model
    • Reich SJ, Fosnot J, Kuroki A, et al. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol Vis 2003;9:210.
    • (2003) Mol Vis , vol.9 , pp. 210
    • Reich, S.J.1    Fosnot, J.2    Kuroki, A.3
  • 16
    • 34447272949 scopus 로고    scopus 로고
    • VEGF promotes tumori-genesis and angiogenesis of human glioblastoma stem cells
    • Oka N, Soeda A, Inagaki A, et al. VEGF promotes tumori-genesis and angiogenesis of human glioblastoma stem cells. Biochem Biophys Res Commun 2007;360:553.
    • (2007) Biochem Biophys Res Commun , vol.360 , pp. 553
    • Oka, N.1    Soeda, A.2    Inagaki, A.3
  • 17
    • 51749085556 scopus 로고    scopus 로고
    • Vesicular stomatitis virus matrix protein gene enhances the antitumor effects of radi-ation via induction of apoptosis
    • Du XB, Lang JY, Xu JR, et al. Vesicular stomatitis virus matrix protein gene enhances the antitumor effects of radi-ation via induction of apoptosis. Apoptosis 2008;13:1205.
    • (2008) Apoptosis , vol.13 , pp. 1205
    • Du, X.B.1    Lang, J.Y.2    Xu, J.R.3
  • 18
    • 0037050352 scopus 로고    scopus 로고
    • Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
    • Schiller JH, Harrington D, Belani CP, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. NE JM 2002;346:92.
    • (2002) NE JM , vol.346 , pp. 92
    • Schiller, J.H.1    Harrington, D.2    Belani, C.P.3
  • 19
    • 2342557044 scopus 로고    scopus 로고
    • Targeted therapies for non-small-cell lung cancer: Biology, rationale, and preclini-cal results from a radiation oncology perspective
    • Raben D, Helfrich B, Bunn PA, Jr. Targeted therapies for non-small-cell lung cancer: Biology, rationale, and preclini-cal results from a radiation oncology perspective. Int J Ra-diat Oncol Biol Phys 2004;59(2 Suppl):27.
    • (2004) Int J Ra-diat Oncol Biol Phys , vol.59 , Issue.2 SUPPL. , pp. 27
    • Raben, D.1    Helfrich, B.2    Bunn Jr., P.A.3
  • 21
    • 0035422178 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is an autocrine survival factor for neuropilinexpressing breast carcinoma cells
    • Bachelder RE, Crago A, Chung J, et al. Vascular endothelial growth factor is an autocrine survival factor for neuropilinexpressing breast carcinoma cells. Cancer Res 2001;61:5736.
    • (2001) Cancer Res , vol.61 , pp. 5736
    • Bachelder, R.E.1    Crago, A.2    Chung, J.3
  • 22
    • 0036468930 scopus 로고    scopus 로고
    • A potential autocrine role for vascular endothelial growth factor in prostate cancer
    • Jackson MW, Roberts JS, Heckford SE, et al. A potential autocrine role for vascular endothelial growth factor in prostate cancer. Cancer Res 2002;62:854.
    • (2002) Cancer Res , vol.62 , pp. 854
    • Jackson, M.W.1    Roberts, J.S.2    Heckford, S.E.3
  • 23
    • 0034807692 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Acting as an autocrine growth factor for human gastric adenocarcinoma cell MGC803
    • Tian X, Song S, Wu J, et al. Vascular endothelial growth factor: Acting as an autocrine growth factor for human gastric adenocarcinoma cell MGC803. Biochem Biophys Res Commun 2001;286:505.
    • (2001) Biochem Biophys Res Commun , vol.286 , pp. 505
    • Tian, X.1    Song, S.2    Wu, J.3
  • 24
    • 34247468303 scopus 로고    scopus 로고
    • The potential of antiangiogenic therapy in nonsmall-cell lung cancer
    • Giaccone G. The potential of antiangiogenic therapy in nonsmall-cell lung cancer. Clin Cancer Res 2007;13:1961.
    • (2007) Clin Cancer Res , vol.13 , pp. 1961
    • Giaccone, G.1
  • 25
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an antivascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta LG, Chen H, O'Connor SJ, et al. Humanization of an antivascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 1997;57:4593.
    • (1997) Cancer Res , vol.57 , pp. 4593
    • Presta, L.G.1    Chen, H.2    O'Connor, S.J.3
  • 26
    • 0033231069 scopus 로고    scopus 로고
    • Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis
    • Shaheen RM, Davis DW, Liu W, et al. Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis. Cancer Res 1999;59:5412.
    • (1999) Cancer Res , vol.59 , pp. 5412
    • Shaheen, R.M.1    Davis, D.W.2    Liu, W.3
  • 27
  • 28
    • 13144262858 scopus 로고    scopus 로고
    • Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate
    • Goldman CK, Kendall RL, Cabrera G, et al. Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. Proc Natl Acad Sci U S A 1998;95:8795.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8795
    • Goldman, C.K.1    Kendall, R.L.2    Cabrera, G.3
  • 29
    • 0035049240 scopus 로고    scopus 로고
    • Endogenous angiogenesis inhibitors and their therapeutic implications
    • Cao Y. Endogenous angiogenesis inhibitors and their therapeutic implications. Int J Biochem Cell Biol 2001;33:357.
    • (2001) Int J Biochem Cell Biol , vol.33 , pp. 357
    • Cao, Y.1
  • 30
    • 27944490875 scopus 로고    scopus 로고
    • VEGF as a therapeutic target in cancer
    • Ferrara N. VEGF as a therapeutic target in cancer. Oncology 2005;69(Suppl 3):11.
    • (2005) Oncology , vol.69 , Issue.SUPPL. 3 , pp. 11
    • Ferrara, N.1
  • 31
    • 0032542528 scopus 로고    scopus 로고
    • Gene therapy strategies for tumor antiangiogenesis
    • Kong HL, Crystal RG. Gene therapy strategies for tumor antiangiogenesis. J Natl Cancer Inst 1998;90:273.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 273
    • Kong, H.L.1    Crystal, R.G.2
  • 32
    • 0027517321 scopus 로고
    • Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans
    • Nabel GJ, Nabel EG, Yang Z-Y, et al. Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans. PNAS 1993;90:11307.
    • (1993) PNAS , vol.90 , pp. 11307
    • Nabel, G.J.1    Nabel, E.G.2    Yang, Z.-Y.3
  • 33
    • 17644403503 scopus 로고    scopus 로고
    • A small interfering RNA targeting vascular endothelial growth factor inhibits Ewing's sarcoma growth in a xenograft mouse model
    • Guan H, Zhou Z, Wang H, et al. A small interfering RNA targeting vascular endothelial growth factor inhibits Ewing's sarcoma growth in a xenograft mouse model. Clin Cancer Res 2005;11:2662.
    • (2005) Clin Cancer Res , vol.11 , pp. 2662
    • Guan, H.1    Zhou, Z.2    Wang, H.3
  • 34
    • 33645886052 scopus 로고    scopus 로고
    • Short interfering RNA-mediated gene silencing of vascular endothelial growth factor: Effects on cellular proliferation in colon cancer cells
    • discussion, 374
    • Mulkeen AL, Silva T, Yoo PS, et al. Short interfering RNA-mediated gene silencing of vascular endothelial growth factor: Effects on cellular proliferation in colon cancer cells. Arch Surg 2006;141:367; discussion, 374.
    • (2006) Arch Surg , vol.141 , pp. 367
    • Mulkeen, A.L.1    Silva, T.2    Yoo, P.S.3
  • 35
    • 27644507359 scopus 로고    scopus 로고
    • Genomic analysis of anti-hepatitis B virus (HBV) activity by small interfering RNA and lamivudine in stable HBV-producing cells
    • Guo Y, Guo H, Zhang L, et al. Genomic analysis of anti-hepatitis B virus (HBV) activity by small interfering RNA and lamivudine in stable HBV-producing cells. J Virolo 2005;79:14392.
    • (2005) J Virolo , vol.79 , pp. 14392
    • Guo, Y.1    Guo, H.2    Zhang, L.3
  • 36
    • 0036877043 scopus 로고    scopus 로고
    • Cationic liposome-DNA complexes-lipoplexes for gene transfer and therapy
    • Zhdanov RI, Podobed OV, Vlassov VV. Cationic liposome-DNA complexes-lipoplexes for gene transfer and therapy. Bioelectrochemistry 2002;58:53.
    • (2002) Bioelectrochemistry , vol.58 , pp. 53
    • Zhdanov, R.I.1    Podobed, O.V.2    Vlassov, V.V.3
  • 37
    • 0035033843 scopus 로고    scopus 로고
    • The promise and potential hazards of adenovirus gene therapy
    • Young LS, Mautner V. The promise and potential hazards of adenovirus gene therapy. Gut 2001;48:733.
    • (2001) Gut , vol.48 , pp. 733
    • Young, L.S.1    Mautner, V.2
  • 38
    • 2942631177 scopus 로고    scopus 로고
    • Enhanced hepatitis C virus NS3 specific Th1 immune responses induced by codelivery of protein antigen and CpG with cationic liposomes
    • Jiao X, Wang RY, Qiu Q, et al. Enhanced hepatitis C virus NS3 specific Th1 immune responses induced by codelivery of protein antigen and CpG with cationic liposomes. J Gen Virol 2004;85(Pt 6):1545.
    • (2004) J Gen Virol , vol.85 , Issue.PART 6 , pp. 1545
    • Jiao, X.1    Wang, R.Y.2    Qiu, Q.3
  • 39
    • 0029964866 scopus 로고    scopus 로고
    • Mechanism of oligonucleotide re-lease from cationic liposomes
    • Zelphati O, Szoka FC, Jr. Mechanism of oligonucleotide re-lease from cationic liposomes. Proc Natl Acad Sci U S A 1996;93:11493.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11493
    • Zelphati, O.1    Szoka Jr., F.C.2
  • 40
    • 0032440716 scopus 로고    scopus 로고
    • Incorporation rates, stabilities, cytotoxicities, and release of liposomal tetracy-cline and doxycycline in human serum
    • Sangare L, Morisset R, Omri A, et al. Incorporation rates, stabilities, cytotoxicities, and release of liposomal tetracy-cline and doxycycline in human serum. J Antimicrob Che-mother 1998;42:831.
    • (1998) J Antimicrob Che-mother , vol.42 , pp. 831
    • Sangare, L.1    Morisset, R.2    Omri, A.3
  • 41
    • 0028855939 scopus 로고
    • Sphingomyelin-cholesterol liposomes significantly enhance the pharmaco-kinetic and therapeutic properties of vincristine in murine and human tumour models
    • Webb MS, Harasym TO, Masin D, et al. Sphingomyelin-cholesterol liposomes significantly enhance the pharmaco-kinetic and therapeutic properties of vincristine in murine and human tumour models. Br J Cancer 1995;72:896.
    • (1995) Br J Cancer , vol.72 , pp. 896
    • Webb, M.S.1    Harasym, T.O.2    Masin, D.3
  • 42
    • 0029150245 scopus 로고
    • Vascular permeability in a human tumor xenograft: Molecular size dependence and cutoff size
    • Yuan F, Dellian M, Fukumura D, et al. Vascular permeability in a human tumor xenograft: Molecular size dependence and cutoff size. Cancer Res 1995;55:3752.
    • (1995) Cancer Res , vol.55 , pp. 3752
    • Yuan, F.1    Dellian, M.2    Fukumura, D.3
  • 43
    • 13744249482 scopus 로고    scopus 로고
    • DOTAP (and other cationic liposomes): Chemistry, biophysics, and transfection
    • Simberg D, Weisman S, Talmon Y, et al. DOTAP (and other cationic liposomes): Chemistry, biophysics, and transfection. Crit Rev Ther Drug Carrier Syst 2004;21:257.
    • (2004) Crit Rev Ther Drug Carrier Syst , vol.21 , pp. 257
    • Simberg, D.1    Weisman, S.2    Talmon, Y.3
  • 44
    • 0034634861 scopus 로고    scopus 로고
    • Comprehensive analysis of the acute toxicities induced by systemic administration of cationic liposome:plasmid DNA complexes in mice
    • Tousignant JD, Gates AL, Ingram LA, et al. Comprehensive analysis of the acute toxicities induced by systemic administration of cationic liposome:plasmid DNA complexes in mice. Hum Gene Ther 2000;11:2493.
    • (2000) Hum Gene Ther , vol.11 , pp. 2493
    • Tousignant, J.D.1    Gates, A.L.2    Ingram, L.A.3


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