Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay

BMC Biochemistry

Volumn 11, Issue 1, 2010, Pages

  Bobenchik, April M ^a,b   Choi, Jae Yeon ^c   Mishra, Arunima ^b   Rujan, Iulian N ^b   Hao, Bing ^b   Voelker, Dennis R ^c   Hoch, Jeffrey C ^b   Mamoun, Choukri ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; CETRIMIDE; DODECYLTRIMETHYLAMMONIUM; PHOSPHATIDYLCHOLINE; PHOSPHOETHANOLAMINE; PHOSPHOETHANOLAMINE METHYLTRANSFERASE; UNCLASSIFIED DRUG; ENZYME INHIBITOR; HISTAMINE METHYLTRANSFERASE; METHYLTRANSFERASE; QUATERNARY AMMONIUM DERIVATIVE;

ARTICLE; DRUG INHIBITION; ENZYME ASSAY; ENZYME COUPLED METHYLATION ASSAY; HUMAN; IN VITRO SELECTION; LIPOGENESIS; NUCLEAR MAGNETIC RESONANCE; PLASMODIUM FALCIPARUM; YEAST; ANIMAL; BINDING SITE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; METABOLISM; METHYLATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN TERTIARY STRUCTURE;

ANURA; NEMATODA; PLASMODIUM FALCIPARUM; PROTOZOA;

AMODIAQUINE; ANIMALS; BINDING SITES; CETRIMONIUM COMPOUNDS; ENZYME ASSAYS; ENZYME INHIBITORS; HISTAMINE N-METHYLTRANSFERASE; MAGNETIC RESONANCE SPECTROSCOPY; METHYLATION; METHYLTRANSFERASES; PLASMODIUM FALCIPARUM; PROTEIN STRUCTURE, TERTIARY; QUATERNARY AMMONIUM COMPOUNDS;

EID: 77649288041     PISSN: None     EISSN: 14712091     Source Type: Journal    
DOI: 10.1186/1471-2091-11-4     Document Type: Article

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