-
1
-
-
40849097408
-
The intrinsic contributions of tyrosine, serine, glycine and arginine to the affinity and specificity of antibodies
-
Birtalan S., Zhang Y., Fellouse F.A., Shao L., Schaefer G., Sidhu S.S. The intrinsic contributions of tyrosine, serine, glycine and arginine to the affinity and specificity of antibodies. J. Mol. Biol. 2008, 377:1518.
-
(2008)
J. Mol. Biol.
, vol.377
, pp. 1518
-
-
Birtalan, S.1
Zhang, Y.2
Fellouse, F.A.3
Shao, L.4
Schaefer, G.5
Sidhu, S.S.6
-
2
-
-
0032479179
-
Anatomy of hot spots in protein interfaces
-
Bogan A.A., Thorn K.S. Anatomy of hot spots in protein interfaces. J. Mol. Biol. 1998, 280:1.
-
(1998)
J. Mol. Biol.
, vol.280
, pp. 1
-
-
Bogan, A.A.1
Thorn, K.S.2
-
3
-
-
2942748131
-
A carbohydrate binding module as a diversity-carrying scaffold
-
Cicortas Gunnarsson L., Nordberg Karlsson E., Albrekt A.S., Andersson M., Holst O., Ohlin M. A carbohydrate binding module as a diversity-carrying scaffold. Prot. Eng. Des. Sel. 2004, 17:213.
-
(2004)
Prot. Eng. Des. Sel.
, vol.17
, pp. 213
-
-
Cicortas Gunnarsson, L.1
Nordberg Karlsson, E.2
Albrekt, A.S.3
Andersson, M.4
Holst, O.5
Ohlin, M.6
-
4
-
-
0033593356
-
Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire
-
de Wildt R.M.T., Hoet R.M.A., van Venrooij W.J., Tomlinson I.M., Winter G. Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire. J. Mol. Biol. 1999, 285:895.
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 895
-
-
de Wildt, R.M.T.1
Hoet, R.M.A.2
van Venrooij, W.J.3
Tomlinson, I.M.4
Winter, G.5
-
5
-
-
0037227517
-
Biophysical properties of human antibody variable domains
-
Ewert S., Huber T., Honegger A., Plückthun A. Biophysical properties of human antibody variable domains. J. Mol. Biol. 2003, 325:531.
-
(2003)
J. Mol. Biol.
, vol.325
, pp. 531
-
-
Ewert, S.1
Huber, T.2
Honegger, A.3
Plückthun, A.4
-
6
-
-
34848848421
-
High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries
-
Fellouse F.A., Esaki K., Birtalan S., Raptis D., Cancasci V.J., Koide A., Jhurani P., Vasser M., Wiesmann C., Kossiakoff A.A., Koide S., Sidhu S.S. High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries. J. Mol. Biol. 2007, 373:924.
-
(2007)
J. Mol. Biol.
, vol.373
, pp. 924
-
-
Fellouse, F.A.1
Esaki, K.2
Birtalan, S.3
Raptis, D.4
Cancasci, V.J.5
Koide, A.6
Jhurani, P.7
Vasser, M.8
Wiesmann, C.9
Kossiakoff, A.A.10
Koide, S.11
Sidhu, S.S.12
-
7
-
-
12344271184
-
On the salt-induced stabilization of pair and many-body hydrophobic interactions
-
Ghosh T., Kalra A., Garde S. On the salt-induced stabilization of pair and many-body hydrophobic interactions. J. Phys. Chem. B 2005, 109:642.
-
(2005)
J. Phys. Chem. B
, vol.109
, pp. 642
-
-
Ghosh, T.1
Kalra, A.2
Garde, S.3
-
8
-
-
0031392356
-
H CDR2 are sufficient to generate or enhance the specificity of two forms of an anti-arsonate antibody variable region for DNA
-
H CDR2 are sufficient to generate or enhance the specificity of two forms of an anti-arsonate antibody variable region for DNA. Mol. Immunol. 1997, 34:1281.
-
(1997)
Mol. Immunol.
, vol.34
, pp. 1281
-
-
Hande, S.1
Manser, T.2
-
9
-
-
0024246956
-
Surface, subunit interfaces and interior of oligomeric proteins
-
Janin J., Miller S., Chothia C. Surface, subunit interfaces and interior of oligomeric proteins. J. Mol. Biol. 1988, 204:155.
-
(1988)
J. Mol. Biol.
, vol.204
, pp. 155
-
-
Janin, J.1
Miller, S.2
Chothia, C.3
-
10
-
-
0032581610
-
Exploiting sequence space: shuffling in vivo formed complementarity determining regions into a master framework
-
Jirholt P., Ohlin M., Borrebaeck C.A.K., Söderlind E. Exploiting sequence space: shuffling in vivo formed complementarity determining regions into a master framework. Gene 1998, 215:471.
-
(1998)
Gene
, vol.215
, pp. 471
-
-
Jirholt, P.1
Ohlin, M.2
Borrebaeck, C.A.K.3
Söderlind, E.4
-
11
-
-
33845971497
-
Using phage display to select antibodies recognizing post-translational modifications independently of sequence context
-
Kehoe J.W., Velappan N., Walbolt M., Rasmussen J., King D., Lou J., Knopp K., Pavlik P., Marks J.D., Bertozzi C.R., Bradbury A.R. Using phage display to select antibodies recognizing post-translational modifications independently of sequence context. Mol. Cell. Proteomics 2006, 5:2350.
-
(2006)
Mol. Cell. Proteomics
, vol.5
, pp. 2350
-
-
Kehoe, J.W.1
Velappan, N.2
Walbolt, M.3
Rasmussen, J.4
King, D.5
Lou, J.6
Knopp, K.7
Pavlik, P.8
Marks, J.D.9
Bertozzi, C.R.10
Bradbury, A.R.11
-
12
-
-
0034635335
-
Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides
-
Knappik A., Ge L., Honegger A., Pack P., Fischer M., Wellnhofer G., Hoess A., Wölle J., Plückthun A., Virnekäs B. Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides. J. Mol. Biol. 2000, 296:57.
-
(2000)
J. Mol. Biol.
, vol.296
, pp. 57
-
-
Knappik, A.1
Ge, L.2
Honegger, A.3
Pack, P.4
Fischer, M.5
Wellnhofer, G.6
Hoess, A.7
Wölle, J.8
Plückthun, A.9
Virnekäs, B.10
-
13
-
-
60749090900
-
Stabilization and humanization of a single-chain Fv antibody fragment specific for human lymphocyte antigen CD19 by designed point mutations and CDR-grafting onto a human framework
-
Kügler M., Stein C., Schwenkert M., Saul D., Vockentanz L., Huber T., Wetzel S.K., Scholz O., Plückthun A., Honegger A., Fey G.H. Stabilization and humanization of a single-chain Fv antibody fragment specific for human lymphocyte antigen CD19 by designed point mutations and CDR-grafting onto a human framework. Protein Eng. Des. Sel. 2009, 22:135.
-
(2009)
Protein Eng. Des. Sel.
, vol.22
, pp. 135
-
-
Kügler, M.1
Stein, C.2
Schwenkert, M.3
Saul, D.4
Vockentanz, L.5
Huber, T.6
Wetzel, S.K.7
Scholz, O.8
Plückthun, A.9
Honegger, A.10
Fey, G.H.11
-
14
-
-
58149380165
-
Chemical and genetic wrappers for improved phage and RNA display
-
Lamboy J.A., Tam P.Y., Lee L.S., Jackson P.J., Avrantinis S.K., Lee H.J., Corn R.M., Weiss G.A. Chemical and genetic wrappers for improved phage and RNA display. Chem. Bio. Chem. 2008, 9:2846.
-
(2008)
Chem. Bio. Chem.
, vol.9
, pp. 2846
-
-
Lamboy, J.A.1
Tam, P.Y.2
Lee, L.S.3
Jackson, P.J.4
Avrantinis, S.K.5
Lee, H.J.6
Corn, R.M.7
Weiss, G.A.8
-
15
-
-
0037160031
-
Functional consequences of insertions and deletions in the complementarity determining regions of human antibodies
-
Lantto J., Ohlin M. Functional consequences of insertions and deletions in the complementarity determining regions of human antibodies. J. Biol. Chem. 2002, 277:45108.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45108
-
-
Lantto, J.1
Ohlin, M.2
-
16
-
-
0037212339
-
IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains
-
Lefranc M.P., Pommié C., Ruiz M., Giudicelli V., Foulquier E., Truong L., Thouvenin-Contet V., Lefranc G. IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains. Dev. Comp. Immunol. 2003, 27:55.
-
(2003)
Dev. Comp. Immunol.
, vol.27
, pp. 55
-
-
Lefranc, M.P.1
Pommié, C.2
Ruiz, M.3
Giudicelli, V.4
Foulquier, E.5
Truong, L.6
Thouvenin-Contet, V.7
Lefranc, G.8
-
17
-
-
0035400341
-
Antibodies in haystacks: how selection strategy influences the outcome of selection from molecular diversity libraries
-
Lou J., Marzari R., Verzillo V., Ferrero F., Pak D., Sheng M., Yang C., Sblattero D., Bradbury A. Antibodies in haystacks: how selection strategy influences the outcome of selection from molecular diversity libraries. J. Immunol. Methods 2001, 253:233.
-
(2001)
J. Immunol. Methods
, vol.253
, pp. 233
-
-
Lou, J.1
Marzari, R.2
Verzillo, V.3
Ferrero, F.4
Pak, D.5
Sheng, M.6
Yang, C.7
Sblattero, D.8
Bradbury, A.9
-
18
-
-
0028058295
-
Molecular models and structural comparisons of native and mutant class I filamentous bacteriophages Ff (fd, f1, M13), If1 and IKe
-
Marvin D.A., Hale R.D., Nave C., Helmer-Citterich M. Molecular models and structural comparisons of native and mutant class I filamentous bacteriophages Ff (fd, f1, M13), If1 and IKe. J. Mol. Biol. 1994, 235:260.
-
(1994)
J. Mol. Biol.
, vol.235
, pp. 260
-
-
Marvin, D.A.1
Hale, R.D.2
Nave, C.3
Helmer-Citterich, M.4
-
19
-
-
58749083955
-
Automated identification of complementarity determining regions (CDRs) reveals peculiar characteristics of CDRs and B cell epitopes
-
Ofran Y., Schlessinger A., Rost B. Automated identification of complementarity determining regions (CDRs) reveals peculiar characteristics of CDRs and B cell epitopes. J. Immunol. 2008, 181:6230.
-
(2008)
J. Immunol.
, vol.181
, pp. 6230
-
-
Ofran, Y.1
Schlessinger, A.2
Rost, B.3
-
20
-
-
33344476078
-
Creating a focused antibody library for improved hapten recognition
-
Persson H., Lantto J., Ohlin M. Creating a focused antibody library for improved hapten recognition. J. Mol. Biol. 2006, 357:607.
-
(2006)
J. Mol. Biol.
, vol.357
, pp. 607
-
-
Persson, H.1
Lantto, J.2
Ohlin, M.3
-
21
-
-
0032555478
-
Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel
-
Pini A., Viti F., Santucci A., Carnemolla B., Zardi L., Neri P., Neri D. Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel. J. Biol. Chem. 1998, 273:21769.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21769
-
-
Pini, A.1
Viti, F.2
Santucci, A.3
Carnemolla, B.4
Zardi, L.5
Neri, P.6
Neri, D.7
-
22
-
-
0037103361
-
Genetic analysis of autoantibodies in idiopathic thrombocytopenic purpura reveals evidence of clonal expansion and somatic mutation
-
Roark J.H., Bussel J.B., Cines D.B., Siegel D.L. Genetic analysis of autoantibodies in idiopathic thrombocytopenic purpura reveals evidence of clonal expansion and somatic mutation. Blood 2002, 100:1388.
-
(2002)
Blood
, vol.100
, pp. 1388
-
-
Roark, J.H.1
Bussel, J.B.2
Cines, D.B.3
Siegel, D.L.4
-
23
-
-
58749114220
-
Engineering antibody heavy chain CDR3 to create a phage display Fab library rich in antibodies that bind charged carbohydrates
-
Schoonbroodt S., Steukers M., Viswanathan M., Frans N., Timmermans M., Wehnert A., Nguyen M., Ladner R.C., Hoet R.M. Engineering antibody heavy chain CDR3 to create a phage display Fab library rich in antibodies that bind charged carbohydrates. J. Immunol. 2008, 181:6213.
-
(2008)
J. Immunol.
, vol.181
, pp. 6213
-
-
Schoonbroodt, S.1
Steukers, M.2
Viswanathan, M.3
Frans, N.4
Timmermans, M.5
Wehnert, A.6
Nguyen, M.7
Ladner, R.C.8
Hoet, R.M.9
-
24
-
-
13144261717
-
Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens
-
Sheets M.D., Amersdorfer P., Finnern R., Sargent P., Lindquist E., Schier R., Hemingsen G., Wong C., Gerhart J.C., Marks J.D. Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:6157.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 6157
-
-
Sheets, M.D.1
Amersdorfer, P.2
Finnern, R.3
Sargent, P.4
Lindquist, E.5
Schier, R.6
Hemingsen, G.7
Wong, C.8
Gerhart, J.C.9
Marks, J.D.10
-
25
-
-
0033883409
-
Recombining germline-derived CDR-sequences for creating diverse single-framework antibody libraries
-
Söderlind E., Strandberg L., Jirholt P., Kobayashi N., Alexeiva V., Åberg A.M., Nilsson A., Jansson B., Ohlin M., Wingren C., Danielsson L., Carlsson R., Borrebaeck C.A.K. Recombining germline-derived CDR-sequences for creating diverse single-framework antibody libraries. Nat. Biotechnol. 2000, 18:852.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 852
-
-
Söderlind, E.1
Strandberg, L.2
Jirholt, P.3
Kobayashi, N.4
Alexeiva, V.5
Åberg, A.M.6
Nilsson, A.7
Jansson, B.8
Ohlin, M.9
Wingren, C.10
Danielsson, L.11
Carlsson, R.12
Borrebaeck, C.A.K.13
-
26
-
-
33745357168
-
Direct observation of salt effects on molecular interactions through explicit-solvent molecular dynamics simulations: differential effects on electrostatic and hydrophobic interactions and comparisons to Poisson-Boltzmann theory
-
Thomas A.S., Elcock A.H. Direct observation of salt effects on molecular interactions through explicit-solvent molecular dynamics simulations: differential effects on electrostatic and hydrophobic interactions and comparisons to Poisson-Boltzmann theory. J. Am. Chem. Soc. 2006, 128:7796.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 7796
-
-
Thomas, A.S.1
Elcock, A.H.2
-
27
-
-
9344223986
-
Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library
-
Vaughan T.J., Williams A.J., Pritchard K., Osbourn J.K., Pope A.R., Earnshaw J.C., McCafferty J., Hodits R.A., Wilton J., Johnson K.S. Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library. Nat. Biotechnol. 1996, 14:309.
-
(1996)
Nat. Biotechnol.
, vol.14
, pp. 309
-
-
Vaughan, T.J.1
Williams, A.J.2
Pritchard, K.3
Osbourn, J.K.4
Pope, A.R.5
Earnshaw, J.C.6
McCafferty, J.7
Hodits, R.A.8
Wilton, J.9
Johnson, K.S.10
-
28
-
-
0027380730
-
Efficient method for constructing comprehensive murine Fab antibody libraries displayed on phage
-
Ørum H., Andersen P.S., Øster A., Johansen L.K., Riise E., Bjørnvad M., Svendsen I., Engberg J. Efficient method for constructing comprehensive murine Fab antibody libraries displayed on phage. Nucleic Acids Res. 1993, 21:4491449.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 4491449
-
-
Ørum, H.1
Andersen, P.S.2
Øster, A.3
Johansen, L.K.4
Riise, E.5
Bjørnvad, M.6
Svendsen, I.7
Engberg, J.8
|