GABAA receptor subtype selectivity underlying anxiolytic effect of 6-hydroxyflavone

Biochemical Pharmacology

Volumn 79, Issue 9, 2010, Pages 1337-1344

  Ren, Lihuan ^a   Wang, Feng ^a   Xu, Zhiwen ^a   Chan, Wing Man ^a   Zhao, Cunyou ^a   Xue, Hong ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

6 Hydroxyflavone; Benzodiazepine; Flavonoids; GABAA receptor; Subtype selectivity

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 6 HYDROXYFLAVONE; BENZODIAZEPINE; DIAZEPAM; FLUMAZENIL; RECEPTOR SUBTYPE; RECOMBINANT RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; BINDING AFFINITY; BRAIN CELL; CELL STRAIN HEK293; CLONIC SEIZURE; COGNITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; EXPERIMENTAL TEST; GENE EXPRESSION; HOLE BOARD TEST; HORIZONTAL WIRE TEST; HUMAN; HUMAN CELL; MALE; MAZE TEST; MEMORY DISORDER; MOTOR COORDINATION; MOUSE; MUSCLE RELAXATION; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; PASSIVE AVOIDANCE; PATCH CLAMP; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; ROTAROD TEST; SEDATION; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ATAXIA; CELLS, CULTURED; FLAVONOIDS; FLUNITRAZEPAM; HUMANS; MALE; MEMORY; MICE; MICE, INBRED ICR; MOLECULAR STRUCTURE; NEURONS; RATS; RECEPTORS, GABA-A;

EID: 77649185632     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.12.024     Document Type: Article

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