Glycation of PDGF results in decreased biological activity

International Journal of Biochemistry and Cell Biology

Volumn 42, Issue 5, 2010, Pages 749-754

  Nass, Norbert ^a   Vogel, Katrin ^a   Hofmann, Britt ^a   Presek, Peter ^a   Silber, Rolf Edgar ^a   Simm, Andreas ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

AGEs; Diabetes; Fibroblast; Glyoxal; Methylglyoxal; PDGF

Indexed keywords

6 N CARBOXYMETHYLLYSINE; ADVANCED GLYCATION END PRODUCT; ALDEHYDE; ARGININE; CARBOHYDRATE; COLLAGEN; GLUCOSE; GLYOXAL; METHYLGLYOXAL; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR AB; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE B; PYRIMIDINE;

AGING; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; FIBROBLAST; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; OSTEOSARCOMA CELL; OXIDATION; PATHOPHYSIOLOGY; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN MODIFICATION; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; WESTERN BLOTTING; WOUND HEALING; WOUND HEALING IMPAIRMENT;

ANIMALS; BLOOD PLATELETS; CELL LINE; CELL PROLIFERATION; DIABETES MELLITUS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLYCOSYLATION; GLYCOSYLATION END PRODUCTS, ADVANCED; GLYOXAL; HUMANS; HYPERGLYCEMIA; MALE; MICE; MITOGENS; PHOSPHORYLATION; PILOT PROJECTS; PLATELET ACTIVATION; PLATELET-DERIVED GROWTH FACTOR; PROTEIN MULTIMERIZATION; PROTO-ONCOGENE PROTEINS C-AKT; PYRUVALDEHYDE; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 77649180502     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.01.012     Document Type: Article

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