Activator Gcn4 employs multiple segments of med15/Gal11, including the KIX domain, to recruit mediator to target genes in vivo

Journal of Biological Chemistry

Volumn 285, Issue 4, 2010, Pages 2438-2455

  Jedidi, Iness ^a   Zhang, Fan ^a   Qiu, Hongfang ^a   Stahl, Stephen J ^b   Palmer, Ira ^b   Kaufman, Joshua D ^b   Nadaud, Philippe S ^c   Mukherjee, Sujoy ^c   Wingfield, Paul T ^b   Jaroniec, Christopher P ^c   Hinnebusch, Alan G ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COACTIVATORS; CRITICAL DETERMINANT; IN-CELL; IN-VITRO; IN-VIVO; MULTISUBUNIT; NMR CHEMICAL SHIFTS; RNA POLYMERASE II; SUBDOMAIN; TARGET GENES; TRANSCRIPTIONAL ACTIVATIONS;

BINDING ENERGY; BINDING SITES; CHEMICAL ACTIVATION; MAMMALS; RNA; TARGETS;

EMPLOYMENT;

PROTEIN ARG1; PROTEIN GAL11; PROTEIN KIX; PROTEIN MED15; STEROID RECEPTOR COACTIVATOR 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GCN4; UNCLASSIFIED DRUG; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; GAL11 PROTEIN, S CEREVISIAE; GCN4 PROTEIN, S CEREVISIAE; MEDIATOR COMPLEX; PROTEIN SUBUNIT; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CONTROLLED STUDY; FUNGAL STRAIN; GENE TARGETING; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; AMINO ACID SEQUENCE; CHEMISTRY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE;

MAMMALIA;

AMINO ACID SEQUENCE; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CONSERVED SEQUENCE; GENE EXPRESSION REGULATION, FUNGAL; MEDIATOR COMPLEX; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHENOTYPE; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION, GENETIC;

EID: 77449125295     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.071589     Document Type: Article

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