Exclusive association and simultaneous appearance of congophilic plaques and AT8-positive dystrophic neurites in Tg2576 mice suggest a mechanism of senile plaque formation and progression of neuritic dystrophy in Alzheimer's disease

Acta Neuropathologica

Volumn 108, Issue 5, 2004, Pages 435-442

  Noda Saita, Kyoko ^a   Terai, Kazuhiro ^a   Iwai, Akihiko ^a   Tsukamoto, Mina ^a   Shitaka, Yoshitsugu ^a   Kawabata, Shigeki ^a   Okada, Masamichi ^a   Yamaguchi, Tokio ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Alzheimer's disease; Congophilic plaque; Dystrophic neurite; Quantitative analysis; Tau

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; CONGO RED; SERINE; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE MUTATION; GENE OVEREXPRESSION; HIPPOCAMPUS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL LESION; NEURITE; NEUROPATHOLOGY; NONHUMAN; PLAQUE FORMING CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; SENILE PLAQUE;

AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; CONGO RED; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; NEURITES; SENILE PLAQUES; TAU PROTEINS;

EID: 7744243271     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-004-0907-2     Document Type: Article

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