메뉴 건너뛰기




Volumn 148, Issue 1, 1996, Pages 259-265

Amyloid β protein deposition in normal aging has the same characteristics as that in Alzheimer's disease: Predominance of Aβ42(43) and association of Aβ40 with cored plaques

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN;

EID: 0030064140     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (111)

References (41)
  • 1
    • 0025753852 scopus 로고
    • The molecular pathology of Alzheimer's disease
    • Selkoe DJ: The molecular pathology of Alzheimer's disease Neuron 1991, 6:487-498
    • (1991) Neuron , vol.6 , pp. 487-498
    • Selkoe, D.J.1
  • 3
    • 0024343222 scopus 로고
    • Cerebral amyloidosis, aging and Alzheimer disease: A contribution from studies on Down's syndrome
    • Mann DMA Cerebral amyloidosis, aging and Alzheimer disease: a contribution from studies on Down's syndrome. Neurobiol Aging 1989, 10.397-399
    • (1989) Neurobiol Aging , vol.10 , pp. 397-399
    • Mann, D.M.A.1
  • 5
    • 0026907151 scopus 로고
    • A pathogenetic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid
    • Mullan M, Crawford F, Axelman K, Houlden H, Lilius L, Winblad B, Lannfelt L. A pathogenetic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid Nature Genet 1992, 1.354-347
    • (1992) Nature Genet , vol.1 , pp. 354-1347
    • Mullan, M.1    Crawford, F.2    Axelman, K.3    Houlden, H.4    Lilius, L.5    Winblad, B.6    Lannfelt, L.7
  • 6
    • 0024232950 scopus 로고
    • Protein chemical and immunocytochemical studies of meningovascular β-amyloid protein in Alzheimer's disease and normal aging
    • Joachim CL, Duffy LK, Morris JH, Selkoe DJ Protein chemical and immunocytochemical studies of meningovascular β-amyloid protein in Alzheimer's disease and normal aging. Brain Res 1988, 474:100-111
    • (1988) Brain Res , vol.474 , pp. 100-111
    • Joachim, C.L.1    Duffy, L.K.2    Morris, J.H.3    Selkoe, D.J.4
  • 7
    • 0026794746 scopus 로고
    • Mass spectrometry of purified amyloid β protein in Alzheimer's disease
    • Mori H, Takio K, Ogawara M, Selkoe DJ: Mass spectrometry of purified amyloid β protein in Alzheimer's disease. J Biol Chem 1992, 267.17082-17086
    • (1992) J Biol Chem , vol.267 , pp. 17082-17086
    • Mori, H.1    Takio, K.2    Ogawara, M.3    Selkoe, D.J.4
  • 9
    • 0027332081 scopus 로고
    • β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: Implications for the pathology of Alzheimer disease
    • Roher AE, Lowenson JD, Clarke S, Wood AS, Cotter RJ, Gowing E, Ball MJ. β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease. Proc Natl Acad Sci USA 1993, 90:10836-10840
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10836-10840
    • Roher, A.E.1    Lowenson, J.D.2    Clarke, S.3    Wood, A.S.4    Cotter, R.J.5    Gowing, E.6    Ball, M.J.7
  • 12
    • 0028322017 scopus 로고
    • An increased percentage of long amyloid β protein is secreted by familial amyloid β protein precursor (β APP717) mutants
    • Suzuki N, Cheung TT, Cai X-D, Odaka A, Otvos L Jr, Eckman C, Golde TE, Younkin SG: An increased percentage of long amyloid β protein is secreted by familial amyloid β protein precursor (β APP717) mutants Science 1994, 264:1336-1340
    • (1994) Science , vol.264 , pp. 1336-1340
    • Suzuki, N.1    Cheung, T.T.2    Cai, X.-D.3    Odaka, A.4    Otvos Jr., L.5    Eckman, C.6    Golde, T.E.7    Younkin, S.G.8
  • 13
    • 0027258525 scopus 로고
    • The carboxyl terminus of the β amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
    • Jarrett JT, Berger EP, Lansbury PT Jr: The carboxyl terminus of the β amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease Biochemistry 1993, 32:4693-4697
    • (1993) Biochemistry , vol.32 , pp. 4693-4697
    • Jarrett, J.T.1    Berger, E.P.2    Lansbury Jr., P.T.3
  • 14
    • 0028169925 scopus 로고
    • Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals, evidence that an initially deposited species is Aβ42(43)
    • Iwatsubo T, Odaka A, Suzuki N, Mizusawa H, Nukina N, Ihara Y: Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals, evidence that an initially deposited species is Aβ42(43) Neuron 1994, 13:45-53
    • (1994) Neuron , vol.13 , pp. 45-53
    • Iwatsubo, T.1    Odaka, A.2    Suzuki, N.3    Mizusawa, H.4    Nukina, N.5    Ihara, Y.6
  • 15
    • 0028919919 scopus 로고
    • Amyloid β-protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in Down's syndrome
    • Iwatsubo T, Mann DMA, Odaka A, Suzuki N, Ihara Y: Amyloid β-protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in Down's syndrome. Ann Neurol 1995, 37.294-299
    • (1995) Ann Neurol , vol.37 , pp. 294-299
    • Iwatsubo, T.1    Mann, D.M.A.2    Odaka, A.3    Suzuki, N.4    Ihara, Y.5
  • 16
    • 0014326852 scopus 로고
    • Observations on the brains of non-demented old people
    • Tomlinson BE, Blessed G, Roth M: Observations on the brains of non-demented old people J Neurol Sci 1968, 7.331-356
    • (1968) J Neurol Sci , vol.7 , pp. 331-356
    • Tomlinson, B.E.1    Blessed, G.2    Roth, M.3
  • 17
    • 0023225114 scopus 로고
    • The topographic distribution of senile plaques and neurofibrillary tangles in the brains of non-demented persons of different ages
    • Mann DMA, Tucker CM, Yates, PO: The topographic distribution of senile plaques and neurofibrillary tangles in the brains of non-demented persons of different ages. Neuropathol Appl Neurobiol 1987, 13:123-139
    • (1987) Neuropathol Appl Neurobiol , vol.13 , pp. 123-139
    • Mann, D.M.A.1    Tucker, C.M.2    Yates, P.O.3
  • 19
    • 0023905906 scopus 로고
    • Clinical, pathological, and neurochemical changes in dementia a subgroup with preserved mental status and numerous neocortical plaques
    • Katzman R, Terry R, DeTeresa R, Brown T, Davies P, Fuld P, Renbing X, Peck A Clinical, pathological, and neurochemical changes in dementia a subgroup with preserved mental status and numerous neocortical plaques Ann Neurol 1988, 23.138-144
    • (1988) Ann Neurol , vol.23 , pp. 138-144
    • Katzman, R.1    Terry, R.2    DeTeresa, R.3    Brown, T.4    Davies, P.5    Fuld, P.6    Renbing, X.7    Peck, A.8
  • 20
    • 0026743110 scopus 로고
    • Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease
    • Arriagada PV, Marzloff K, Hyman BT. Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease. Neurology 1992, 42:1681-1688
    • (1992) Neurology , vol.42 , pp. 1681-1688
    • Arriagada, P.V.1    Marzloff, K.2    Hyman, B.T.3
  • 21
    • 0027490070 scopus 로고
    • The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution
    • Hyman BT, Marzloff K, Arriagada PV: The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution J Neuropathol Exp Neurol 1993, 52.594-600
    • (1993) J Neuropathol Exp Neurol , vol.52 , pp. 594-600
    • Hyman, B.T.1    Marzloff, K.2    Arriagada, P.V.3
  • 22
    • 0027195933 scopus 로고
    • Seeding "one-dimensional crystallization" of amyloid- A pathogenic mechanism in Alzheimer's disease and scrapie?
    • Jarrett JT, Lansbury PT Jr: Seeding "one-dimensional crystallization" of amyloid- a pathogenic mechanism in Alzheimer's disease and scrapie? Cell 1993, 73:1055-1058
    • (1993) Cell , vol.73 , pp. 1055-1058
    • Jarrett, J.T.1    Lansbury Jr., P.T.2
  • 23
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan E: Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34.939-944
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.6
  • 24
    • 0022414054 scopus 로고
    • Diagnosis of Alzheimer's disease
    • Khachaturian ZS. Diagnosis of Alzheimer's disease Arch Neurol 1985, 42 1097-1104
    • (1985) Arch Neurol , vol.42 , pp. 1097-1104
    • Khachaturian, Z.S.1
  • 28
    • 0023809230 scopus 로고
    • Alzheimer's disease A double-labeling immunohistochemical study of senile plaques
    • Dickson DW, Farlo J, Davies P, Crystal H, Fuld P, Yen S-H: Alzheimer's disease A double-labeling immunohistochemical study of senile plaques Am J Pathol 1988, 132:86-101
    • (1988) Am J Pathol , vol.132 , pp. 86-101
    • Dickson, D.W.1    Farlo, J.2    Davies, P.3    Crystal, H.4    Fuld, P.5    Yen, S.-H.6
  • 29
    • 0024393488 scopus 로고
    • About the presence of paired helical filaments in dystrophic neurites participating in the plaque formation
    • Barcikowska M, Wisniewski HM, Bancher C, Grundke-Iqbal I: About the presence of paired helical filaments in dystrophic neurites participating in the plaque formation. Acta Neuropathol 1989, 78.225-231
    • (1989) Acta Neuropathol , vol.78 , pp. 225-231
    • Barcikowska, M.1    Wisniewski, H.M.2    Bancher, C.3    Grundke-Iqbal, I.4
  • 30
    • 0024369521 scopus 로고
    • Increased tau accumulation in senile plaques as a hallmark in Alzheimer's disease
    • Shin R-W, Ogomori K, Kitamoto T, Tateishi J: Increased tau accumulation in senile plaques as a hallmark in Alzheimer's disease Am J Pathol 1989, 134.1365-1371
    • (1989) Am J Pathol , vol.134 , pp. 1365-1371
    • Shin, R.-W.1    Ogomori, K.2    Kitamoto, T.3    Tateishi, J.4
  • 32
    • 0027118303 scopus 로고
    • Coenzyme Q10, iron, and vitamin B6 in genetically-confirmed Aizheimer's disease
    • Imagawa M, Naruse S, Tsuji S, Fujioka A, Yamaguchi H: Coenzyme Q10, iron, and vitamin B6 in genetically-confirmed Aizheimer's disease Lancet 1992, 340.671
    • (1992) Lancet , vol.340 , pp. 671
    • Imagawa, M.1    Naruse, S.2    Tsuji, S.3    Fujioka, A.4    Yamaguchi, H.5
  • 33
    • 0027956675 scopus 로고
    • High tissue content of soluble β1-40 is linked to cerebral amyloid angiopathy
    • Suzuki N, Iwatsubo T, Odaka A, Ishibashi Y, Kitada C, Ihara Y High tissue content of soluble β1-40 is linked to cerebral amyloid angiopathy. Am J Pathol 1994, 145:452-460
    • (1994) Am J Pathol , vol.145 , pp. 452-460
    • Suzuki, N.1    Iwatsubo, T.2    Odaka, A.3    Ishibashi, Y.4    Kitada, C.5    Ihara, Y.6
  • 34
    • 0023390305 scopus 로고
    • Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids
    • Kitamoto T, Ogomori K, Tateishi J, Prusiner SB Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids. Lab Invest 1987, 57:230-236
    • (1987) Lab Invest , vol.57 , pp. 230-236
    • Kitamoto, T.1    Ogomori, K.2    Tateishi, J.3    Prusiner, S.B.4
  • 35
    • 0023708239 scopus 로고
    • Massive somatodendritic sprouting of cortical neurons in Aizheimer's disease
    • Ihara Y. Massive somatodendritic sprouting of cortical neurons in Aizheimer's disease Brain Res 1988, 459: 138-144
    • (1988) Brain Res , vol.459 , pp. 138-144
    • Ihara, Y.1
  • 37
    • 0000074498 scopus 로고
    • The time course of pathological events in Down's syndrome with particular reference to the involvement of microglial cells and deposits of β/A4
    • Mann DMA, Younis N, Jones D, Stoddart RW: The time course of pathological events in Down's syndrome with particular reference to the involvement of microglial cells and deposits of β/A4. Neurodegeneration 1992, 1:201-215
    • (1992) Neurodegeneration , vol.1 , pp. 201-215
    • Mann, D.M.A.1    Younis, N.2    Jones, D.3    Stoddart, R.W.4
  • 39
    • 0029923520 scopus 로고    scopus 로고
    • Association of Aβ40-positive senile plaques with microglial cells in the brains of patients with Aizheimer's disease and in non-demented aged individuals
    • in press
    • Fukumoto H, Asami-Odaka A, Suzuki N, Iwatsubo T: Association of Aβ40-positive senile plaques with microglial cells in the brains of patients with Aizheimer's disease and in non-demented aged individuals Neurodegeneration (in press)
    • Neurodegeneration
    • Fukumoto, H.1    Asami-Odaka, A.2    Suzuki, N.3    Iwatsubo, T.4
  • 40
    • 0028863201 scopus 로고
    • Microglial cells and amyloid β protein (Aβ) deposition, association with Aβ40 containing plaques
    • Mann DMA, Iwatsubo T, Fukumoto H, Ihara Y, Odaka A, Suzuki N: Microglial cells and amyloid β protein (Aβ) deposition, association with Aβ40 containing plaques. Acta Neuropathol 1995;90:472-477
    • (1995) Acta Neuropathol , vol.90 , pp. 472-477
    • Mann, D.M.A.1    Iwatsubo, T.2    Fukumoto, H.3    Ihara, Y.4    Odaka, A.5    Suzuki, N.6
  • 41
    • 0025971426 scopus 로고
    • Apolipoprotein E immunoreactivity in cerebral amyloid deposits, and neurofibrillary tangles in Aizheimer's disease, and kuru plaque amyloid in Creutzfeldt-Jakob disease
    • Namba Y, Tomonaga M, Kawasaki H, Otomo E, Ikeda K: Apolipoprotein E immunoreactivity in cerebral amyloid deposits, and neurofibrillary tangles in Aizheimer's disease, and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res 1991, 541:163-166
    • (1991) Brain Res , vol.541 , pp. 163-166
    • Namba, Y.1    Tomonaga, M.2    Kawasaki, H.3    Otomo, E.4    Ikeda, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.