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Volumn 23, Issue 3, 2010, Pages 787-793

Effect of phytic acid and inositol on the proliferation and apoptosis of cells derived from colorectal carcinoma

Author keywords

Apoptosis; Colorectal cancer; Inositol; Phytic acid; Proliferation

Indexed keywords

CASPASE 3; INOSITOL; PHYTIC ACID;

EID: 77349115450     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or-00000699     Document Type: Article
Times cited : (35)

References (36)
  • 1
    • 0027442548 scopus 로고
    • Growth inhibition and differentiation of HT-29 cells in vitro by inositol hexaphosphate (phytic acid)
    • Sakamoto K, Venkatraman G and Shamsuddin AM: Growth inhibition and differentiation of HT-29 cells in vitro by inositol hexaphosphate (phytic acid). Carcinogenesis 14: 1815-1819, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 1815-1819
    • Sakamoto, K.1    Venkatraman, G.2    Shamsuddin, A.M.3
  • 2
    • 33947210819 scopus 로고    scopus 로고
    • Molecular mechanisms for the antitumor activity of inositol hexakisphosphate (IP6). Cancer Genomics
    • Bozsik A, Kokeny S and Olah E: Molecular mechanisms for the antitumor activity of inositol hexakisphosphate (IP6). Cancer Genomics Proteomics 4: 43-51, 2007.
    • (2007) Proteomics , vol.4 , pp. 43-51
    • Bozsik, A.1    Kokeny, S.2    Olah, E.3
  • 4
    • 0344244904 scopus 로고    scopus 로고
    • Inositol hexaphosphate (IP6) inhibits key events of cancer metastasis: I. In vitro studies of adhesion, migration and invasion of MDA-MB 231 human breast cancer cells
    • Tantivejkul K, Vucenik I and Shamsuddin AM: Inositol hexaphosphate (IP6) inhibits key events of cancer metastasis: I. In vitro studies of adhesion, migration and invasion of MDA-MB 231 human breast cancer cells. Anticancer Res 23: 3671-3679, 2003.
    • (2003) Anticancer Res , vol.23 , pp. 3671-3679
    • Tantivejkul, K.1    Vucenik, I.2    Shamsuddin, A.M.3
  • 5
    • 1642453720 scopus 로고    scopus 로고
    • In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: Induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor
    • Singh RP, Sharma G, Mallikarjuna GU, Dhanalakshmi S, Agarwal C and Agarwal R: In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor. Clin Cancer Res 10: 244-250, 2004.
    • (2004) Clin Cancer Res , vol.10 , pp. 244-250
    • Singh, R.P.1    Sharma, G.2    Mallikarjuna, G.U.3    Dhanalakshmi, S.4    Agarwal, C.5    Agarwal, R.6
  • 7
    • 35848947240 scopus 로고    scopus 로고
    • Molecular mechanism of inositol hexaphosphate-mediated apoptosis in human malignant glioblastoma T98G cells
    • Karmakar S, Banik NL and Ray SK: Molecular mechanism of inositol hexaphosphate-mediated apoptosis in human malignant glioblastoma T98G cells. Neurochem Res 32: 2094-2102, 2007.
    • (2007) Neurochem Res , vol.32 , pp. 2094-2102
    • Karmakar, S.1    Banik, N.L.2    Ray, S.K.3
  • 8
    • 24144458553 scopus 로고    scopus 로고
    • Inositol hexaphosphate-induced enhancement of natural killer cell activity correlates with suppression of colon carcinogenesis in rats
    • Zhang Z, Song Y and Wang XL: Inositol hexaphosphate-induced enhancement of natural killer cell activity correlates with suppression of colon carcinogenesis in rats. World J Gastroenterol 11: 5044-5046, 2005.
    • (2005) World J Gastroenterol , vol.11 , pp. 5044-5046
    • Zhang, Z.1    Song, Y.2    Wang, X.L.3
  • 9
    • 33748583748 scopus 로고    scopus 로고
    • Effects of inositol hexaphosphate on proliferation of HT-29 human colon carcinoma cell line
    • Tian Y and Song Y: Effects of inositol hexaphosphate on proliferation of HT-29 human colon carcinoma cell line. World J Gastroenterol 12: 4137-4142, 2006.
    • (2006) World J Gastroenterol , vol.12 , pp. 4137-4142
    • Tian, Y.1    Song, Y.2
  • 10
    • 0032217236 scopus 로고    scopus 로고
    • IP6 in treatment of liver cancer. I. IP6 inhibits growth and reverses transformed phenotype in HepG2 human liver cancer cell line
    • Vucenik I, Tantivejkul K, Zhang ZS, Cole KE, Saied I and Shamsuddin AM: IP6 in treatment of liver cancer. I. IP6 inhibits growth and reverses transformed phenotype in HepG2 human liver cancer cell line. Anticancer Res 18: 4083-4090, 1998.
    • (1998) Anticancer Res , vol.18 , pp. 4083-4090
    • Vucenik, I.1    Tantivejkul, K.2    Zhang, Z.S.3    Cole, K.E.4    Saied, I.5    Shamsuddin, A.M.6
  • 11
    • 0032217237 scopus 로고    scopus 로고
    • IP6 in treatment of liver cancer. II. Intra-tumoral injection of IP6 regresses pre-existing human liver cancer xenotransplanted in nude mice
    • Vucenik I, Zhang ZS and Shamsuddin AM: IP6 in treatment of liver cancer. II. Intra-tumoral injection of IP6 regresses pre-existing human liver cancer xenotransplanted in nude mice. Anticancer Res 18: 4091-4096, 1998.
    • (1998) Anticancer Res , vol.18 , pp. 4091-4096
    • Vucenik, I.1    Zhang, Z.S.2    Shamsuddin, A.M.3
  • 12
    • 0032787156 scopus 로고    scopus 로고
    • Mammary tumor inhibition by IP6: A review
    • Shamsuddin AM and Vucenik I: Mammary tumor inhibition by IP6: a review. Anticancer Res 19: 3671-3674, 1999.
    • (1999) Anticancer Res , vol.19 , pp. 3671-3674
    • Shamsuddin, A.M.1    Vucenik, I.2
  • 13
    • 0031856814 scopus 로고    scopus 로고
    • Novel anticancer function of inositol hexaphosphate: Inhibition of human rhabdomyosarcoma in vitro and in vivo
    • Vucenik I, Kalebic T, Tantivejkul K and Shamsuddin AM: Novel anticancer function of inositol hexaphosphate: inhibition of human rhabdomyosarcoma in vitro and in vivo. Anticancer Res 18: 1377-1384, 1998.
    • (1998) Anticancer Res , vol.18 , pp. 1377-1384
    • Vucenik, I.1    Kalebic, T.2    Tantivejkul, K.3    Shamsuddin, A.M.4
  • 16
    • 0031843738 scopus 로고    scopus 로고
    • Phytate, reactive oxygen species and colorectal cancer
    • Owen RW, Spiegelhalder B and Bartsch H: Phytate, reactive oxygen species and colorectal cancer. Eur J Cancer Prev 7 (Suppl 2): S41-S54, 1998.
    • (1998) Eur J Cancer Prev , vol.7 , Issue.SUPPL. 2
    • Owen, R.W.1    Spiegelhalder, B.2    Bartsch, H.3
  • 17
    • 0034746736 scopus 로고    scopus 로고
    • G0/G1 arrest and S phase inhibition of human cancer cell lines by inositol hexaphosphate (IP6)
    • El-Sherbiny YM, Cox MC, Ismail ZA, Shamsuddin AM and Vucenik I: G0/G1 arrest and S phase inhibition of human cancer cell lines by inositol hexaphosphate (IP6). Anticancer Res 21: 2393-2403, 2001.
    • (2001) Anticancer Res , vol.21 , pp. 2393-2403
    • El-Sherbiny, Y.M.1    Cox, M.C.2    Ismail, Z.A.3    Shamsuddin, A.M.4    Vucenik, I.5
  • 18
    • 0031858807 scopus 로고    scopus 로고
    • Up-regulation of the tumor suppressor gene p53 and WAF1 gene expression by IP6 in HT-29 human colon carcinoma cell line
    • Saied IT and Shamsuddin AM: Up-regulation of the tumor suppressor gene p53 and WAF1 gene expression by IP6 in HT-29 human colon carcinoma cell line. Anticancer Res 18: 1479-1484, 1998.
    • (1998) Anticancer Res , vol.18 , pp. 1479-1484
    • Saied, I.T.1    Shamsuddin, A.M.2
  • 20
    • 0024405693 scopus 로고
    • Inositol and inositol hexaphosphate suppress cell proliferation and tumor formation in CD-1 mice
    • Shamsuddin AM, Ullah A and Chakravarthy AK: Inositol and inositol hexaphosphate suppress cell proliferation and tumor formation in CD-1 mice. Carcinogenesis 10: 1461-1463, 1989.
    • (1989) Carcinogenesis , vol.10 , pp. 1461-1463
    • Shamsuddin, A.M.1    Ullah, A.2    Chakravarthy, A.K.3
  • 21
    • 0029057655 scopus 로고
    • Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer
    • Vucenik I, Yang GY and Shamsuddin AM: Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer. Carcinogenesis 16: 1055-1058, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 1055-1058
    • Vucenik, I.1    Yang, G.Y.2    Shamsuddin, A.M.3
  • 22
    • 0038732463 scopus 로고    scopus 로고
    • Phytic acid (IP6), novel broad spectrum anti-neoplastic agent: A systematic review
    • Fox CH and Eberl M: Phytic acid (IP6), novel broad spectrum anti-neoplastic agent: a systematic review. Complement Ther Med 10: 229-234, 2002.
    • (2002) Complement Ther Med , vol.10 , pp. 229-234
    • Fox, C.H.1    Eberl, M.2
  • 23
    • 0242526048 scopus 로고    scopus 로고
    • Cancer inhibition by inositol hexaphosphate (IP6) and inositol: From laboratory to clinic
    • Vucenik I and Shamsuddin AM: Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic. J Nutr 133: 3778S-3784S, 2003.
    • (2003) J Nutr , vol.133
    • Vucenik, I.1    Shamsuddin, A.M.2
  • 24
    • 18444363630 scopus 로고    scopus 로고
    • Dietary administration of inositol and/or inositol-6-phosphate prevents chemically-induced rat hepatocarcinogenesis
    • Lee HJ, Lee SA and Choi H: Dietary administration of inositol and/or inositol-6-phosphate prevents chemically-induced rat hepatocarcinogenesis. Asian Pac J Cancer Prev 6: 41-47, 2005.
    • (2005) Asian Pac J Cancer Prev , vol.6 , pp. 41-47
    • Lee, H.J.1    Lee, S.A.2    Choi, H.3
  • 25
    • 33750846875 scopus 로고    scopus 로고
    • Protection against cancer by dietary IP6 and inositol
    • Vucenik I and Shamsuddin AM: Protection against cancer by dietary IP6 and inositol. Nutr Cancer 55: 109-125, 2006.
    • (2006) Nutr Cancer , vol.55 , pp. 109-125
    • Vucenik, I.1    Shamsuddin, A.M.2
  • 26
    • 0030499776 scopus 로고    scopus 로고
    • Novel anti-cancer functions of IP6: Growth inhibition and differentiation of human mammary cancer cell lines in vitro
    • Shamsuddin AM, Yang GY and Vucenik I: Novel anti-cancer functions of IP6: growth inhibition and differentiation of human mammary cancer cell lines in vitro. Anticancer Res 16: 3287-3292, 1996.
    • (1996) Anticancer Res , vol.16 , pp. 3287-3292
    • Shamsuddin, A.M.1    Yang, G.Y.2    Vucenik, I.3
  • 27
    • 0037360095 scopus 로고    scopus 로고
    • Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: Modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes
    • Singh RP, Agarwal C and Agarwal R: Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes. Carcinogenesis 24: 555-563, 2003.
    • (2003) Carcinogenesis , vol.24 , pp. 555-563
    • Singh, R.P.1    Agarwal, C.2    Agarwal, R.3
  • 28
    • 3142745596 scopus 로고    scopus 로고
    • Growth inhibitory and apoptotic effects of inositol hexaphosphate in transgenic adenocarcinoma of mouse prostate (TRAMP-C1) cells
    • Sharma G, Singh RP and Agarwal R: Growth inhibitory and apoptotic effects of inositol hexaphosphate in transgenic adenocarcinoma of mouse prostate (TRAMP-C1) cells. Int J Oncol 23: 1413-1418, 2003.
    • (2003) Int J Oncol , vol.23 , pp. 1413-1418
    • Sharma, G.1    Singh, R.P.2    Agarwal, R.3
  • 29
    • 0029415212 scopus 로고
    • IP6-induced growth inhibition and differentiation of HT-29 human colon cancer cells: Involvement of intracellular inositol phosphates
    • Yang GY and Shamsuddin AM: IP6-induced growth inhibition and differentiation of HT-29 human colon cancer cells: Involvement of intracellular inositol phosphates. Anticancer Res 15: 2479-2487, 1995.
    • (1995) Anticancer Res , vol.15 , pp. 2479-2487
    • Yang, G.Y.1    Shamsuddin, A.M.2
  • 30
    • 0029122135 scopus 로고
    • Inositol hexaphosphate inhibits growth and induces differentiation of PC-3 human prostate cancer cells
    • Shamsuddin AM and Yang GY: Inositol hexaphosphate inhibits growth and induces differentiation of PC-3 human prostate cancer cells. Carcinogenesis 16: 1975-1979, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 1975-1979
    • Shamsuddin, A.M.1    Yang, G.Y.2
  • 32
    • 17044401289 scopus 로고    scopus 로고
    • Growth and cell viability of estradiol and IP-6 treated Hep-2 laryngeal carcinoma cells
    • Dorsey M, Benghuzzi H, Tucci M and Cason Z: Growth and cell viability of estradiol and IP-6 treated Hep-2 laryngeal carcinoma cells. Biomed Sci Instrum 41: 205-210, 2005.
    • (2005) Biomed Sci Instrum , vol.41 , pp. 205-210
    • Dorsey, M.1    Benghuzzi, H.2    Tucci, M.3    Cason, Z.4
  • 33
    • 38749090096 scopus 로고    scopus 로고
    • Corn-derived carbohydrate inositol hexaphosphate inhibits Barrett's adenocarcinoma growth by pro-apoptotic mechanisms
    • McFadden DW, Riggs DR, Jackson BJ and Cunningham C: Corn-derived carbohydrate inositol hexaphosphate inhibits Barrett's adenocarcinoma growth by pro-apoptotic mechanisms. Oncol Rep 19: 563-566, 2008.
    • (2008) Oncol Rep , vol.19 , pp. 563-566
    • McFadden, D.W.1    Riggs, D.R.2    Jackson, B.J.3    Cunningham, C.4
  • 34
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen GM: Caspases: the executioners of apoptosis. Biochem J 326 (Pt 1): 1-16, 1997.
    • (1997) Biochem J , vol.326 , Issue.PART 1 , pp. 1-16
    • Cohen, G.M.1
  • 35
    • 0344142396 scopus 로고    scopus 로고
    • Emerging roles of caspase-3 in apoptosis
    • Porter AG and Janicke RU: Emerging roles of caspase-3 in apoptosis. Cell Death Differ 6: 99-104, 1999.
    • (1999) Cell Death Differ , vol.6 , pp. 99-104
    • Porter, A.G.1    Janicke, R.U.2
  • 36
    • 0036964804 scopus 로고    scopus 로고
    • Inositol hexakisphosphate blocks tumor cell growth by activating apoptotic machinery as well as by inhibiting the Akt/NFkappaB-mediated cell survival pathway
    • Ferry S, Matsuda M, Yoshida H and Hirata M: Inositol hexakisphosphate blocks tumor cell growth by activating apoptotic machinery as well as by inhibiting the Akt/NFkappaB-mediated cell survival pathway. Carcinogenesis 23: 2031-2041, 2002.
    • (2002) Carcinogenesis , vol.23 , pp. 2031-2041
    • Ferry, S.1    Matsuda, M.2    Yoshida, H.3    Hirata, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.