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Volumn 71, Issue 6, 2009, Pages 615-621

Free radical scavenging activity of Calotropis gigantea on streptozotocin-induced diabetic rats

Author keywords

Calotropis gigantea; Diabetes; Oxidative stress; Swarnabhasma

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALKALOID; AMINO ACID; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; CALOTROPIS GIGANTEA EXTRACT; CARBOHYDRATE; CATALASE; CHLOROFORM; CHOLESTEROL; FLAVONOID; GLIBENCLAMIDE; GLYCOSIDE; LIPID; PHYTOSTEROL; PROTEIN; SAPONIN; SCAVENGER; STREPTOZOCIN; SUPEROXIDE DISMUTASE; TANNIN DERIVATIVE; TRIACYLGLYCEROL;

EID: 77249165578     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.59542     Document Type: Article
Times cited : (28)

References (49)
  • 2
    • 0025126555 scopus 로고
    • Role of free radicals and catalytic metal ions in human disease
    • Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease. Met Enzymol 1990;186:1-85.
    • (1990) Met Enzymol , vol.186 , pp. 1-85
    • Halliwell, B.1    Gutteridge, J.M.2
  • 3
    • 24344491926 scopus 로고
    • Lipid peroxidation, oxygen radicals, cell damage and antioxidant therapy
    • Halliwell B, Gutteridge JM. Lipid peroxidation, oxygen radicals, cell damage and antioxidant therapy. Lancet 1994;344:1396-1397
    • (1994) Lancet , vol.344 , pp. 1396-1397
    • Halliwell, B.1    Gutteridge, J.M.2
  • 4
    • 1642522857 scopus 로고
    • Defense against free radicals has therapeutic implications
    • Simmons KJ. Defense against free radicals has therapeutic implications. J Am Med Assn 1984;251:2187-2192
    • (1984) J Am Med Assn , vol.251 , pp. 2187-2192
    • Simmons, K.J.1
  • 5
    • 0023576328 scopus 로고
    • Alterations in free radical tissue defense mechanism in STZ-induced diabetes in rat, effects of insulin treatment
    • Wohaieb SA, Godin DV. Alterations in free radical tissue defense mechanism in STZ-induced diabetes in rat, effects of insulin treatment. Diabetes 1987;36:1014-1018
    • (1987) Diabetes , vol.36 , pp. 1014-1018
    • Wohaieb, S.A.1    Godin, D.V.2
  • 6
    • 0025978194 scopus 로고
    • Change in hepatic glutathione metabolism in diabetes
    • McLennan S, Heffermen V, Wright S. Change in hepatic glutathione metabolism in diabetes. Diabetes 1991;40:344-348
    • (1991) Diabetes , vol.40 , pp. 344-348
    • McLennan, S.1    Heffermen, V.2    Wright, S.3
  • 7
    • 33845305011 scopus 로고    scopus 로고
    • Protective effect of bezfibrate on streptozotocin-induced oxidative stress and toxicity in rats
    • Tarique A, Sharma M, Pillai KK, Haque SE, Alam MM, Zaman MS. Protective effect of bezfibrate on streptozotocin-induced oxidative stress and toxicity in rats. Toxicol 2007;229:165-172
    • (2007) Toxicol , vol.229 , pp. 165-172
    • Tarique, A.1    Sharma, M.2    Pillai, K.K.3    Haque, S.E.4    Alam, M.M.5    Zaman, M.S.6
  • 8
    • 0036237183 scopus 로고    scopus 로고
    • Evaluation of chemical constituents and free-radical scavenging activity of Swarnabhasma (gold ash) an ayurvedic drug
    • Mitra A, Chakraborty S, Auddy B, Tripathi P, Sen S, Saha AV, et al. Evaluation of chemical constituents and free-radical scavenging activity of Swarnabhasma (gold ash) an ayurvedic drug. J Ethnopharmacol 2002;80:147-153
    • (2002) J Ethnopharmacol , vol.80 , pp. 147-153
    • Mitra, A.1    Chakraborty, S.2    Auddy, B.3    Tripathi, P.4    Sen, S.5    Saha, A.V.6
  • 9
    • 0027225784 scopus 로고
    • Antidiabetic and adaptogenic properties of Momordica charantia extract: An experimental and clinical evaluation
    • Srivastava Y, Bhat HV, Verma Y, Venkaidh K. Antidiabetic and adaptogenic properties of Momordica charantia extract: An experimental and clinical evaluation. Phytother Res 1993;7:285-288
    • (1993) Phytother Res , vol.7 , pp. 285-288
    • Srivastava, Y.1    Bhat, H.V.2    Verma, Y.3    Venkaidh, K.4
  • 10
    • 0035073812 scopus 로고    scopus 로고
    • Hypoglycemic and antihyperglycemic activity of Alternifolium (Wt.) Walp. seed extracts in normal and diabetic rats
    • Rao BK Rao, Rao CH. Hypoglycemic and antihyperglycemic activity of Alternifolium (Wt.) Walp. seed extracts in normal and diabetic rats. Phytomedicine 2001;8:88-93.
    • (2001) Phytomedicine , vol.8 , pp. 88-93
    • Rao, B.K.1    Rao, C.H.2
  • 11
    • 27644534120 scopus 로고    scopus 로고
    • Antioxidant and protective effect of Calotropis procera against alloxan-induced diabetics in rats
    • Roy S, Sehgal R, Pahdy BM, Kumar VL. Antioxidant and protective effect of Calotropis procera against alloxan-induced diabetics in rats. J Ethnopharmacol 2005;102:470-473
    • (2005) J Ethnopharmacol , vol.102 , pp. 470-473
    • Roy, S.1    Sehgal, R.2    Pahdy, B.M.3    Kumar, V.L.4
  • 12
    • 74249083704 scopus 로고    scopus 로고
    • Prevention of highfructose diet induced insulin resistance by Nyctanthes arbortristis and Calotropis gigantea in rats
    • Rathod N, Raghuveer I, Chitme HR, Chandra R. Prevention of highfructose diet induced insulin resistance by Nyctanthes arbortristis and Calotropis gigantea in rats. Phcog Mag 2009;9:58-63.
    • (2009) Phcog Mag , vol.9 , pp. 58-63
    • Rathod, N.1    Raghuveer, I.2    Chitme, H.R.3    Chandra, R.4
  • 13
    • 62949168323 scopus 로고    scopus 로고
    • Hepatoprotective effect of Calotropis gigantea extract agaist carbon tetrachloride induced liver injury in rats
    • Lodhi G, Singh HK Pant K, Hussain Z. Hepatoprotective effect of Calotropis gigantea extract agaist carbon tetrachloride induced liver injury in rats. Acta Pharma 2009;59:89-96.
    • (2009) Acta Pharma , vol.59 , pp. 89-96
    • Lodhi, G.1    Singh Hk Pant, K.2    Hussain, Z.3
  • 14
    • 3042669270 scopus 로고    scopus 로고
    • Studies on anti-diarrhoeal activity of Calotropis gigantea R. Br. in experimental animals
    • Chitme HR, Chandra R, Kaushik S. Studies on anti-diarrhoeal activity of Calotropis gigantea R. Br. in experimental animals. J Pharm Pharm Sci 2004;1:70-75
    • (2004) J Pharm Pharm Sci , vol.1 , pp. 70-75
    • Chitme, H.R.1    Chandra, R.2    Kaushik, S.3
  • 15
    • 24644446899 scopus 로고    scopus 로고
    • Evaluation of antipyretic activity of Calotropis gigantea (Asclepiadaceae) in experimental animals
    • Chitme HR, Chandra R, Kaushik S. Evaluation of antipyretic activity of Calotropis gigantea (Asclepiadaceae) in experimental animals. Phytother Res 2005a;5:454-456
    • (2005) Phytother Res , vol.5 , pp. 454-456
    • Chitme, H.R.1    Chandra, R.2    Kaushik, S.3
  • 16
    • 34247197774 scopus 로고    scopus 로고
    • Evaluation of analgesic activities of Calotropis gigantea extract in vivo
    • Chitme HR, Chandra R, Kaushik S. Evaluation of analgesic activities of Calotropis gigantea extract in vivo. Asia Pac J Pharmacol 2005b;16:35-40.
    • (2005) Asia Pac J Pharmacol , vol.16 , pp. 35-40
    • Chitme, H.R.1    Chandra, R.2    Kaushik, S.3
  • 17
    • 33847715851 scopus 로고    scopus 로고
    • Evaluation of anti-inflammatory activity of Calotropis gigantea (AKANDA) in various biological systems
    • Adak M, Gupta JK. Evaluation of anti-inflammatory activity of Calotropis gigantea (AKANDA) in various biological systems. Nepal Med Coll J 2006;3:156-161
    • (2006) Nepal Med Coll J , vol.3 , pp. 156-161
    • Adak, M.1    Gupta, J.K.2
  • 18
    • 33646523581 scopus 로고    scopus 로고
    • CNS activity of Calotropis gigantea roots. Ethnopharmacogical communication
    • Argal A, Pathak AK. CNS activity of Calotropis gigantea roots. Ethnopharmacogical communication. J Ethnopharmacol 2006;106:142-145
    • (2006) J Ethnopharmacol , vol.106 , pp. 142-145
    • Argal, A.1    Pathak, A.K.2
  • 19
    • 67651095600 scopus 로고    scopus 로고
    • Wound healing activity of Calotropis gigantea root bark in rats: Ethnopharmacogical communication
    • Deshmukh PT, Fernandes J, Atul A, Toppo E. Wound healing activity of Calotropis gigantea root bark in rats: Ethnopharmacogical communication. J Ethnopharmacol 2009;125:178-181
    • (2009) J Ethnopharmacol , vol.125 , pp. 178-181
    • Deshmukh, P.T.1    Fernandes, J.2    Atul, A.3    Toppo, E.4
  • 20
    • 33847714336 scopus 로고    scopus 로고
    • Original research article: Pregnancy interceptive activity of the roots of Calotropis gigantea Linn. in rats
    • Srivastava SR, Keshri G, Bhargavana B, Singh C, Singh MM. Original research article: Pregnancy interceptive activity of the roots of Calotropis gigantea Linn. in rats. Contraception 2007;75:318-322
    • (2007) Contraception , vol.75 , pp. 318-322
    • Srivastava, S.R.1    Keshri, G.2    Bhargavana, B.3    Singh, C.4    Singh, M.M.5
  • 21
    • 33845420781 scopus 로고    scopus 로고
    • Analgesic activity of Calotropis gigantea flower
    • Pathak AK, Argal A. Analgesic activity of Calotropis gigantea flower. Fitoterapia 2007;78:40-42
    • (2007) Fitoterapia , vol.78 , pp. 40-42
    • Pathak, A.K.1    Argal, A.2
  • 22
    • 20444432804 scopus 로고    scopus 로고
    • Procoagulant activity of Calotropis gigantea latex associated with fibrin(ogen)olytic activity
    • Rajesh R, Raghavendra Gowda CD, Nataraju A, Dhananjaya BL, Kemparaju K, et al. Procoagulant activity of Calotropis gigantea latex associated with fibrin(ogen)olytic activity. Toxicon 2005;46:84-92.
    • (2005) Toxicon , vol.46 , pp. 84-92
    • Rajesh, R.1    Raghavendra Gowda, C.D.2    Nataraju, A.3    Dhananjaya, B.L.4    Kemparaju, K.5
  • 24
    • 33748789877 scopus 로고    scopus 로고
    • 19-Nor-and18,20-Epoxy-cardenolides from the leaves of Calotropis gigantea
    • Thitima L, Somyot S. 19-Nor-and18,20-Epoxy-cardenolides from the leaves of Calotropis gigantea. J Nat Prod 2006;8:1249-1251
    • (2006) J Nat Prod , vol.8 , pp. 1249-1251
    • Thitima, L.1    Somyot, S.2
  • 25
    • 36348989696 scopus 로고    scopus 로고
    • Isolation of stigmasterol and ß-sitosterol from methnolic extract of root bark of Calotropis gigantea Pak
    • Rowshanul HM, Farjana N, Matiar R, Ekramul HM, Rezaul KM. Isolation of stigmasterol and ß-sitosterol from methnolic extract of root bark of Calotropis gigantea Pak J Bio Sci 2007;22:4174-4176
    • (2007) J Bio Sci , vol.22 , pp. 4174-4176
    • Rowshanul, H.M.1    Farjana, N.2    Matiar, R.3    Ekramul, H.M.4    Rezaul, K.M.5
  • 26
    • 0026901082 scopus 로고
    • Flavonol glycosides from Calotropis gigantea
    • Sen S, Niranjan PS, Mahato SB. Flavonol glycosides from Calotropis gigantea. Phytochemistry 1992;8:2919-2921
    • (1992) Phytochemistry , vol.8 , pp. 2919-2921
    • Sen, S.1    Niranjan, P.S.2    Mahato, S.B.3
  • 27
    • 0021457126 scopus 로고
    • Comparative studies calotropin di and DII from the latex of Calotropis gigantea
    • Sengupta A, Bhattacharya D, Pal G, Sinha NK. Comparative studies calotropin DI and DII from the latex of Calotropis gigantea. Arch Biochem Biophys 1984;1:17-25.
    • (1984) Arch Biochem Biophys , vol.1 , pp. 17-25
    • Sengupta, A.1    Bhattacharya, D.2    Pal, G.3    Sinha, N.K.4
  • 28
    • 0020484334 scopus 로고
    • Crystal and molecular structure of the sulfhydryl protease calotropin di at 3.2 A° resolution
    • Heinemann U, Pal GP, Hilgenfeld R, Saenger W. Crystal and molecular structure of the sulfhydryl protease calotropin DI at 3.2 A° resolution. J Mol Biol 1982;161:591-606.
    • (1982) J Mol Biol , vol.161 , pp. 591-606
    • Heinemann, U.1    Pal, G.P.2    Hilgenfeld, R.3    Saenger, W.4
  • 29
    • 0142042928 scopus 로고    scopus 로고
    • Antidiabetic activity of ethanol extract of Cassia Klenii leaf in streptozotocin-induced diabetic rats and isolation of an active fraction and toxicity evaluation of the extract
    • Babu V, Ganadevi T, Subramoniam A. Antidiabetic activity of ethanol extract of Cassia Klenii leaf in streptozotocin-induced diabetic rats and isolation of an active fraction and toxicity evaluation of the extract. Indian J Pharmacol 2003;35:290-296
    • (2003) Indian J Pharmacol , vol.35 , pp. 290-296
    • Babu, V.1    Ganadevi, T.2    Subramoniam, A.3
  • 31
    • 69749123357 scopus 로고    scopus 로고
    • Blood glucose lowering potential of Bougainvillea spectabilis Willd. leaf extract in streptozotocin-induced type-1 diabetics albino rats
    • Purohit A, Sharma A. Blood glucose lowering potential of Bougainvillea spectabilis Willd. leaf extract in streptozotocin-induced type-1 diabetics albino rats. Indian Drugs 2006;7:538-542
    • (2006) Indian Drugs , vol.7 , pp. 538-542
    • Purohit, A.1    Sharma, A.2
  • 33
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acids reaction
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acids reaction. Anal Biochem 1979;95:351-358
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 34
    • 0015153416 scopus 로고
    • Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels
    • Beauchamp C, Fridovich I. Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels. Anal Biochem 1971;44:276-287
    • (1971) Anal Biochem , vol.44 , pp. 276-287
    • Beauchamp, C.1    Fridovich, I.2
  • 35
    • 0037077407 scopus 로고    scopus 로고
    • Studies on antioxidant activity of Pomegranate (Punica granatum) peels extract using in vivo models
    • Chidambara Murthy KN, Jayaprakasha GK, Singh RP. Studies on antioxidant activity of Pomegranate (Punica granatum) peels extract using in vivo models. J Agri Food Chem 2002;50:4791-4795
    • (2002) J Agri Food Chem , vol.50 , pp. 4791-4795
    • Chidambara Murthy, K.N.1    Jayaprakasha, G.K.2    Singh, R.P.3
  • 36
    • 0015353270 scopus 로고
    • Calorimetric assay of catalase
    • Sinha A. Calorimetric assay of catalase. Anal Biochem 1972;47:389-394
    • (1972) Anal Biochem , vol.47 , pp. 389-394
    • Sinha, A.1
  • 37
    • 20044383440 scopus 로고    scopus 로고
    • Antioxidant properties of Momordica charantia (bitter gourd) seeds on streptozotocin-induced diabetic rats
    • Sathishsekar D, Subramanian S. Antioxidant properties of Momordica charantia (bitter gourd) seeds on streptozotocin-induced diabetic rats. Asia Pac J Clin Nutri 2005;14:153-158
    • (2005) Asia Pac J Clin Nutri , vol.14 , pp. 153-158
    • Sathishsekar, D.1    Subramanian, S.2
  • 38
    • 2442649945 scopus 로고    scopus 로고
    • Effect of Helicteres isora root on glucose tolerance in glucose induced hyperglycemic rats
    • Venkatesh S, Reddy GD, Reddy YS, Satayavathy D, Reddy BM. Effect of Helicteres isora root on glucose tolerance in glucose induced hyperglycemic rats. Fitoterapia 2004;75:364-367
    • (2004) Fitoterapia , vol.75 , pp. 364-367
    • Venkatesh, S.1    Reddy, G.D.2    Reddy, Y.S.3    Satayavathy, D.4    Reddy, B.M.5
  • 39
    • 0035690454 scopus 로고    scopus 로고
    • Differential acute and long term actions of succinic acid monomethyl ester exposure on insulin secreting BRAIN-BN 11 cells
    • Picton SF, Flatt PR. Differential acute and long term actions of succinic acid monomethyl ester exposure on insulin secreting BRAIN-BN 11 cells. Int J Exp Diabetes Res 2001;2:19-27.
    • (2001) Int J Exp Diabetes Res , vol.2 , pp. 19-27
    • Picton, S.F.1    Flatt, P.R.2
  • 40
    • 39149109931 scopus 로고    scopus 로고
    • Antioxidant and pancreasprotective effect of aucubin on rats with streptozotocin-induced diabetes
    • Jin L, Xue HY, Jin LJ, Li SY, Xu YP. Antioxidant and pancreasprotective effect of aucubin on rats with streptozotocin-induced diabetes. Eur J Pharmacol 2008;582:162-167
    • (2008) Eur J Pharmacol , vol.582 , pp. 162-167
    • Jin, L.1    Xue, H.Y.2    Jin, L.J.3    Li, S.Y.4    Xu, Y.P.5
  • 41
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Met Enzymol 1984;105:121-126
    • (1984) Met Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 42
    • 17144450247 scopus 로고    scopus 로고
    • Antioxidant status in experimental type 2 diabetes mellitus: Effect of glibenclamide and glipizide on various rat tissue
    • Tuzun S, Girgin FK, Sozmen EY. Antioxidant status in experimental type 2 diabetes mellitus: Effect of glibenclamide and glipizide on various rat tissue. Exp Toxicol Pathol 1999;51:431-441
    • (1999) Exp Toxicol Pathol , vol.51 , pp. 431-441
    • Tuzun, S.1    Girgin, F.K.2    Sozmen, E.Y.3
  • 43
    • 4143063619 scopus 로고    scopus 로고
    • Effect of the sulphonylurea glibenclamide on liver and kidney antioxidant enzymes in streptozotocin-induced diabetic rats
    • Elmali E, Altan N, Bukan N. Effect of the sulphonylurea glibenclamide on liver and kidney antioxidant enzymes in streptozotocin-induced diabetic rats. Drugs RD 2004;5:203-208
    • (2004) Drugs RD , vol.5 , pp. 203-208
    • Elmali, E.1    Altan, N.2    Bukan, N.3
  • 44
    • 24044513942 scopus 로고    scopus 로고
    • A review on the role of antioxidant in the management of diabetes and its complications
    • Rahimi R, Nikfar S, Larijan B, Abdollahi M. A review on the role of antioxidant in the management of diabetes and its complications. Biomed Pharmacother 2005;59:365-373
    • (2005) Biomed Pharmacother , vol.59 , pp. 365-373
    • Rahimi, R.1    Nikfar, S.2    Larijan, B.3    Abdollahi, M.4
  • 45
  • 46
    • 0034908609 scopus 로고    scopus 로고
    • Effect of Vinca rosea extracts in treatment of alloxan diabetes in male albino rats
    • Ghosh S, Suryawansi SA. Effect of Vinca rosea extracts in treatment of alloxan diabetes in male albino rats. Indian J Exp Biol 2001;39:748-759
    • (2001) Indian J Exp Biol , vol.39 , pp. 748-759
    • Ghosh, S.1    Suryawansi, S.A.2
  • 47
    • 33745204642 scopus 로고    scopus 로고
    • Cholesterol and triglyceride lowering activity of caraway fruits in normal and streptozotocin diabetic rats
    • Lemhadri A, Hajji L, Michel JB, Eddouks M. Cholesterol and triglyceride lowering activity of caraway fruits in normal and streptozotocin diabetic rats. J Ethnopharmacol 2006;106:321-326
    • (2006) J Ethnopharmacol , vol.106 , pp. 321-326
    • Lemhadri, A.1    Hajji, L.2    Michel, J.B.3    Eddouks, M.4
  • 48
    • 11144328863 scopus 로고    scopus 로고
    • Quercetin, a flavonoid antioxidant, prevents and protects streptozotocin-induced oxidative stress and cell damage in rats pancreas
    • Omer C, Mehmet K, Ahmet K, Sukru O. Quercetin, a flavonoid antioxidant, prevents and protects streptozotocin-induced oxidative stress and cell damage in rats pancreas. Pharmacol Res 2005;51:117-123
    • (2005) Pharmacol Res , vol.51 , pp. 117-123
    • Omer, C.1    Mehmet, K.2    Ahmet, K.3    Sukru, O.4
  • 49
    • 39749098610 scopus 로고    scopus 로고
    • Antioxidant flavonoid glycosides from the leaves of Ficus pumila L
    • Abraham LCN, Masakuni T, Isao H, Hajime T. Antioxidant flavonoid glycosides from the leaves of Ficus pumila L. Food Chem 2008;109:415-420
    • (2008) Food Chem , vol.109 , pp. 415-420
    • Abraham, L.C.N.1    Masakuni, T.2    Isao, H.3    Hajime, T.4


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