CNS activity of Calotropis gigantea roots

Journal of Ethnopharmacology

Volumn 106, Issue 1, 2006, Pages 142-145

  Argal, Ameeta ^a   Pathak, Anupam Kumar ^a  

^a BARKATULLAH UNIVERSITY   (India)

Author keywords

Alcoholic extract; Analgesic; Anticonvulsant; Anxiolytic; Calotropis gigantea; Peeled roots

Indexed keywords

ACETIC ACID; ALCOHOL; CALOTROPIS GIGANTEA EXTRACT; PENTETRAZOLE; PENTOBARBITAL; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; ASCLEPIADACEAE; BODY WEIGHT; BRAIN FUNCTION; CALOTROPIS GIGANTEA; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CONVULSION; DISEASE SEVERITY; DRUG POTENTIATION; FEMALE; HOT PLATE TEST; LICKING; LOCOMOTION; MALE; MORTALITY; MOTOR COORDINATION; NONHUMAN; PLANT ROOT; RAT; SEDATION; SLEEP; TRANQUILIZING ACTIVITY; WRITHING TEST;

ANALGESICS; ANIMALS; ANTI-ANXIETY AGENTS; ANTICONVULSANTS; CALOTROPIS; CENTRAL NERVOUS SYSTEM; FEMALE; HYPNOTICS AND SEDATIVES; MALE; MOTOR ACTIVITY; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; RATS;

ANIMALIA; APOCYNACEAE; CALOTROPIS GIGANTEA;

EID: 33646523581     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2005.12.024     Document Type: Article

References (23)

1. Achliya G.S., Wadodkar S.G., and Dorle A.K. Evaluation of CNS activity of Brahmi ghrita. Indian Journal of Pharmacology 37 (2005) 33-36
2. Allen T.F. Handbook of Materia Medica and Homeopathic Therapeutics (1994), Jain Publishers (P) Ltd., New Delhi p. 251
3. Aminuddin, and Girach R.D. Observations on ethnobotany of the Bhunjia-a tribe of Sonabera plateau, Kalahandi, Orissa. Ethnobotany 5 (1993) 84
4. Boericke W. Pocket Manual of Homeopathic Materia Medica and Repertory (1999), Jain Publishers (P) Ltd., New Delhi p. 157
5. Dewan S., Sangraula H., and Kumar V.L. Preliminary studies on the analgesic activity of latex of Calotropis procera. Journal of Ethnopharmacology 73 (2000) 307-311
6. Hassenohrl R.U., Topic B., Friesch C., Hacker R., Mattern C.M., and Huston J.P. Dissociation between anxiolytic and hypomnestic effects for combined extract of Zingiber officinale and Ginkgo biloba as opposed to diazepam. Pharmacology Biochemistry and Behaviour 59 (1998) 527-535
7. Jain S.K., Sinha B.K., and Saklani A. Medicinal plants known among tribal societies of India. Ethnobotany 1 (1989) 92
8. Kahn R.S., Van Prag H.N., Wtzler S., Asnis G.M., and Barr G. Serotonin and anxiety revisited. Biological Psychiatry 23 (1988) 189-208
9. Kamath J.V., and Rana A.C. Pharmacological activities of ethanolic extract of Calotropis procera roots. Indian Drugs 40 (2003) 292-295
10. Kirtikar K.R., and Basu B.D. Indian Medicinal Plants. Sudhindhra Nath Basu, Allahabad 3 (1995) 1609
11. Kulkarni S.K. Handbook of Experimental Pharmacology. 3rd ed. (1999), Vallabh Prakashan, New Delhi pp. 133-137, 191, 199-223
12. Leewanich P., Tohda M., Matsumoto K., Subhadhirsakul S., Takayama H., and Watanbe H. Behavioural studies on alkaloids extracted from leaves of Hunteria zeylanica. Biological and Pharmaceutical Bulletin 19 (1996) 394-399
13. Manandhar M.P. Folk-lore medicine of Chitwan district, Nepal. Ethnobotany 2 (1990) 33
14. Nagarjun N.S., Soundari P.G., and Kumaresan P.T. CNS depressant activity of Dalbergia malaberica. Indian Drugs 40 (2003) 716-717
15. Pal G., and Sinha N.K. Isolation, crystallization and properties of calotropins DI and DII from Calotropis gigantea. Archives of Biochemistry and Biophysics 202 (1980) 321-329
16. Sen S., Sahu N.P., and Mahato S.B. Phytochemistry 31 (1992) 2919-2921
17. Sharma V. Dravyaguna Vigyan vol. 2 (2001), Chaukhambala Bharti Academy, Varanasi p. 435
18. Singh B., and Rastogi R.P. Structure of asclepin and some observations on the NMR spectra of Calotropis glycosides. Phytochemistry 11 (1972) 757-762
19. Sonavane G.C., Sarveiya V., Kasture V., and Kasture B.S. Behavioural actions of Myristica fragrans seed. Indian Journal of Pharmacology 33 (2001) 417-424
20. Tsuji M., Takeda H., and Matsumiya T. Multiplicity of anxiety and serotonin in nervous system. Nippon Yakurigaku Zasshi 15 (2000) 29-38
21. Turner R.A. Screening Methods in Pharmacology (1965), Academic Press, New York pp. 70, 75, 78,164
22. Upadhyaya A.S., Vartak V.D., and Kumbhojkar M.S. Ethnomedico-botanical studies in western Maharashtra, India. Ethnobotany 6 (1994) 28
23. Vogel, H.G., 2002. Drug Discovery and Evaluation, Pharmacological Assays, 2nd ed. Springer-Verlag Berlin Heidelberg, New York, p. 435.