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Volumn 6, Issue 3, 2010, Pages 273-281

Mechanisms of ketamine-involved regulation of cytochrome P450 gene expression

Author keywords

ATP; Calcium; CYPs; Cytoskeleton; Ketamine

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOCHROME P450; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; KETAMINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

EID: 77249152832     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425250903505108     Document Type: Review
Times cited : (27)

References (80)
  • 1
    • 35349027760 scopus 로고    scopus 로고
    • Ketamine
    • Craven R. Ketamine. Anaesthesia 2007;62(Suppl 1):48-53
    • (2007) Anaesthesia , vol.62 , Issue.SUPPL. 1 , pp. 48-53
    • Craven, R.1
  • 2
    • 0025895757 scopus 로고
    • Reaction and significance of cytochrome P-450 enzymes
    • Guengerich FP. Reaction and significance of cytochrome P-450 enzymes. J Biol Chem 1991;266:10019-22
    • (1991) J Biol Chem , vol.266 , pp. 10019-10022
    • Guengerich, F.P.1
  • 3
    • 33845267470 scopus 로고    scopus 로고
    • The role of cytochrome P450 enzymes in endogenous signaling pathways and environmental carcinogenesis
    • Nebert DW, Dalton TP. The role of cytochrome P450 enzymes in endogenous signaling pathways and environmental carcinogenesis. Nat Rev Cancer 2006;6:947-60
    • (2006) Nat Rev Cancer , vol.6 , pp. 947-960
    • Nebert, D.W.1    Dalton, T.P.2
  • 4
    • 0035987904 scopus 로고    scopus 로고
    • Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes
    • A good paper that describes contributions of CYP isozymes for ketamine metabolism, •
    • Hijazi Y, Boulieu R. Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes. Drug Metab Dispos 2002;30:853-8 • A good paper that describes contributions of CYP isozymes for ketamine metabolism.
    • (2002) Drug Metab Dispos , vol.30 , pp. 853-858
    • Hijazi, Y.1    Boulieu, R.2
  • 5
    • 0026047958 scopus 로고
    • Clinical study on total intravenous anaesthesia with droperidol, fentanyl and ketamine. Hepatic and renal functions following prolonged surgical operation of over 10 h
    • Kimura F, Hashimoto Y, Shimodate Y. Clinical study on total intravenous anaesthesia with droperidol, fentanyl and ketamine. Hepatic and renal functions following prolonged surgical operation of over 10 h. Masui 1991;40:1371-5
    • (1991) Masui , vol.40 , pp. 1371-1375
    • Kimura, F.1    Hashimoto, Y.2    Shimodate, Y.3
  • 6
    • 57349180886 scopus 로고    scopus 로고
    • Apoptotic insults to human HepG2 cells induced by S-(+)-ketamine occurs through activation of a Bax-mitochondria- caspase protease pathway
    • Lee ST, Wu TT, Yu PY, et al. Apoptotic insults to human HepG2 cells induced by S-(+)-ketamine occurs through activation of a Bax-mitochondria- caspase protease pathway. Br J Anaesth 2009;102:80-9
    • (2009) Br J Anaesth , vol.102 , pp. 80-89
    • Lee, S.T.1    Wu, T.T.2    Yu, P.Y.3
  • 7
    • 33846864449 scopus 로고    scopus 로고
    • Transcriptional regulation and expression of CYP3A4 in hepatocytes
    • Martínez-Jiménez CP, Jover R, Donato MT, et al. Transcriptional regulation and expression of CYP3A4 in hepatocytes. Curr Drug Metab 2007;8:185-94
    • (2007) Curr Drug Metab , vol.8 , pp. 185-194
    • Martínez-Jiménez, C.P.1    Jover, R.2    Donato, M.T.3
  • 8
    • 58149463742 scopus 로고    scopus 로고
    • Chang HC, Chen TL, Chen RM. Cytoskeleton interruption in human hepatoma HepG2 cells induced by ketamine occurs possibly through suppression of calcium mobilization and mitochondrial function. Drug Metab Dispos 2009;37:24-31 • This paper presents a link between ketamine-caused cytoskeletal remodeling and suppression of CYP3A4 expression.
    • Chang HC, Chen TL, Chen RM. Cytoskeleton interruption in human hepatoma HepG2 cells induced by ketamine occurs possibly through suppression of calcium mobilization and mitochondrial function. Drug Metab Dispos 2009;37:24-31 • This paper presents a link between ketamine-caused cytoskeletal remodeling and suppression of CYP3A4 expression.
  • 9
    • 0022998708 scopus 로고
    • Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism
    • Guengerich FP, Martin MV, Beaune PH, et al. Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism. J Biol Chem 1986;261:5051-60
    • (1986) J Biol Chem , vol.261 , pp. 5051-5060
    • Guengerich, F.P.1    Martin, M.V.2    Beaune, P.H.3
  • 10
    • 69549135927 scopus 로고    scopus 로고
    • Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: A consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2alpha (eIF2alpha)-kinase (PERK) and general control nonderepressible-2 eIF2alpha kinase (GCN2), and global translational shutoff
    • Acharya P, Engel JC, Correia MA. Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: a consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2alpha (eIF2alpha)-kinase (PERK) and general control nonderepressible-2 eIF2alpha kinase (GCN2), and global translational shutoff. Mol Pharmacol 2009;76:503-15
    • (2009) Mol Pharmacol , vol.76 , pp. 503-515
    • Acharya, P.1    Engel, J.C.2    Correia, M.A.3
  • 11
    • 0025222965 scopus 로고
    • Torsades de Pointes occurring in association with terfenadine use
    • Brian P, Monahan MD, Clifford L, et al. Torsades de Pointes occurring in association with terfenadine use. JAMA 1990;264:2788-90
    • (1990) JAMA , vol.264 , pp. 2788-2790
    • Brian, P.1    Monahan, M.D.2    Clifford, L.3
  • 12
    • 27844524011 scopus 로고    scopus 로고
    • The shape of things to come: An emerging role for protein kinase CK2 in the regulation of cell morphology and the cytoskeleton
    • Canton DA, Litchfield DW. The shape of things to come: an emerging role for protein kinase CK2 in the regulation of cell morphology and the cytoskeleton. Cell Signal 2006;18:267-75
    • (2006) Cell Signal , vol.18 , pp. 267-275
    • Canton, D.A.1    Litchfield, D.W.2
  • 13
    • 21744445111 scopus 로고    scopus 로고
    • The actin cytoskeleton: A key regulator of apoptosis and ageing?
    • Gourlay CW, Ayscough KR. The actin cytoskeleton: a key regulator of apoptosis and ageing? Nat Rev Mol Cell Biol 2005;6:583-9
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 583-589
    • Gourlay, C.W.1    Ayscough, K.R.2
  • 14
    • 33646363340 scopus 로고    scopus 로고
    • The cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics
    • Adrain C, Duriez PJ, Brumatti G, et al. The cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics. J Biol Chem 2006;281:8118-25
    • (2006) J Biol Chem , vol.281 , pp. 8118-8125
    • Adrain, C.1    Duriez, P.J.2    Brumatti, G.3
  • 15
    • 46449103334 scopus 로고    scopus 로고
    • Apoptotic insults to human chondrocytes induced by nitric oxide are involved in sequential events, including cytoskeletal remodeling, phosphorylation of mitogen-activated protein kinase kinase kinase-1, and Bax-mitochondria-mediated caspase activation
    • Cherng YG, Chang HC, Lin YL, et al. Apoptotic insults to human chondrocytes induced by nitric oxide are involved in sequential events, including cytoskeletal remodeling, phosphorylation of mitogen-activated protein kinase kinase kinase-1, and Bax-mitochondria-mediated caspase activation. J Orthop Res 2008;26:1018-26
    • (2008) J Orthop Res , vol.26 , pp. 1018-1026
    • Cherng, Y.G.1    Chang, H.C.2    Lin, Y.L.3
  • 16
    • 27944506812 scopus 로고    scopus 로고
    • Role of microtubules network in CYP genes expression
    • A good review that summarizes the current knowledge on the role of microtubules network in the regulation of drug metabolizing CYPs, •
    • Dvorak Z, Ulrichova J, Modriansky M. Role of microtubules network in CYP genes expression. Curr Drug Metab 2005;6:545-52 • A good review that summarizes the current knowledge on the role of microtubules network in the regulation of drug metabolizing CYPs.
    • (2005) Curr Drug Metab , vol.6 , pp. 545-552
    • Dvorak, Z.1    Ulrichova, J.2    Modriansky, M.3
  • 17
    • 0029859715 scopus 로고    scopus 로고
    • Cellular ATP depletion induces disruption of the spectrin cytoskeletal network
    • Molitoris BA, Dahl R, Hosford M. Cellular ATP depletion induces disruption of the spectrin cytoskeletal network. Am J Physiol 1996;271:790-8
    • (1996) Am J Physiol , vol.271 , pp. 790-798
    • Molitoris, B.A.1    Dahl, R.2    Hosford, M.3
  • 18
    • 24344449173 scopus 로고    scopus 로고
    • Calcium mobilization stimulates Dictyostelium discoideum shear-flow-induced cell motility
    • Fache S, Dalous J, Engelund M, et al. Calcium mobilization stimulates Dictyostelium discoideum shear-flow-induced cell motility. J Cell Sci 2005;118:3445-7
    • (2005) J Cell Sci , vol.118 , pp. 3445-3447
    • Fache, S.1    Dalous, J.2    Engelund, M.3
  • 19
    • 0042346294 scopus 로고    scopus 로고
    • Coenzyme q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical scavenging property
    • Papucci L, Schiavone N, Witort E, et al. Coenzyme q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical scavenging property. J Biol Chem 2003;278:28220-8
    • (2003) J Biol Chem , vol.278 , pp. 28220-28228
    • Papucci, L.1    Schiavone, N.2    Witort, E.3
  • 20
  • 21
    • 0037352539 scopus 로고    scopus 로고
    • Safety of sedation with ketamine in severe head injury patients: Comparison with sufentanil
    • Bourgoin A, Albanese J, Wereszczynski N, et al. Safety of sedation with ketamine in severe head injury patients: comparison with sufentanil. Crit Care Med 2003;31:711-17
    • (2003) Crit Care Med , vol.31 , pp. 711-717
    • Bourgoin, A.1    Albanese, J.2    Wereszczynski, N.3
  • 22
    • 0024517165 scopus 로고
    • Ketamine: An update on the first twenty-five years of clinical experience
    • Reich D, Silvay G. Ketamine: an update on the first twenty-five years of clinical experience. Can J Anaesth 1989;36:186-97
    • (1989) Can J Anaesth , vol.36 , pp. 186-197
    • Reich, D.1    Silvay, G.2
  • 23
    • 33947607998 scopus 로고    scopus 로고
    • The clinical role of NMDA receptor antagonists for the treatment of postoperative pain
    • De Kock MF, Lavand'homme PM. The clinical role of NMDA receptor antagonists for the treatment of postoperative pain. Best Prac Res Clin Anaesthesiol 2007;21:85-98
    • (2007) Best Prac Res Clin Anaesthesiol , vol.21 , pp. 85-98
    • De Kock, M.F.1    Lavand'homme, P.M.2
  • 24
    • 0020046970 scopus 로고
    • The involvement of opiate and monoaminergic neuronal systems in the analgesic effects of ketamine
    • Pekoe GM, Smith DJ. The involvement of opiate and monoaminergic neuronal systems in the analgesic effects of ketamine. Pain 1982;12:57-73
    • (1982) Pain , vol.12 , pp. 57-73
    • Pekoe, G.M.1    Smith, D.J.2
  • 25
    • 0025771275 scopus 로고
    • Mechanism of the positive inotropic effect of ketamine in isolated ferret ventricular papillary muscle
    • Cook DJ, Carton EG, Housmans PR. Mechanism of the positive inotropic effect of ketamine in isolated ferret ventricular papillary muscle. Anesthesiology 1991;74:880-8
    • (1991) Anesthesiology , vol.74 , pp. 880-888
    • Cook, D.J.1    Carton, E.G.2    Housmans, P.R.3
  • 26
    • 18344377024 scopus 로고    scopus 로고
    • Ketamine reduces nitric oxide biosynthesis in human umbilical vein endothelial cells through downregulating endothelial nitric oxide synthase expression and intracellular calcium levels
    • Chen RM, Chen TL, Lin YL, et al. Ketamine reduces nitric oxide biosynthesis in human umbilical vein endothelial cells through downregulating endothelial nitric oxide synthase expression and intracellular calcium levels. Crit Care Med 2005;33:1044-9
    • (2005) Crit Care Med , vol.33 , pp. 1044-1049
    • Chen, R.M.1    Chen, T.L.2    Lin, Y.L.3
  • 27
    • 0022634021 scopus 로고
    • Differential effects of ketamine isomers on neuronal and extraneuronal catecholamine uptake mechanisms
    • Lundy PM, Lockwood PA, Thompson G, et al. Differential effects of ketamine isomers on neuronal and extraneuronal catecholamine uptake mechanisms. Anesthesiology 1986;64:359-63
    • (1986) Anesthesiology , vol.64 , pp. 359-363
    • Lundy, P.M.1    Lockwood, P.A.2    Thompson, G.3
  • 28
    • 0034861383 scopus 로고    scopus 로고
    • Does ketamine have a role in managing severe exacerbation of asthma in adults?
    • Lau TT, Zed PJ. Does ketamine have a role in managing severe exacerbation of asthma in adults? Pharmacotherapy 2001;21:110-6
    • (2001) Pharmacotherapy , vol.21 , pp. 110-116
    • Lau, T.T.1    Zed, P.J.2
  • 29
    • 54349106888 scopus 로고    scopus 로고
    • Adverse events associated with ketamine for procedural sedation in adults
    • Strayer RJ. Nelson LS. Adverse events associated with ketamine for procedural sedation in adults. Am J Emerg Med 2008;26:985-1028
    • (2008) Am J Emerg Med , vol.26 , pp. 985-1028
    • Strayer, R.J.1    Nelson, L.S.2
  • 30
    • 0025895757 scopus 로고
    • Reaction and significance of cytochrome P-450 enzymes
    • Guengerich FP. Reaction and significance of cytochrome P-450 enzymes. J Biol Chem 1991;266:10019-22
    • (1991) J Biol Chem , vol.266 , pp. 10019-10022
    • Guengerich, F.P.1
  • 31
    • 33845267470 scopus 로고    scopus 로고
    • The role of cytochrome P450 enzymes in endogenous signaling pathways and environmental carcinogenesis
    • Nebert DW, Dalton TP. The role of cytochrome P450 enzymes in endogenous signaling pathways and environmental carcinogenesis. Nat Rev Cancer 2006;6:947-60
    • (2006) Nat Rev Cancer , vol.6 , pp. 947-960
    • Nebert, D.W.1    Dalton, T.P.2
  • 32
    • 38949094492 scopus 로고    scopus 로고
    • Cytochrome P450 and chemical toxicology
    • Guengerich FP. Cytochrome P450 and chemical toxicology. Chem Res Toxicol 2008;21:70-83
    • (2008) Chem Res Toxicol , vol.21 , pp. 70-83
    • Guengerich, F.P.1
  • 33
    • 33846455127 scopus 로고    scopus 로고
    • Functional evolution of the pregnane X receptor Export. Expert Opin Drug Metab
    • Iyer M, Reschly EJ, Krasowski MD. Functional evolution of the pregnane X receptor Export. Expert Opin Drug Metab Toxicol 2006;2:381-97
    • (2006) Toxicol , vol.2 , pp. 381-397
    • Iyer, M.1    Reschly, E.J.2    Krasowski, M.D.3
  • 34
    • 67649371482 scopus 로고    scopus 로고
    • Interactions between human cytochrome P450 enzymes and steroids: Physiological and pharmacological implications. Expert Opin Drug Metab
    • Zhang YY, Yang L. Interactions between human cytochrome P450 enzymes and steroids: physiological and pharmacological implications. Expert Opin Drug Metab Toxicol. 2009;5:621-9
    • (2009) Toxicol , vol.5 , pp. 621-629
    • Zhang, Y.Y.1    Yang, L.2
  • 35
    • 0022998708 scopus 로고
    • Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism
    • Guengerich FP, Martin MV, Beaune PH, et al. Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism. J Biol Chem 1986;261:5051-60
    • (1986) J Biol Chem , vol.261 , pp. 5051-5060
    • Guengerich, F.P.1    Martin, M.V.2    Beaune, P.H.3
  • 36
    • 0023224225 scopus 로고
    • Biotransformation of ketamine, (Z)-6-hydroxyketamine, and (E)-6-hydroxyketamine by rat, rabbit, and human liver microsomal preparations
    • Woolf TF, Adams JD. Biotransformation of ketamine, (Z)-6-hydroxyketamine, and (E)-6-hydroxyketamine by rat, rabbit, and human liver microsomal preparations. Xenobiotica 1987;17:839-47
    • (1987) Xenobiotica , vol.17 , pp. 839-847
    • Woolf, T.F.1    Adams, J.D.2
  • 37
    • 0035010954 scopus 로고    scopus 로고
    • Involvement of CYP2B6 in the N-demethylation of ketamine in human liver microsomes
    • Yanagihara Y, Kariya S, Ohtani M, et al. Involvement of CYP2B6 in the N-demethylation of ketamine in human liver microsomes. Drug Metab Dispos 2001;29:887-90
    • (2001) Drug Metab Dispos , vol.29 , pp. 887-890
    • Yanagihara, Y.1    Kariya, S.2    Ohtani, M.3
  • 38
    • 52449133102 scopus 로고    scopus 로고
    • CYP2B6: New insights into a historically overlooked cytochrome P450 isozyme
    • Wang H, Tompkins LM. CYP2B6: New insights into a historically overlooked cytochrome P450 isozyme. Curr Drug Metab 2008;9:598-610
    • (2008) Curr Drug Metab , vol.9 , pp. 598-610
    • Wang, H.1    Tompkins, L.M.2
  • 39
    • 0005527043 scopus 로고
    • Metabolic disposition of tritium-labelled ketamine
    • Chang T, Savory A, Albin M, et al. Metabolic disposition of tritium-labelled ketamine. Clin Res 1970;18:597
    • (1970) Clin Res , vol.18 , pp. 597
    • Chang, T.1    Savory, A.2    Albin, M.3
  • 40
    • 4644308675 scopus 로고    scopus 로고
    • Therapeutic drugs that behave as mechanism-based inhibitors of cytochrome P450 3A4
    • Zhou S, Chan E, Lim LY, et al. Therapeutic drugs that behave as mechanism-based inhibitors of cytochrome P450 3A4. Curr Drug Metab 2004;5:415-42
    • (2004) Curr Drug Metab , vol.5 , pp. 415-442
    • Zhou, S.1    Chan, E.2    Lim, L.Y.3
  • 41
    • 0032456884 scopus 로고    scopus 로고
    • Clinically important pharmacokinetic drug-drug interactions: Role of cytochrome P450 enzymes
    • Tanaka E. Clinically important pharmacokinetic drug-drug interactions: role of cytochrome P450 enzymes. J Clin Pharm Ther 1998;23:403-16
    • (1998) J Clin Pharm Ther , vol.23 , pp. 403-416
    • Tanaka, E.1
  • 42
    • 0037871830 scopus 로고    scopus 로고
    • Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: Comparison with grapefruit juice
    • Bailey DG, Dresser GK, Bend JR. Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice. Clin Pharmacol Ther 2003;73:529-37
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 529-537
    • Bailey, D.G.1    Dresser, G.K.2    Bend, J.R.3
  • 43
    • 33745395225 scopus 로고    scopus 로고
    • CYP induction-mediated drug interactions: In vitro assessment and clinical implications
    • Lin JH. CYP induction-mediated drug interactions: in vitro assessment and clinical implications. Pharm Res 2006;23:1089-116
    • (2006) Pharm Res , vol.23 , pp. 1089-1116
    • Lin, J.H.1
  • 44
    • 33846372558 scopus 로고    scopus 로고
    • Plant N. The human cytochrome P450 sub-family: transcriptional regulation, inter-individual variation and interaction networks. Biochim Biophys Acta 2007;1770:478-88 • A good paper that introduces the genetic regulation of CYP3A4 gene expression.
    • Plant N. The human cytochrome P450 sub-family: transcriptional regulation, inter-individual variation and interaction networks. Biochim Biophys Acta 2007;1770:478-88 • A good paper that introduces the genetic regulation of CYP3A4 gene expression.
  • 45
    • 0032169826 scopus 로고    scopus 로고
    • Li W, Harper PA, Tang BK, et al. Regulation of cytochrome P450 enzymes by aryl hydrocarbon receptor in human cells: CYP1A2 expression in the LS180 colon carcinoma cell line after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or 3-methylcholanthrene. Biochem Pharmacol 1998;56:599-612
    • Li W, Harper PA, Tang BK, et al. Regulation of cytochrome P450 enzymes by aryl hydrocarbon receptor in human cells: CYP1A2 expression in the LS180 colon carcinoma cell line after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or 3-methylcholanthrene. Biochem Pharmacol 1998;56:599-612
  • 46
    • 0036070955 scopus 로고    scopus 로고
    • Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor
    • Goodwin B, Hodgson E, D'Costa DJ, et al. Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor. Mol Pharmacol 2002;62:359-65
    • (2002) Mol Pharmacol , vol.62 , pp. 359-365
    • Goodwin, B.1    Hodgson, E.2    D'Costa, D.J.3
  • 47
    • 6944234902 scopus 로고    scopus 로고
    • Regulation of CYP3A4 by the bile acid receptor FXR: Evidence for functional binding sites in the CYP3A4 gene
    • Gnerre C, Blattler S, Kaufmann MR, et al. Regulation of CYP3A4 by the bile acid receptor FXR: evidence for functional binding sites in the CYP3A4 gene. Pharmacogenetics 2004;14:635-45
    • (2004) Pharmacogenetics , vol.14 , pp. 635-645
    • Gnerre, C.1    Blattler, S.2    Kaufmann, M.R.3
  • 48
    • 0038241793 scopus 로고    scopus 로고
    • HNF4: A central regulator of hepatocyte differentiation and function
    • Watt AJ, Garrison WD, Duncan SA. HNF4: a central regulator of hepatocyte differentiation and function. Hepatology 2003;37:1249-53
    • (2003) Hepatology , vol.37 , pp. 1249-1253
    • Watt, A.J.1    Garrison, W.D.2    Duncan, S.A.3
  • 49
    • 0017227796 scopus 로고
    • Biodisposition of ketamine in the rat: Self-induction of metabolism
    • Marietta MP, White PF, Pudwill CR, et al. Biodisposition of ketamine in the rat: self-induction of metabolism. J Pharmacol Exp Ther 1976;196:536-44
    • (1976) J Pharmacol Exp Ther , vol.196 , pp. 536-544
    • Marietta, M.P.1    White, P.F.2    Pudwill, C.R.3
  • 50
    • 0017703614 scopus 로고
    • Characterization of ketamine induction of hepatic microsomal drug metabolism
    • Marietta MP, Vore ME, Way WL, et al. Characterization of ketamine induction of hepatic microsomal drug metabolism. Biochem Pharmacol 1977;26:2451-3
    • (1977) Biochem Pharmacol , vol.26 , pp. 2451-2453
    • Marietta, M.P.1    Vore, M.E.2    Way, W.L.3
  • 51
    • 0028901416 scopus 로고
    • The influence of anesthetic agents on rat hepatic cytochromes P450 in vivo
    • Loch JM, Potter J, Bachmann KA. The influence of anesthetic agents on rat hepatic cytochromes P450 in vivo. Pharmacology 1995;50:146-53
    • (1995) Pharmacology , vol.50 , pp. 146-153
    • Loch, J.M.1    Potter, J.2    Bachmann, K.A.3
  • 52
    • 0032780945 scopus 로고    scopus 로고
    • Influence of urethane and ketamine on rat hepatic cytochrome P450 in vivo
    • Meneguz A, Fortuna S, Lorenzini P, et al. Influence of urethane and ketamine on rat hepatic cytochrome P450 in vivo. Exp Toxicol Pathol 1999;51:392-6
    • (1999) Exp Toxicol Pathol , vol.51 , pp. 392-396
    • Meneguz, A.1    Fortuna, S.2    Lorenzini, P.3
  • 53
    • 0037559371 scopus 로고    scopus 로고
    • Evaluation of possible pro- or antioxidative properties and of the interaction capacity with the microsomal cytochrome P450 system of different NMDA-receptor ligands and of taurine in vitro
    • Lupp A, Kerst S, Karge E. Evaluation of possible pro- or antioxidative properties and of the interaction capacity with the microsomal cytochrome P450 system of different NMDA-receptor ligands and of taurine in vitro. Exp Toxicol Pathol 2003;54:441-8
    • (2003) Exp Toxicol Pathol , vol.54 , pp. 441-448
    • Lupp, A.1    Kerst, S.2    Karge, E.3
  • 54
    • 26044473911 scopus 로고    scopus 로고
    • Chan WH, Sun WZ, Ueng TH. Induction of rat hepatic cytochrome P-450 by ketamine and its toxicological implications. J Toxicol Environ Health A 2005;68:1581-97 • This paper demonstrates that repetitive ketamine administration induces multiple forms of rat hepatic P-450 at the levels of catalytic activity and protein expression.
    • Chan WH, Sun WZ, Ueng TH. Induction of rat hepatic cytochrome P-450 by ketamine and its toxicological implications. J Toxicol Environ Health A 2005;68:1581-97 • This paper demonstrates that repetitive ketamine administration induces multiple forms of rat hepatic P-450 at the levels of catalytic activity and protein expression.
  • 55
    • 31144460338 scopus 로고    scopus 로고
    • Effect of propofol on ropivacaine metabolism in human liver microsomes
    • Osaka Y, Inomata S, Tanaka E, et al. Effect of propofol on ropivacaine metabolism in human liver microsomes. J Anesth 2006;20:60-3
    • (2006) J Anesth , vol.20 , pp. 60-63
    • Osaka, Y.1    Inomata, S.2    Tanaka, E.3
  • 56
    • 0141829778 scopus 로고    scopus 로고
    • Potential inhibition of cytochrome P450 3A4 by propofol in human primary hepatocytes
    • Yang LQ, Yu WF, Cao YF, et al. Potential inhibition of cytochrome P450 3A4 by propofol in human primary hepatocytes. World J Gastroenterol 2003;9:1959-62
    • (2003) World J Gastroenterol , vol.9 , pp. 1959-1962
    • Yang, L.Q.1    Yu, W.F.2    Cao, Y.F.3
  • 57
    • 0028897643 scopus 로고
    • The role of CYP enzymes in cocaine-induced liver damage
    • Pasanen M, Pellinen P, Stenback F, et al. The role of CYP enzymes in cocaine-induced liver damage. Arch Toxicol 1995;69:287-90
    • (1995) Arch Toxicol , vol.69 , pp. 287-290
    • Pasanen, M.1    Pellinen, P.2    Stenback, F.3
  • 58
    • 0033848917 scopus 로고    scopus 로고
    • Nuclear and cytoskeletal translocation and localization of heterotrimeric G-proteins
    • Willard FS, Crouch MF. Nuclear and cytoskeletal translocation and localization of heterotrimeric G-proteins. Immunol Cell Biol 2000;78:387-94
    • (2000) Immunol Cell Biol , vol.78 , pp. 387-394
    • Willard, F.S.1    Crouch, M.F.2
  • 59
    • 0031850240 scopus 로고    scopus 로고
    • The cytoskeleton and cell signaling: Component localization and mechanical coupling
    • Janmey PA. The cytoskeleton and cell signaling: component localization and mechanical coupling. Physiol Rev 1998;78:763-81
    • (1998) Physiol Rev , vol.78 , pp. 763-781
    • Janmey, P.A.1
  • 60
    • 2642515740 scopus 로고    scopus 로고
    • Disruption of the actin cytoskeleton results in nuclear factor-kappaB activation and inflammatory mediator production in cultured human intestinal epithelial cells
    • Németh ZH, Deitch EA, Davidson MT, et al. Disruption of the actin cytoskeleton results in nuclear factor-kappaB activation and inflammatory mediator production in cultured human intestinal epithelial cells. J Cell Physiol 2004;200:71-81
    • (2004) J Cell Physiol , vol.200 , pp. 71-81
    • Németh, Z.H.1    Deitch, E.A.2    Davidson, M.T.3
  • 61
    • 0028964437 scopus 로고
    • Cytoskeletal control of gene expression: Depolymerization of microtubules activates NF-kappa B
    • Rosette C, Karin M. Cytoskeletal control of gene expression: depolymerization of microtubules activates NF-kappa B. J Cell Biol 1995;128:1111-9
    • (1995) J Cell Biol , vol.128 , pp. 1111-1119
    • Rosette, C.1    Karin, M.2
  • 62
    • 33646004897 scopus 로고    scopus 로고
    • Involvement of cytoskeleton in AhR-dependent CYP1A1 expression
    • Dvorák Z, Vrzal R, Ulrichová J, et al. Involvement of cytoskeleton in AhR-dependent CYP1A1 expression. Curr Drug Metab 2006;7:301-13
    • (2006) Curr Drug Metab , vol.7 , pp. 301-313
    • Dvorák, Z.1    Vrzal, R.2    Ulrichová, J.3
  • 63
    • 0028291623 scopus 로고
    • Short and long term effects of cytoskeleton-disrupting drugs on cytochrome P450 Cyp1a-1 induction in murine hepatoma 1c1c7 cells: Suppression by the microtubule inhibitor nocodazole
    • Schöller A, Hong NJ, Bischer P, et al. Short and long term effects of cytoskeleton-disrupting drugs on cytochrome P450 Cyp1a-1 induction in murine hepatoma 1c1c7 cells: suppression by the microtubule inhibitor nocodazole. Mol Pharmacol 1994;45:944-54
    • (1994) Mol Pharmacol , vol.45 , pp. 944-954
    • Schöller, A.1    Hong, N.J.2    Bischer, P.3
  • 64
    • 0037561538 scopus 로고    scopus 로고
    • Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation
    • Dvorak Z, Modriansky M, Pichard-Garcia L, et al. Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation. Mol Pharmacol 2003;64:160-9
    • (2003) Mol Pharmacol , vol.64 , pp. 160-169
    • Dvorak, Z.1    Modriansky, M.2    Pichard-Garcia, L.3
  • 66
    • 34548226450 scopus 로고    scopus 로고
    • Nucleotide effects on the structure and dynamics of actin
    • Zheng X, Diraviyam K, Sept D. Nucleotide effects on the structure and dynamics of actin. Biophys J 2007;93:1277-83
    • (2007) Biophys J , vol.93 , pp. 1277-1283
    • Zheng, X.1    Diraviyam, K.2    Sept, D.3
  • 67
    • 0033791649 scopus 로고    scopus 로고
    • Structural insights into microtubule function
    • Nogales E. Structural insights into microtubule function. Ann Rev Biochem 2000;69:277-302
    • (2000) Ann Rev Biochem , vol.69 , pp. 277-302
    • Nogales, E.1
  • 68
    • 0034502831 scopus 로고    scopus 로고
    • How motor proteins influence microtubule polymerization dynamics
    • Andrew WH, Linda W. How motor proteins influence microtubule polymerization dynamics. J Cell Sci 2000;113:4379-89
    • (2000) J Cell Sci , vol.113 , pp. 4379-4389
    • Andrew, W.H.1    Linda, W.2
  • 69
    • 0035902995 scopus 로고    scopus 로고
    • Cell cycle regulation of myosin-V by calcium/calmodulin-dependent protein kinase II
    • Karcher RL, Roland JT, Zappacosta F, et al. Cell cycle regulation of myosin-V by calcium/calmodulin-dependent protein kinase II. Science 2001;293:1317-20
    • (2001) Science , vol.293 , pp. 1317-1320
    • Karcher, R.L.1    Roland, J.T.2    Zappacosta, F.3
  • 70
    • 1642546209 scopus 로고    scopus 로고
    • Calcium signaling is involved in dynein-dependent microtubule organization
    • Adamíková L, Straube A, Schulz I, et al. Calcium signaling is involved in dynein-dependent microtubule organization. Mol Biol Cell 2004;15:1969-80
    • (2004) Mol Biol Cell , vol.15 , pp. 1969-1980
    • Adamíková, L.1    Straube, A.2    Schulz, I.3
  • 71
    • 0031661650 scopus 로고    scopus 로고
    • Cytoskeleton and mitochondrial morphology and function
    • Rappaport L, Oliviero P, Samuel JL. Cytoskeleton and mitochondrial morphology and function. Mol Cell Biochem 1998;184:101-5
    • (1998) Mol Cell Biochem , vol.184 , pp. 101-105
    • Rappaport, L.1    Oliviero, P.2    Samuel, J.L.3
  • 72
    • 0346433989 scopus 로고    scopus 로고
    • Complex II defect via down-regulation of iron-sulfur subunit induces mitochondrial dysfunction and cell cycle delay in iron chelation-induced senescence-associated growth arrest
    • Yoon YS, Byun HO, Cho H, et al. Complex II defect via down-regulation of iron-sulfur subunit induces mitochondrial dysfunction and cell cycle delay in iron chelation-induced senescence-associated growth arrest. J Biol Chem 2003;278:51577-86
    • (2003) J Biol Chem , vol.278 , pp. 51577-51586
    • Yoon, Y.S.1    Byun, H.O.2    Cho, H.3
  • 73
    • 64049115544 scopus 로고    scopus 로고
    • Angiotensin II, mitochondria, cytoskeletal, and extracellular matrix connections: An integrating viewpoint
    • Heart Circ Physiol
    • de Cavanagh EM, Ferder M, Inserra F, et al. Angiotensin II, mitochondria, cytoskeletal, and extracellular matrix connections: an integrating viewpoint. Am J Physiol Heart Circ Physiol 2009;296:550-8
    • (2009) Am J Physiol , vol.296 , pp. 550-558
    • de Cavanagh, E.M.1    Ferder, M.2    Inserra, F.3
  • 74
    • 0019424274 scopus 로고
    • The effect of ketamine hydrochloride, a non-barbiturate parenteral anaesthetic on oxidative phosphorylation in rat liver mitochondria
    • Markham A, Cameron I, White SJ. The effect of ketamine hydrochloride, a non-barbiturate parenteral anaesthetic on oxidative phosphorylation in rat liver mitochondria. Biochem Pharmacol 1981;30:2165-8
    • (1981) Biochem Pharmacol , vol.30 , pp. 2165-2168
    • Markham, A.1    Cameron, I.2    White, S.J.3
  • 75
    • 15244354051 scopus 로고    scopus 로고
    • Suppressive effects of ketamine on macrophage functions
    • Chang Y, Chen TL, Sheu JR, et al. Suppressive effects of ketamine on macrophage functions. Toxicol Appl Pharmacol. 2005;204:27-35
    • (2005) Toxicol Appl Pharmacol , vol.204 , pp. 27-35
    • Chang, Y.1    Chen, T.L.2    Sheu, J.R.3
  • 76
    • 0035708661 scopus 로고    scopus 로고
    • Identification of respiratory complexes I and III as mitochondrial sites of damage following exposure to ionizing radiation and nitric oxide
    • Pearce LL, Epperly MW, Greenberger JS, et al. Identification of respiratory complexes I and III as mitochondrial sites of damage following exposure to ionizing radiation and nitric oxide. Nitric Oxide 2001;5:128-36
    • (2001) Nitric Oxide , vol.5 , pp. 128-136
    • Pearce, L.L.1    Epperly, M.W.2    Greenberger, J.S.3
  • 77
    • 0035092955 scopus 로고    scopus 로고
    • Inhibitory effects of etomidate and ketamine on endothelium-dependent relaxation in canine pulmonary artery
    • Ogawa K, Tanaka S, Murray PA. Inhibitory effects of etomidate and ketamine on endothelium-dependent relaxation in canine pulmonary artery. Anesthesiology 2001;94:668
    • (2001) Anesthesiology , vol.94 , pp. 668
    • Ogawa, K.1    Tanaka, S.2    Murray, P.A.3
  • 78
    • 58949098904 scopus 로고    scopus 로고
    • N-methyl-D-aspartate (NMDA) antagonists-S(+)-ketamine, dextrorphan, and dextromethorphan-act as calcium antagonists on bovine cerebral arteries
    • Kamel IR, Wendling WW, Chen D, et al. N-methyl-D-aspartate (NMDA) antagonists-S(+)-ketamine, dextrorphan, and dextromethorphan-act as calcium antagonists on bovine cerebral arteries. J Neurosurg Anesthesiol 2008;20:241-8
    • (2008) J Neurosurg Anesthesiol , vol.20 , pp. 241-248
    • Kamel, I.R.1    Wendling, W.W.2    Chen, D.3
  • 79
    • 0017057951 scopus 로고
    • Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450
    • Haugen DA, Coon MJ. Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450. J Biol Chem 1976;251:7929-39
    • (1976) J Biol Chem , vol.251 , pp. 7929-7939
    • Haugen, D.A.1    Coon, M.J.2
  • 80
    • 0027198966 scopus 로고
    • Induction and inhibition of cytochrome P-450-dependent monooxygenases in hamster tissues by ethanol
    • Ueng TH, Ueng YF, Tsai JN, et al. Induction and inhibition of cytochrome P-450-dependent monooxygenases in hamster tissues by ethanol. Toxicology 1993;81:145-54
    • (1993) Toxicology , vol.81 , pp. 145-154
    • Ueng, T.H.1    Ueng, Y.F.2    Tsai, J.N.3


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