Chronic WIN55,212-2 elicits sustained and conditioned increases in intracranial self-stimulation thresholds in the rat

Behavioural Brain Research

Volumn 209, Issue 1, 2010, Pages 114-118

  Mavrikaki, Maria ^a   Markaki, Eirini ^a   Nomikos, George G ^b   Panagis, George ^a  

^a School of Social Sciences   (Greece)

^b TAKEDA PHARMACEUTICALS   (United States)

Author keywords

Brain stimulation reward; Cannabinoid; Conditioned anhedonia; Reinforcement; Reward

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN DEPTH STIMULATION; BRAIN FUNCTION; CONDITIONING; CONTROLLED STUDY; MALE; NONHUMAN; PERCEPTIVE THRESHOLD; PRIORITY JOURNAL; RAT; SELF STIMULATION; SENSITIZATION;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BENZOXAZINES; BIOPHYSICS; CALCIUM CHANNEL BLOCKERS; CONDITIONING, OPERANT; ELECTRIC STIMULATION; MALE; MEDIAL FOREBRAIN BUNDLE; MORPHOLINES; NAPHTHALENES; RATS; RATS, SPRAGUE-DAWLEY; SELF STIMULATION; SENSORY THRESHOLDS;

EID: 77249124285     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2010.01.024     Document Type: Article

References (38)

1. Antoniou K., Galanopoulos A., Vlachou S., Kourouli T., Nahmias V., Thermos K., et al. Behavioral pharmacological properties of a novel cannabinoid 1′,1′-dithiolane delta8-THC analog, AMG-3. Behav Pharmacol 16 5-6 (2005) 499-510
2. Arnold J.C., Hunt G.E., and McGregor I.S. Effects of the cannabinoid receptor agonist CP 55,940 and the cannabinoid receptor antagonist SR 141716 on intracranial self-stimulation in Lewis rats. Life Sci 70 1 (2001) 97-108
3. Campbell K.A., Evans G., and Gallistel C.R. A microcomputer-based method for physiologically interpretable measurement of the rewarding efficacy of brain stimulation. Physiol Behav 35 3 (1985) 395-403
4. Carlezon Jr. W.A., and Chartoff E.H. Intracranial self-stimulation (ICSS) in rodents to study the neurobiology of motivation. Nat Protoc 2 11 (2007) 2987-2995
5. Cheer J.F., Kendall D.A., and Marsden C.A. Cannabinoid receptors and reward in the rat: a conditioned place preference study. Psychopharmacology 151 1 (2000) 25-30
6. Edmonds D.E., and Gallistel C.R. Parametric analysis of brain stimulation reward in the rat: III. Effect of performance variables on the reward summation function. J Comp Physiol Psychol 87 5 (1974) 876-883
7. Gardner E.L. Addictive potential of cannabinoids: the underlying neurobiology. Chem Phys Lipids 121 1-2 (2002) 267-290
8. Gardner E.L., Paredes W., Smith D., Donner A., Milling C., Cohen D., et al. Facilitation of brain stimulation reward by delta 9-tetrahydrocannabinol. Psychopharmacology 96 1 (1988) 142-144
9. Gardner E.L., and Vorel S.R. Cannabinoid transmission and reward-related events. Neurobiol Dis 5 6 Pt B (1998) 502-533
10. Justinova Z., Goldberg S.R., Heishman S.J., and Tanda G. Self-administration of cannabinoids by experimental animals and human marijuana smokers. Pharmacol Biochem Behav 81 2 (2005) 285-299
11. Kenny P.J., Koob G.F., and Markou A. Conditioned facilitation of brain reward function after repeated cocaine administration. Behav Neurosci 117 5 (2003) 1103-1107
12. Kucharski L.T., Williams J.E., and Kornetsky C. The effects of levonantradol on rewarding brain stimulation thresholds in the rat. Pharmacol Biochem Behav 19 1 (1983) 149-151
13. Lepore M., Liu X., Savage V., Matalon D., and Gardner E.L. Genetic differences in delta 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains. Life Sci 58 25 (1996) PL365-PL372
14. Maldonado R. Study of cannabinoid dependence in animals. Pharmacol Ther 95 2 (2002) 153-164
15. Maldonado R., and Rodriguez de Fonseca F. Cannabinoid addiction: behavioral models and neural correlates. J Neurosci 22 9 (2002) 3326-3331
16. Mallet P.E., and Beninger R.J. Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. Life Sci 62 26 (1998) 2431-2439
17. Markou A., and Koob G.F. Construct validity of a self-stimulation threshold paradigm: effects of reward and performance manipulations. Physiol Behav 51 1 (1992) 111-119
18. Mavrikaki M., Nomikos G.G., and Panagis G. Effects of mood stabilizers on brain reward processes in rats: studies using the intracranial self-stimulation paradigm. Eur Neuropsychopharmacol 19 3 (2009) 205-214
19. Miliaressis E., Rompre P.P., Laviolette P., Philippe L., and Coulombe D. The curve-shift paradigm in self-stimulation. Physiol Behav 37 1 (1986) 85-91
20. Oviedo A., Glowa J., and Herkenham M. Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain: a quantitative autoradiographic study. Brain Res 616 1-2 (1993) 293-302
21. Panagis G., Vlachou S., and Nomikos G.G. Behavioral pharmacology of cannabinoids with a focus on preclinical models for studying reinforcing and dependence-producing properties. Curr Drug Abuse Rev 1 3 (2008) 350-374
22. Parker L.A., and Gillies T. THC-induced place and taste aversions in Lewis and Sprague-Dawley rats. Behav Neurosci 109 1 (1995) 71-78
23. Paxinos G., and Watson C. The rat brain in stereotaxic coordinates. sixth ed. (2007), Elsevier, Amsterdam
24. Polissidis A., Chouliara O., Galanopoulos A., Rentesi G., Dosi M., Hyphantis T., et al. Individual differences in the effects of cannabinoids on motor activity, dopaminergic activity and DARPP-32 phosphorylation in distinct regions of the brain. Int J Neuropsychopharmacol 27 November (2009) 1-17
25. Quinn H.R., Matsumoto I., Callaghan P.D., Long L.E., Arnold J.C., Gunasekaran N., et al. Adolescent rats find repeated Delta(9)-THC less aversive than adult rats but display greater residual cognitive deficits and changes in hippocampal protein expression following exposure. Neuropsychopharmacology 33 5 (2008) 1113-1126
26. Rodriguez de Fonseca F., Gorriti M.A., Fernandez-Ruiz J.J., Palomo T., and Ramos J.A. Downregulation of rat brain cannabinoid binding sites after chronic delta 9-tetrahydrocannabinol treatment. Pharmacol Biochem Behav 47 1 (1994) 33-40
27. Romero J., Berrendero F., Garcia-Gil L., Ramos J.A., and Fernandez-Ruiz J.J. Cannabinoid receptor and WIN-55,212-2-stimulated [35S]GTP gamma S binding and cannabinoid receptor mRNA levels in the basal ganglia and the cerebellum of adult male rats chronically exposed to delta 9-tetrahydrocannabinol. J Mol Neurosci 11 2 (1998) 109-119
28. Romero J., Garcia-Palomero E., Castro J.G., Garcia-Gil L., Ramos J.A., and Fernandez-Ruiz J.J. Effects of chronic exposure to delta9-tetrahydrocannabinol on cannabinoid receptor binding and mRNA levels in several rat brain regions. Brain Res 46 1-2 (1997) 100-108
29. Sanchis-Segura C., and Spanagel R. Behavioural assessment of drug reinforcement and addictive features in rodents: an overview. Addict Biol 11 1 (2006) 2-38
30. Sim-Selley L.J., and Martin B.R. Effect of chronic administration of R-(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-b enzoxazinyl]-(1-naphthalenyl)methanone mesylate (WIN55,212-2) or delta(9)-tetrahydrocannabinol on cannabinoid receptor adaptation in mice. J Pharmacol Exp Ther 303 1 (2002) 36-44
31. Solinas M., Goldberg S.R., and Piomelli D. The endocannabinoid system in brain reward processes. Br J Pharmacol 154 2 (2008) 369-383
32. Stark P., Dews P.B., and Cannabinoids I. Behavioral effects. J Pharmacol Exp Ther 214 1 (1980) 124-130
33. Tanda G., and Goldberg S.R. Cannabinoids: reward, dependence, and underlying neurochemical mechanisms-a review of recent preclinical data. Psychopharmacology 169 2 (2003) 115-134
34. Vlachou S., Nomikos G.G., and Panagis G. CB1 cannabinoid receptor agonists increase intracranial self-stimulation thresholds in the rat. Psychopharmacology 179 2 (2005) 498-508
35. Vlachou S., Nomikos G.G., and Panagis G. WIN 55,212-2 decreases the reinforcing actions of cocaine through CB1 cannabinoid receptor stimulation. Behav Brain Res 141 2 (2003) 215-222
36. Vlachou S., Nomikos G.G., Stephens D.N., and Panagis G. Lack of evidence for appetitive effects of Delta 9-tetrahydrocannabinol in the intracranial self-stimulation and conditioned place preference procedures in rodents. Behav Pharmacol 18 4 (2007) 311-319
37. Whitlow C.T., Freedland C.S., and Porrino L.J. Functional consequences of the repeated administration of Delta9-tetrahydrocannabinol in the rat. Drug Alcohol Depend 71 2 (2003) 169-177
38. Wise R.A. Addictive drugs and brain stimulation reward. Annu Rev Neurosci 19 (1996) 319-340