Splicing of the mycobacteriophage bethlehem DnaB intein: Identification of a new mechanistic class of inteins that contain an obligate block f nucleophile

Journal of Biological Chemistry

Volumn 285, Issue 4, 2010, Pages 2515-2526

  Tori, Kazuo ^a,b   Dassa, Bareket ^c   Johnson, Margaret A ^d   Southworth, Maurice W ^a   Brace, Lear E ^a   Ishino, Yoshizumi ^b   Pietrokovski, Shmuel ^c   Perler, Francine B ^a  

^a NEW ENGLAND BIOLABS   (United States)

^b KYUSHU UNIVERSITY   (Japan)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL DATA; BRANCH POINTS; CONSERVED RESIDUES; ESTER BONDS; ESTER LINKAGES; HOST PROTEINS; INTEINS; MECHANISTIC DIFFERENCES; MYCOBACTERIOPHAGE; N-TERMINALS; NOVEL PROTEINS; PROTEIN PRECURSORS; PROTEIN-SPLICING; SEQUENCE COMPARISONS; SPLICE JUNCTIONS;

ESTERIFICATION; ESTERS; NUCLEOPHILES;

PROTEINS;

DNAB HELICASE; INTEIN; PROLINE; THIOL DERIVATIVE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ESCHERICHIA COLI; GENE SEQUENCE; IMMUNOREACTIVITY; MUTAGENESIS; MYCOBACTERIOPHAGE; MYCOBACTERIOPHAGE BETHLEHEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PURIFICATION; SEQUENCE ALIGNMENT; AMINO ACID SEQUENCE; BIOLOGY; CLASSIFICATION; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN PROCESSING; TEMPERATURE;

MYCOBACTERIOPHAGE BETHLEHEM;

AMINO ACID SEQUENCE; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; DNAB HELICASES; INTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MYCOBACTERIOPHAGES; PROLINE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SPLICING; SULFHYDRYL COMPOUNDS; TEMPERATURE;

EID: 77249097494     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.069567     Document Type: Article

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