Poly(lactide-co-glycolide) nanoparticle assembly for highly efficient delivery of potent therapeutic agents from medical devices

Biomaterials

Volumn 31, Issue 13, 2010, Pages 3631-3642

  Lo, Catherine T ^a   Van Tassel, Paul R ^a   Saltzman, W Mark ^a  

^a Yale University   (United States)

Author keywords

Biocompatibility; Dexamethasone; Nanoparticle; Plasmid DNA; Self assembly

Indexed keywords

BIOACTIVE AGENTS; BIOLOGICAL EFFECTS; CONTROLLED DELIVERY; DEXAMETHASONE; DEXAMETHASONES; FLUORESCENT DYES; GENE DELIVERY; IN-CELL; IN-VIVO; LUCIFERASE ACTIVITIES; LUCIFERASE GENES; MACROPHAGE CELLS; MATRIX COATING; MAXIMUM LOADING; MEDICAL DEVICES; NANOPARTICLE ASSEMBLIES; PHOSPHATE-BUFFERED SALINES; PLASMID DNA; POLY LACTIDE-CO-GLYCOLIDE; PROBE SURFACE; SURFACE ASSEMBLIES; THERAPEUTIC AGENTS; TISSUE RESPONSE; TOTAL PROTEIN;

BIOCOMPATIBILITY; BIODEGRADABLE POLYMERS; CELL CULTURE; CONTINUOUS CELL CULTURE; CONTROLLED DRUG DELIVERY; DNA; GENE TRANSFER; GENES; GROWTH KINETICS; MACROPHAGES; MICROBIOLOGY; NANOPARTICLES; PHOSPHATE COATINGS; SELF ASSEMBLY;

FUNCTIONAL POLYMERS;

DEXAMETHASONE; LUCIFERASE; NANOPARTICLE; PLASMID DNA; POLYGLACTIN;

ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENZYME ACTIVITY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSFECTION; MACROPHAGE; MEDICAL INSTRUMENTATION; NANOENCAPSULATION; NANOFABRICATION; NONHUMAN; PRIORITY JOURNAL;

DEXAMETHASONE; DNA; DRUG DELIVERY SYSTEMS; EQUIPMENT AND SUPPLIES; FLUORESCENT DYES; GENE TRANSFER TECHNIQUES; NANOPARTICLES; PARTICLE SIZE; POLYGLACTIN 910;

EID: 77249090658     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.01.048     Document Type: Article

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