Lack of pharmacokinetic interaction between amdoxovir and reduced- and standard-dose zidovudine in HIV-1-infected individuals

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 3, 2010, Pages 1248-1255

  Hurwitz, Selwyn J ^a,b   Asif, Ghazia ^a,b   Fromentin, Emilie ^a,b   Tharnish, Phillip M ^b   Schinazi, Raymond F ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ATLANTA VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMDOXOVIR; PLACEBO; ZIDOVUDINE;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL STUDY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG HALF LIFE; ENZYME KINETICS; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; MUTATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STEADY STATE; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; TREATMENT DURATION; URINALYSIS;

ADULT; ANTI-HIV AGENTS; DIOXOLANES; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; MALE; MIDDLE AGED; PURINE NUCLEOSIDES; REVERSE TRANSCRIPTASE INHIBITORS; TREATMENT OUTCOME; YOUNG ADULT; ZIDOVUDINE;

EID: 77149177021     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01209-09     Document Type: Article

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