Synthesis of α- and β-pyran naphthoquinones as a new class of antitubercular agents

Archiv der Pharmazie

Volumn 343, Issue 2, 2010, Pages 81-90

  Ferreira, Sabrina B ^a,b   Da Silva, Fernando De Carvalho ^a,b   Bezerra, Flávio A F M ^c   Lourenço, Maria C S ^c   Kaiser, Carlos R ^a   Pinto, Angelo C ^a   Ferreira, Vitor F ^b  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^c Funda??o Oswaldo Cruz   (Brazil)

Author keywords

Lapachones; Naphthoquinones; Synthesis; Tuberculostatics

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; 2 (2,4 DIMETHYLPHENYL) 3,4 DIHYDRO 2H BENZO[G]CHROMENE 5,10 DIONE; 2 (2,4 DIMETHYLPHENYL) 3,4 DIHYDRO 2H BENZO[H]CHROMENE 5,6 DIONE; 2 (4 BROMOPHENYL) 3,4 DIHYDRO 2H BENZO[G]CHROMENE 5,10 DIONE; 2 (4 BROMOPHENYL) 3,4 DIHYDRO 2H BENZO[H]CHROMENE 5,6 DIONE; 2 (4 CHLOROPHENYL) 3,4 DIHYDRO 2H BENZO[G]CHROMENE 5,10 DIONE; 2 (4 CHLOROPHENYL) 3,4 DIHYDRO 2H BENZO[H]CHROMENE 5,6 DIONE; 2 (4 FLUOROPHENYL) 3,4 DIHYDRO 2H BENZO[G]CHROMENE 5,10 DIONE; 2 (4 FLUOROPHENYL) 3,4 DIHYDRO 2H BENZO[H]CHROMENE 5,6 DIONE; 2 (4 METHOXYPHENYL) 3,4 DIHYDRO 2H BENZO[G]CHROMENE 5,10 DIONE; 2 (4 METHOXYPHENYL) 3,4 DIHYDRO 2H BENZO[H]CHROMENE 5,6 DIONE; 2 (4 NITROPHENYL) 3,4 DIHYDRO 2H BENZO[G]CHROMENE 5,10 DIONE; 2 (4 TOLYL) 3,4 DIHYDRO 2H BENZO[G]CHROMENE 5,10 DIONE; 2 (4 TOLYL) 3,4 DIHYDRO 2H BENZO[H]CHROMENE 5,6 DIONE; 2 PHENYL 3,4 DIHYDRO 2H BENZO[G]CHROMENE 5,10 DIONE; 2 PHENYL 3,4 DIHYDRO 2H BENZO[H]CHROMENE 5,6 DIONE; 4 (4 NITROPHENYL) 2 (4 TOLYL) 3,4 DIHYDRO 2H BENZO[G]CHROMENE 5,10 DIONE; 4 (4 NITROPHENYL) 2 (4 TOLYL) 3,4 DIHYDRO 2H BENZO[H]CHROMENE 5,6 DIONE; 4 (THIOPHEN 2 YL) 2 (4 TOLYL) 3,4 DIHYDRO 2H BENZO[G]CHROMENE 5,10 DIONE; 4 (THIOPHEN 2 YL) 2 (4 TOLYL) 3,4 DIHYDRO 2H BENZO[H]CHROMENE 5,6 DIONE; 4 PHENYL 2 (4 TOLYL) 3,4 DIHYDRO 2H BENZO[G]CHROMENE 5,10 DIONE; 4 PHENYL 2 (4 TOLYL) 3,4 DIHYDRO 2H BENZO[H]CHROMENE 5,6 DIONE; ALCOHOL; ALDEHYDE DERIVATIVE; CARBENE; FORMALDEHYDE; LAWSONE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; AQUEOUS SOLUTION; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DIELS ALDER REACTION; DRUG SYNTHESIS; KNOEVENAGEL CONDENSATION; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL;

ANTITUBERCULAR AGENTS; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; NAPHTHOQUINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77149148424     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200900162     Document Type: Article

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