-
1
-
-
33749563294
-
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1
-
Atkin J.D., Farg M.A., Turner B.J., Tomas D., Lysaght J.A., Nunan J., Rembach A., Nagley P., Beart P.M., Cheema S.S., Horne M.K. Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1. J. Biol. Chem. 2006, 281:30152-30165.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30152-30165
-
-
Atkin, J.D.1
Farg, M.A.2
Turner, B.J.3
Tomas, D.4
Lysaght, J.A.5
Nunan, J.6
Rembach, A.7
Nagley, P.8
Beart, P.M.9
Cheema, S.S.10
Horne, M.K.11
-
2
-
-
25444464605
-
Spinal cord trauma activates processing of xbp1 mRNA indicative of endoplasmic reticulum dysfunction
-
Aufenberg C., Wenkel S., Mautes A., Paschen W. Spinal cord trauma activates processing of xbp1 mRNA indicative of endoplasmic reticulum dysfunction. J. Neurotrauma 2005, 22:1018-1024.
-
(2005)
J. Neurotrauma
, vol.22
, pp. 1018-1024
-
-
Aufenberg, C.1
Wenkel, S.2
Mautes, A.3
Paschen, W.4
-
3
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
Calfon M., Zeng H., Urano F., Till J.H., Hubbard S.R., Harding H.P., Clark S.G., Ron D. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 2002, 415:92-96.
-
(2002)
Nature
, vol.415
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
4
-
-
1842528400
-
Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins
-
Casserly I., Topol E. Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins. Lancet 2004, 363:1139-1146.
-
(2004)
Lancet
, vol.363
, pp. 1139-1146
-
-
Casserly, I.1
Topol, E.2
-
5
-
-
0037423247
-
A war on obesity, not the obese
-
Friedman J.M. A war on obesity, not the obese. Science 2003, 299:856-858.
-
(2003)
Science
, vol.299
, pp. 856-858
-
-
Friedman, J.M.1
-
6
-
-
0035107609
-
Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model
-
Hofmann M.A., Lalla E., Lu Y., Gleason M.R., Wolf B.M., Tanji N., Ferran L.J., Kohl B., Rao V., Kisiel W., Stern D.M., Schmidt A.M. Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model. J. Clin. Invest. 2001, 107:675-683.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 675-683
-
-
Hofmann, M.A.1
Lalla, E.2
Lu, Y.3
Gleason, M.R.4
Wolf, B.M.5
Tanji, N.6
Ferran, L.J.7
Kohl, B.8
Rao, V.9
Kisiel, W.10
Stern, D.M.11
Schmidt, A.M.12
-
7
-
-
0038143287
-
Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons
-
Holtz W.A., O'Malley K.L. Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons. J. Biol. Chem. 2003, 278:19367-19377.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19367-19377
-
-
Holtz, W.A.1
O'Malley, K.L.2
-
8
-
-
59049085625
-
Effect of pranoprofen on endoplasmic reticulum stress in the primary cultured glial cells
-
Hosoi T., Sasaki M., Baba S., Ozawa K. Effect of pranoprofen on endoplasmic reticulum stress in the primary cultured glial cells. Neurochem. Int. 2009, 54:1-6.
-
(2009)
Neurochem. Int.
, vol.54
, pp. 1-6
-
-
Hosoi, T.1
Sasaki, M.2
Baba, S.3
Ozawa, K.4
-
9
-
-
56749112559
-
Endoplasmic reticulum stress induces leptin resistance
-
Hosoi T., Sasaki M., Miyahara T., Hashimoto C., Matsuo S., Yoshii M., Ozawa K. Endoplasmic reticulum stress induces leptin resistance. Mol. Pharmacol. 2008, 74:1610-1619.
-
(2008)
Mol. Pharmacol.
, vol.74
, pp. 1610-1619
-
-
Hosoi, T.1
Sasaki, M.2
Miyahara, T.3
Hashimoto, C.4
Matsuo, S.5
Yoshii, M.6
Ozawa, K.7
-
10
-
-
29244438467
-
PI3K-Akt inactivation induced CHOP expression in endoplasmic reticulum-stressed cells
-
Hyoda K., Hosoi T., Horie N., Okuma Y., Ozawa K., Nomura Y. PI3K-Akt inactivation induced CHOP expression in endoplasmic reticulum-stressed cells. Biochem. Biophys. Res. Commun. 2006, 340:286-290.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.340
, pp. 286-290
-
-
Hyoda, K.1
Hosoi, T.2
Horie, N.3
Okuma, Y.4
Ozawa, K.5
Nomura, Y.6
-
11
-
-
23044432096
-
Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease
-
Isobe C., Murata T., Sato C., Terayama Y. Increase of total homocysteine concentration in cerebrospinal fluid in patients with Alzheimer's disease and Parkinson's disease. Life Sci. 2005, 77:1836-1843.
-
(2005)
Life Sci.
, vol.77
, pp. 1836-1843
-
-
Isobe, C.1
Murata, T.2
Sato, C.3
Terayama, Y.4
-
12
-
-
0141730405
-
Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder
-
Kakiuchi C., Iwamoto K., Ishiwata M., Bundo M., Kasahara T., Kusumi I., Tsujita T., Okazaki Y., Nanko S., Kunugi H., Sasaki T., Kato T. Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder. Nat. Genet. 2003, 35:171-175.
-
(2003)
Nat. Genet.
, vol.35
, pp. 171-175
-
-
Kakiuchi, C.1
Iwamoto, K.2
Ishiwata, M.3
Bundo, M.4
Kasahara, T.5
Kusumi, I.6
Tsujita, T.7
Okazaki, Y.8
Nanko, S.9
Kunugi, H.10
Sasaki, T.11
Kato, T.12
-
13
-
-
30744450012
-
Elevated levels of homocysteine compromise blood-brain barrier integrity in mice
-
Kamath A.F., Chauhan A.K., Kisucka J., Dole V.S., Loscalzo J., Handy D.E., Wagner D.D. Elevated levels of homocysteine compromise blood-brain barrier integrity in mice. Blood 2006, 107:591-593.
-
(2006)
Blood
, vol.107
, pp. 591-593
-
-
Kamath, A.F.1
Chauhan, A.K.2
Kisucka, J.3
Dole, V.S.4
Loscalzo, J.5
Handy, D.E.6
Wagner, D.D.7
-
14
-
-
33645798615
-
Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model
-
Kikuchi H., Almer G., Yamashita S., Guégan C., Nagai M., Xu Z., Sosunov A.A., McKhann G.M., Przedborski S. Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:6025-6030.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 6025-6030
-
-
Kikuchi, H.1
Almer, G.2
Yamashita, S.3
Guégan, C.4
Nagai, M.5
Xu, Z.6
Sosunov, A.A.7
McKhann, G.M.8
Przedborski, S.9
-
15
-
-
0036523032
-
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease
-
Kruman I.I., Kumaravel T.S., Lohani A., Pedersen W.A., Cutler R.G., Kruman Y., Haughey N., Lee J., Evans M., Mattson M.P. Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease. J. Neurosci. 2002, 22:1752-1762.
-
(2002)
J. Neurosci.
, vol.22
, pp. 1752-1762
-
-
Kruman, I.I.1
Kumaravel, T.S.2
Lohani, A.3
Pedersen, W.A.4
Cutler, R.G.5
Kruman, Y.6
Haughey, N.7
Lee, J.8
Evans, M.9
Mattson, M.P.10
-
16
-
-
29244448729
-
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands
-
Lee A.H., Chu G.C., Iwakoshi N.N., Glimcher L.H. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J. 2005, 24:4368-4380.
-
(2005)
EMBO J.
, vol.24
, pp. 4368-4380
-
-
Lee, A.H.1
Chu, G.C.2
Iwakoshi, N.N.3
Glimcher, L.H.4
-
17
-
-
45849137877
-
Regulation of hepatic lipogenesis by the transcription factor XBP1
-
Lee A.H., Scapa E.F., Cohen D.E., Glimcher L.H. Regulation of hepatic lipogenesis by the transcription factor XBP1. Science 2008, 320:1492-1496.
-
(2008)
Science
, vol.320
, pp. 1492-1496
-
-
Lee, A.H.1
Scapa, E.F.2
Cohen, D.E.3
Glimcher, L.H.4
-
18
-
-
20344396838
-
Effects of homocysteine on the dopaminergic system and behavior in rodents
-
Lee E.S., Chen H., Soliman K.F., Charlton C.G. Effects of homocysteine on the dopaminergic system and behavior in rodents. Neurotoxicology 2005, 26:361-371.
-
(2005)
Neurotoxicology
, vol.26
, pp. 361-371
-
-
Lee, E.S.1
Chen, H.2
Soliman, K.F.3
Charlton, C.G.4
-
19
-
-
0034716887
-
Tripartite management of unfolded proteins in the endoplasmic reticulum
-
Mori K. Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 2000, 101:451-454.
-
(2000)
Cell
, vol.101
, pp. 451-454
-
-
Mori, K.1
-
20
-
-
34547128859
-
Involvement of endoplasmic reticulum stress after middle cerebral artery occlusion in mice
-
Morimoto N., Oida Y., Shimazawa M., Miura M., Kudo T., Imaizumi K., Hara H. Involvement of endoplasmic reticulum stress after middle cerebral artery occlusion in mice. Neuroscience 2007, 147:957-967.
-
(2007)
Neuroscience
, vol.147
, pp. 957-967
-
-
Morimoto, N.1
Oida, Y.2
Shimazawa, M.3
Miura, M.4
Kudo, T.5
Imaizumi, K.6
Hara, H.7
-
21
-
-
21844447576
-
The association of plasma homocysteine levels with serum leptin and apolipoprotein B levels in childhood obesity
-
Narin F., Atabek M.E., Karakukcu M., Narin N., Kurtoglu S., Gumus H., Coksevim B., Erez R. The association of plasma homocysteine levels with serum leptin and apolipoprotein B levels in childhood obesity. Ann. Saudi Med. 2005, 25:209-214.
-
(2005)
Ann. Saudi Med.
, vol.25
, pp. 209-214
-
-
Narin, F.1
Atabek, M.E.2
Karakukcu, M.3
Narin, N.4
Kurtoglu, S.5
Gumus, H.6
Coksevim, B.7
Erez, R.8
-
22
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh H., Matsuzawa A., Tobiume K., Saegusa K., Takeda K., Inoue K., Hori S., Kakizuka A., Ichijo H. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev. 2002, 16:1345-1355.
-
(2002)
Genes Dev.
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Inoue, K.6
Hori, S.7
Kakizuka, A.8
Ichijo, H.9
-
23
-
-
1042278009
-
Brain trauma induces X-box protein 1 processing indicative of activation of the endoplasmic reticulum unfolded protein response
-
Paschen W., Yatsiv I., Shoham S., Shohami E. Brain trauma induces X-box protein 1 processing indicative of activation of the endoplasmic reticulum unfolded protein response. J. Neurochem. 2004, 88:983-992.
-
(2004)
J. Neurochem.
, vol.88
, pp. 983-992
-
-
Paschen, W.1
Yatsiv, I.2
Shoham, S.3
Shohami, E.4
-
24
-
-
0037385160
-
Transient cerebral ischemia activates processing of xbp1 messenger RNA indicative of endoplasmic reticulum stress
-
Paschen W., Aufenberg C., Hotop S., Mengesdorf T. Transient cerebral ischemia activates processing of xbp1 messenger RNA indicative of endoplasmic reticulum stress. J. Cereb. Blood Flow Metab. 2003, 23:449-461.
-
(2003)
J. Cereb. Blood Flow Metab.
, vol.23
, pp. 449-461
-
-
Paschen, W.1
Aufenberg, C.2
Hotop, S.3
Mengesdorf, T.4
-
25
-
-
34547468248
-
Spinal cord injury induces endoplasmic reticulum stress with different cell-type dependent response
-
Penas C., Guzmán M.S., Verdú E., Forés J., Navarro X., Casas C. Spinal cord injury induces endoplasmic reticulum stress with different cell-type dependent response. J. Neurochem. 2007, 102:1242-1255.
-
(2007)
J. Neurochem.
, vol.102
, pp. 1242-1255
-
-
Penas, C.1
Guzmán, M.S.2
Verdú, E.3
Forés, J.4
Navarro, X.5
Casas, C.6
-
26
-
-
0035913294
-
Plasma cell differentiation requires the transcription factor XBP-1
-
Reimold A.M., Iwakoshi N.N., Manis J., Vallabhajosyula P., Szomolanyi-Tsuda E., Gravallese E.M., Friend D., Grusby M.J., Alt F., Glimcher L.H. Plasma cell differentiation requires the transcription factor XBP-1. Nature 2001, 412:300-307.
-
(2001)
Nature
, vol.412
, pp. 300-307
-
-
Reimold, A.M.1
Iwakoshi, N.N.2
Manis, J.3
Vallabhajosyula, P.4
Szomolanyi-Tsuda, E.5
Gravallese, E.M.6
Friend, D.7
Grusby, M.J.8
Alt, F.9
Glimcher, L.H.10
-
27
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D., Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 2007, 8:519-529.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
28
-
-
63349104307
-
Protective effect against Parkinson's disease-related insults through the activation of XBP1
-
Sado M., Yamasaki Y., Iwanaga T., Onaka Y., Ibuki T., Nishihara S., Mizuguchi H., Momota H., Kishibuchi R., Hashimoto T., Wada D., Kitagawa H., Watanabe T.K. Protective effect against Parkinson's disease-related insults through the activation of XBP1. Brain Res. 2009, 1257:16-24.
-
(2009)
Brain Res.
, vol.1257
, pp. 16-24
-
-
Sado, M.1
Yamasaki, Y.2
Iwanaga, T.3
Onaka, Y.4
Ibuki, T.5
Nishihara, S.6
Mizuguchi, H.7
Momota, H.8
Kishibuchi, R.9
Hashimoto, T.10
Wada, D.11
Kitagawa, H.12
Watanabe, T.K.13
-
29
-
-
0037075257
-
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
-
Seshadri S., Beiser A., Selhub J., Jacques P.F., Rosenberg I.H., D'Agostino R.B., Wilson P.W., Wolf P.A. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N. Engl. J. Med. 2002, 346:476-483.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 476-483
-
-
Seshadri, S.1
Beiser, A.2
Selhub, J.3
Jacques, P.F.4
Rosenberg, I.H.5
D'Agostino, R.B.6
Wilson, P.W.7
Wolf, P.A.8
-
30
-
-
34147170083
-
Involvement of ER stress in retinal cell death
-
Shimazawa M., Inokuchi Y., Ito Y., Murata H., Aihara M., Miura M., Araie M., Hara H. Involvement of ER stress in retinal cell death. Mol. Vis. 2007, 13:578-587.
-
(2007)
Mol. Vis.
, vol.13
, pp. 578-587
-
-
Shimazawa, M.1
Inokuchi, Y.2
Ito, Y.3
Murata, H.4
Aihara, M.5
Miura, M.6
Araie, M.7
Hara, H.8
-
31
-
-
5444222234
-
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum
-
Sriburi R., Jackowski S., Mori K., Brewer J.W. XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. J. Cell Biol. 2004, 167:35-41.
-
(2004)
J. Cell Biol.
, vol.167
, pp. 35-41
-
-
Sriburi, R.1
Jackowski, S.2
Mori, K.3
Brewer, J.W.4
-
32
-
-
33748430163
-
Behavioral stress and activated serotonergic neurotransmission induce XBP-1 splicing in the rat brain
-
Toda H., Suzuki G., Nibuya M., Shioda K., Nishijima K., Wakizono T., Kanda Y., Watanabe Y., Shimizu K., Nomura S. Behavioral stress and activated serotonergic neurotransmission induce XBP-1 splicing in the rat brain. Brain Res. 2006, 1112:26-32.
-
(2006)
Brain Res.
, vol.1112
, pp. 26-32
-
-
Toda, H.1
Suzuki, G.2
Nibuya, M.3
Shioda, K.4
Nishijima, K.5
Wakizono, T.6
Kanda, Y.7
Watanabe, Y.8
Shimizu, K.9
Nomura, S.10
-
33
-
-
0032190546
-
Cloning of mammalian Ire1 reveals diversity in the ER stress responses
-
Wang X.Z., Harding H.P., Zhang Y., Jolicoeur E.M., Kuroda M., Ron D. Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J. 1998, 17:5708-5717.
-
(1998)
EMBO J.
, vol.17
, pp. 5708-5717
-
-
Wang, X.Z.1
Harding, H.P.2
Zhang, Y.3
Jolicoeur, E.M.4
Kuroda, M.5
Ron, D.6
-
34
-
-
33748667752
-
Endoplasmic reticulum stress and neurodegeneration in rats neonatally infected with borna disease virus
-
Williams B.L., Lipkin W.I. Endoplasmic reticulum stress and neurodegeneration in rats neonatally infected with borna disease virus. J. Virol. 2006, 80:8613-8626.
-
(2006)
J. Virol.
, vol.80
, pp. 8613-8626
-
-
Williams, B.L.1
Lipkin, W.I.2
-
35
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida H., Matsui T., Yamamoto A., Okada T., Mori K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 2001, 107:881-891.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
36
-
-
0032054744
-
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
-
Zinszner H., Kuroda M., Wang X., Batchvarova N., Lightfoot R.T., Remotti H., Stevens J.L., Ron D. CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev. 1998, 12:982-995.
-
(1998)
Genes Dev.
, vol.12
, pp. 982-995
-
-
Zinszner, H.1
Kuroda, M.2
Wang, X.3
Batchvarova, N.4
Lightfoot, R.T.5
Remotti, H.6
Stevens, J.L.7
Ron, D.8
|