Adenoviral oncolytic suicide gene therapy for a peritoneal dissemination model of gastric cancer in mice

Annals of Surgical Oncology

Volumn 17, Issue 2, 2010, Pages 643-652

  Imamura, Yu ^a   Ishikawa, Shinji ^a   Sato, Nobutaka ^a   Karashima, Ryuichi ^a   Hirashima, Kotaro ^a   Hiyoshi, Yukiharu ^a   Nagai, Youhei ^a   Koga, Yoshikatsu ^a   Hayashi, Naoko ^a   Watanabe, Masayuki ^a   Yamada, Gen ^b   Baba, Hideo ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CRE RECOMBINASE; CYTOSINE DEAMINASE; CYTOSINE DEAMINASE URACIL PHOSPHORIBOSYLTRANSFERASE; E1A PROTEIN; E1B PROTEIN; FLUCYTOSINE; HYBRID PROTEIN; ONCOLYTIC ADENOVIRUS; UNCLASSIFIED DRUG; URACIL PHOSPHORIBOSYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER TOXICITY; LOXP SITE; MOUSE; NONHUMAN; ONCOLYTIC VIROTHERAPY; PERITONEUM METASTASIS; STOMACH CANCER; SUICIDE GENE THERAPY; VIRUS REPLICATION;

ADENOVIRIDAE; ANIMALS; CARCINOEMBRYONIC ANTIGEN; FEMALE; GENE THERAPY; GENETIC VECTORS; HUMANS; IMMUNOENZYME TECHNIQUES; INTEGRASES; MICE; MICE, INBRED BALB C; MICE, NUDE; ONCOLYTIC VIROTHERAPY; PERITONEAL NEOPLASMS; STOMACH NEOPLASMS; SURVIVAL RATE; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77149122395     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-009-0852-3     Document Type: Article

References (42)

1. DM Parkin P Pisani J Ferlay 1999 Global cancer statistics CA Cancer J Clin 49 33 64 10.3322/canjclin.49.1.33 1:STN:280:DyaK1M3hs1OrsQ%3D%3D 10200776
2. JB Dupont JR Lee GR Burton I Cohn 1978 Adenocarcinoma of the stomach: review of 1497 cases Cancer 41 941 947 10.1002/1097-0142(197803)41:3<941:: AID-CNCR2820410323>3.0.CO;2-M 638980 (Pubitemid 8313231)
3. E Yamada S Miyaishi M Yamauchi, et al. 1980 The surgical treatment of cancer of the stomach Int Surg 65 387 399 1:STN:280:DyaL3M%2FptlWkug%3D%3D 6161095
4. E Bando Y Yonemura K Miwa, et al. 1999 Intraoperative lavage for cytological examination in 1,297 patients with gastric carcinoma Am J Surg 178 256 262 10.1016/S0002-9610(99)00162-2 1:STN:280:DyaK1MvlsVGktg%3D%3D 10527450 (Pubitemid 29475109)
5. Y Yonemura E Bandou T Kawamura Y Endou T Sasaki 2006 Quantitative prognostic indicators of peritoneal dissemination of gastric cancer Eur J Surg Oncol 32 602 606 10.1016/j.ejso.2006.03.003 1:STN:280:DC%2BD28vjs12ksg%3D%3D 16617004 (Pubitemid 44063992)
6. PH Sugarbaker Y Yonemura 2000 Clinical pathway for the management of resectable gastric cancer with peritoneal seeding Oncology 58 96 107 10.1159/000012086 1:STN:280:DC%2BD3c7ntFOiuw%3D%3D 10705236
7. W Yu I Whang I Suh A Averbach D Chang PH Sugarbaker 1998 Prospective randomized trial of early postoperative intraperitoneal chemotherapy as an adjuvant to resectable gastric cancer Ann Surg 228 347 354 10.1097/00000658- 199809000-00007 1:STN:280:DyaK1cvhtlynuw%3D%3D 9742917 (Pubitemid 30191697)
8. T Nakajima M Nishi T Kajitani 1991 Improvement in treatment results of gastric cancer with surgery and chemotherapy: experience of 9,700 cases in the Cancer Institute Hospital, Tokyo Semin Surg Oncol 7 365 372 10.1002/ssu. 2980070608 1:STN:280:DyaK387gtFSjtA%3D%3D 1759085
9. K Shimada JA Ajani 1999 Adjuvant therapy for gastric carcinoma patients in the past 15 years: a review of western and oriental trials Cancer 86 1657 1668 10.1002/(SICI)1097-0142(19991101)86:9<1657::AID-CNCR6>3.0.CO;2-J 1:STN:280:DC%2BD3c%2Fhs1aqsA%3D%3D 10547537 (Pubitemid 29513033)
10. SH Noh CH Yoo HC Chung JK Roh DW Shin JS Min 2001 Early postoperative intraperitoneal chemotherapy with mitomycin C, 5-fluorouracil and cisplatin for advanced gastric cancer Oncology 60 24 30 10.1159/000055292 1:STN:280: DC%2BD3M7hvVShtw%3D%3D 11150904 (Pubitemid 32041427)
11. T Fujimura Y Yonemura K Shibata, et al. 2000 Subtotal peritonectomy with chemohyperthermic peritoneal perfusion for peritonitis carcinomatosa in gastrointestinal cancer Oncol Rep 7 809 814 1:STN:280:DC%2BD3cvhtVKktw%3D%3D 10854549
12. O Glehen F Mohamed FN Gilly 2004 Peritoneal carcinomatosis from digestive tract cancer: new management by cytoreductive surgery and intraperitoneal chemohyperthermia Lancet Oncol 5 219 228 10.1016/S1470-2045(04)01425-1 15050953 (Pubitemid 38391217)
13. HC Jeung SY Rha WI Jang SH Noh HC Chung 2002 Treatment of advanced gastric cancer by palliative gastrectomy, cytoreductive therapy and postoperative intraperitoneal chemotherapy Br J Surg 89 460 466 10.1046/j.0007-1323.2001.02048.x 1:STN:280:DC%2BD383hs1Kqtg%3D%3D 11952588 (Pubitemid 34595512)
14. Y Takei Y Saga H Mizukami T Takayama M Ohwada K Ozawa, et al. 2008 Overexpression of PTEN in ovarian cancer cells suppresses i.p. dissemination and extends survival in mice Mol Cancer Ther 7 704 711 10.1158/1535-7163.MCT-06- 0724 1:CAS:528:DC%2BD1cXjtlWgs78%3D 18347155
15. X Fu L Tao X Zhang 2007 An oncolytic virus derived from type 2 herpes simplex virus has potent therapeutic effect against metastatic ovarian cancer Cancer Gene Ther 14 480 487 10.1038/sj.cgt.7701033 1:CAS:528: DC%2BD2sXktVersLg%3D 17290283 (Pubitemid 46588192)
16. HK Yu JH Ahn HJ Lee SK Lee SW Hong Y Yoon, et al. 2005 Expression of human apolipoprotein(a) kringles in colon cancer cells suppresses angiogenesis-dependent tumor growth and peritoneal dissemination J Gene Med 7 39 49 10.1002/jgm.638 1:CAS:528:DC%2BD2MXhsFartLo%3D 15517541
17. Y Miura S Ohnami K Aoki, et al. 2005 Intraperitoneal injection of adenovirus expressing antisense K-ras RNA suppresses peritoneal dissemination of hamster syngeneic pancreatic cancer without systemic toxicity Cancer Lett 218 53 62 10.1016/j.canlet.2004.08.015 1:CAS:528:DC%2BD2MXitFeltQ%3D%3D 15639340 (Pubitemid 40082701)
18. F Tanaka K Tominaga T Arakawa, et al. 2008 Interleukin-10 gene transfer to peritoneal mesothelial cells suppresses peritoneal dissemination of gastric cancer cells due to a persistently high concentration in the peritoneal cavity Cancer Gene Ther 15 51 59 10.1038/sj.cgt.7701104 1:CAS:528:DC%2BD2sXhsVWhu7jM 17992202 (Pubitemid 350261300)
19. M Miyagi K Aoyagi S Kato K Shirouzu 2007 The TIMP-1 gene transferred through adenovirus mediation shows a suppressive effect on peritoneal metastases from gastric cancer Int J Clin Oncol 12 17 24 10.1007/s10147-006-0616-z 1:CAS:528:DC%2BD2sXjvVKlt74%3D 17380436 (Pubitemid 46472548)
20. Y Tsunemitsu S Kagawa T Fujiwara, et al. 2004 Molecular therapy for peritoneal dissemination of xenotransplanted human MKN-45 gastric cancer cells with adenovirus mediated Bax gene transfer Gut 53 554 560 10.1136/gut.2003. 021683 1:CAS:528:DC%2BD2cXjsVWgurc%3D 15016751 (Pubitemid 38372981)
21. WW Zhang 1999 Development and application of adenoviral vectors for gene therapy of cancer Cancer Gene Ther 6 113 138 10.1038/sj.cgt.7700024 1:CAS:528:DyaK1MXhvFyiurs%3D 10195879
22. KH Lan F Kanai M Omata, et al. 1997 In vivo selective gene expression and therapy mediated by adenoviral vectors for human carcinoembryonic antigen-producing gastric carcinoma Cancer Res 57 4279 4284 1:CAS:528: DyaK2sXmsFChu7s%3D 9331089
23. K Ueda M Iwahashi M Nakamori M Nakamura I Matsuura H Yamaue, et al. 2001 Carcinoembryonic antigen-specific suicide gene therapy of cytosine deaminase/5-fluorocytosine enhanced by the Cre/loxP system in the orthotopic gastric carcinoma model Cancer Res 61 6158 6162 1:CAS:528:DC%2BD3MXmt12ktb8%3D 11507067
24. T Kijima T Osaki T Kishimoto, et al. 1999 Application of the Cre recombinase/loxP system further enhances antitumor effects in cell type-specific gene therapy against carcinoembryonic antigen-producing cancer Cancer Res 59 4906 4911 1:CAS:528:DyaK1MXmslWktLk%3D 10519403
25. H Goto T Osaki S Hayashi, et al. 2001 Gene therapy utilizing the Cre/loxP system selectively suppresses tumor growth of disseminated carcinoembryonic antigen-producing cancer cells Int J Cancer 94 414 419 10.1002/ijc.1474 1:CAS:528:DC%2BD3MXnsVersLk%3D 11745423 (Pubitemid 32906074)
26. T Nishiyama Y Kawamura T Sakai, et al. 1985 Antineoplastic effects in rats of 5-fluorocytosine in combination with cytosine deaminase capsules Cancer Res 45 1753 1761 1:CAS:528:DyaL2MXhvFOltr0%3D 3978637
27. GA Chung-Faye MJ Chen DJ Kerr, et al. 2001 In vivo gene therapy for colon cancer using adenovirus-mediated, transfer of the fusion gene cytosine deaminase and uracil phosphoribosyltransferase Gene Ther 8 1547 1554 10.1038/sj.gt.3301557 1:CAS:528:DC%2BD3MXotVWisb8%3D 11704815 (Pubitemid 33061893)
28. CC Heise AM Williams S Xue M Propst DH Kirn 1999 Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy Cancer Res 59 2623 2628 1:CAS:528:DyaK1MXjs1ymsbc%3D 10363984
29. Y Sato K Tanaka I Saito, et al. 1998 Enhanced and specific gene expression via tissue-specific production of Cre recombinase using adenovirus vector Biochem Biophys Res Commun 244 455 462 10.1006/bbrc.1997.8087 1:CAS:528:DyaK1cXitVKrsL0%3D 9514856 (Pubitemid 28414104)
30. T Reid R Warren D Kirn 2002 Intravascular adenoviral agents in cancer patients: lessons from clinical trials Cancer Gene Ther 9 979 986 10.1038/sj.cgt.7700539 1:CAS:528:DC%2BD3sXhs1Oitw%3D%3D 12522437 (Pubitemid 35462561)
31. EJ Small MA Carducci G Wilding, et al. 2006 A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer Mol Ther 14 107 117 10.1016/j.ymthe.2006.02.011 1:CAS:528:DC%2BD28XmtVKqur0%3D 16690359 (Pubitemid 43899483)
32. T Tanaka J Huang H Hamada, et al. 2006 Carcinoembryonic antigen-targeted selective gene therapy for gastric cancer through FZ33 fiber-modified adenovirus vectors Clin Cancer Res 12 3803 3813 10.1158/1078-0432.CCR-06-0024 1:CAS:528:DC%2BD28XlvVSlt78%3D 16778108 (Pubitemid 44000262)
33. H Akbulut L Zhang Y Tang A Deisseroth 2003 Cytotoxic effect of replication-competent adenoviral vectors carrying L-plastin promoter regulated E1A and cytosine deaminase genes in cancers of the breast, ovary and colon Cancer Gene Ther 10 388 395 10.1038/sj.cgt.7700579 1:CAS:528: DC%2BD3sXjt1Gisr4%3D 12719708 (Pubitemid 36528782)
34. M Yamamoto J Davydova M Wang GP Siegal V Krasnykh SM Vickers, et al. 2003 Sectivity enhanced, cyclooxygenase-2 promoter-based conditionally replicative adenovirus for pancreatic cancer Gastroenterology 125 1203 1218 10.1016/S0016-5085(03)01196-X 1:CAS:528:DC%2BD3sXosFCltLk%3D 14517802 (Pubitemid 37193465)
35. M Mesnil C Piccoli G Tiraby K Willecke H Yamasaki 1996 Bystander killing effect of cancer cells by herpes simplex virus thymidine kinase gene is mediated by conneins Proc Natl Acad Sci USA 93 1831 1835 10.1073/pnas.93.5.1831 1:CAS:528:DyaK28XhsFartr4%3D 8700844 (Pubitemid 26079840)
36. S Matono T Tanaka S Sueyoshi H Yamana H Fujita K Shirouzu 2003 Bystander effect in suicide gene therapy is directly proportional to the degree of gap junctional intercellular communication in esophageal cancer Int J Oncol 23 1309 1315 1:CAS:528:DC%2BD3sXptFCkurg%3D 14532970
37. P Erbs E Regulier M Mehtali, et al. 2000 In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/uracil phosphoribosyltransferase fusion gene Cancer Res 60 3813 3822 1:CAS:528:DC%2BD3cXlt1Gkt7g%3D 10919655
38. R Tomko R Xu L Philipson 1997 HCAR and MCAR: the human and mouse cellular receptors for subgroups C adenoviruses and subgroup B coxackieviruses Proc Natl Acad Sci USA 94 3352 3356 10.1073/pnas.94.7.3352 1:CAS:528:DyaK2sXisVKnsro%3D 9096397 (Pubitemid 27157315)
39. K Miyagawa C Sakakura E Otsuji, et al. 2008 Overexpression of RegIV in peritoneal dissemination of gastric cancer and its potential as A novel marker for the detection of peritoneal micrometastasis Anticancer Res 28 1169 1179 1:CAS:528:DC%2BD1cXmt1ehtLg%3D 18505053
40. DM Goldenberg RM Sharkey FJ Primus 1976 Carcinoembryonic antigen in histopathology: immunoperoxidase staining of conventional tissue sections J Natl Cancer Inst 57 11 22 1:STN:280:DyaE2s%2FnsVajtA%3D%3D 794493
41. H Dvory-Sobol E Sagiv E Liberman D Kazanov N Arber 2007 Suppression of gastric cancer cell growth by targeting the beta-catenin/T-cell factor pathway Cancer 109 188 197 10.1002/cncr.22416 1:CAS:528:DC%2BD2sXhs1yrs7w%3D 17149756 (Pubitemid 46106233)
42. DA Heideman PJ Snijders WR Gerritsen, et al. 2001 Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAMtargeted adenoviral vectors Cancer Gene Ther 8 342 351 10.1038/sj.cgt.7700313 1:CAS:528: DC%2BD3MXlsVOju7w%3D 11477454 (Pubitemid 32691124)