Molecular therapy for peritoneal dissemination of xenotransplanted human MKN-45 gastric cancer cells with adenovirus mediated Bax gene transfer

Gut

Volumn 53, Issue 4, 2004, Pages 554-560

  Tsunemitsu, Y ^a   Kagawa, S ^a,b   Tokunaga, N ^a   Otani, S ^a   Umeoka, T ^a   Roth, J A ^c   Fang, B ^c   Tanaka, N ^a   Fujiwara, T ^a,b  

^a OKAYAMA UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY HOSPITAL   (Japan)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; PROTEIN BAX; PROTEIN P53;

ANIMAL TISSUE; ARTICLE; CANCER TRANSPLANTATION; CONTROLLED STUDY; FEMALE; GENE TRANSFER; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUDE MOUSE; PERITONEUM METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH CANCER; TUMOR XENOGRAFT;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL DIVISION; FEMALE; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; PERITONEAL NEOPLASMS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; STOMACH NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 1642355989     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2003.021683     Document Type: Article

References (29)

1. Wanebo HJ, Kennedy BJ, Chmie J, et al. Cancer of the stomach. A patient care study by the American Collage of Surgeons. Ann Surg 1993;218:583-92.
2. Roth JA, Nguyen D, Lawrence DD, et al. Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nat Med 1996;2:985-91.
3. Swisher SG, Roth JA, Nemunaitis J, et al. Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer. J Natl Cancer Inst 1999;91:763-71.
4. Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-31.
5. Fujiworo T, Grimm EA, Mukhopadhyay T, et al. Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene. Cancer Res 1994;54:2287-91.
6. Spitz FR, Nguyen D, Skibber JM, et al. In vivo adenovirus-mediated p53 tumor suppressor gene therapy for colorectal cancer. Anticancer Res 1996;16:3415-22.
7. Bouvet M, Bold RJ, Lee J, et al. Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer. Ann Surg Oncol 1998;5:681-8.
8. Nielsen LL, Lipari P, Dell J, et al. Adenovirus-mediated p53 gene therapy and paclitaxel have synergistic efficacy in models of human head and neck, ovarian, prostate, and breast cancer. Clin Cancer Res 1998;4:835-46.
9. Tatebe S, Matsuura T, Endo K, et al. Adenovirus-mediated transfer of wild-type p53 gene results in apoptosis or growth arrest in human cultured gastric cancer cells. Int J Oncol 1999;15:229-35.
10. Ohashi M, Kanai F, Ueno H, et al. Adenovirus mediated p53 tumor suppressor gene therapy for human gastric cancer cells in vitro and in vivo. Gut 1999;44:366-71.
11. Shimada H, Shimizu T, Ochiai T, et al. Preclinical study of adenoviral p53 gene therapy for esophageal cancer. Surg Today 2001;31:597-604.
12. Harris MP, Sutjipto S, Wills KN, et al. Adenovirus-mediated p53 gene transfer inhibits growth of human tumor cells expressing mutant p53 protein. Cancer Gene Ther 1996;3:121-30.
13. Kagawa S, Gu J, Swisher SG, et al. Antitumor effect of adenovirus-mediated Bax gene transfer on p53-sensitive and p53-resistant cancer lines. Cancer Res 2000;60:1157-61.
14. Jurgensmeier JM, Xie Z, Deveraux Q, et al. Bax directly induces release of cytochrome c from isolated mitochondria. Proc Natl Acad Sci U S A 1998;95:4997-5002.
15. Pastorino JG, Chen ST, Tafani M, et al. The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition. J Biol Chem 1998;273:7770-5.
16. Kagawa S, Pearson SA, Ji L, et al. A binary adenoviral vector for expressing high levels of the proapoptotic gene bax. Gene Ther 2000;7:75-9.
17. Ji L, Bouvet M, Price RE, et al. Reduced toxicity, attenuated immunogenicity and efficient mediation of human p53 gene expression in vivo by an adenovirus vector with deleted E1, E3 and inactivated E4 by GAL4-TATA promoter replacement. Gene Ther 1999;6:393-402.
18. Fang B, Ji L, Bouvet M, et al. Evaluation of GAL4/TATA in vivo. Induction of transgene expression by adenovirally mediated gene codelivery. J Biol Chem 1998;273:4972-5.
19. Roehm NW, Rodgers GH, Hatfield SM, et al. An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT. J Immunol Methods 1991;142:257-65.
20. Mrozek A, Petrowsky H, Sturm I, et al. Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability. Cell Death Differ 2003;10:461-7.
21. Wagener C, Bargou RC, Daniel PT, et al. Antitumor activity of bax and p53 naked gene bax-α sensitizes cultured breast cancer cells to drug-induced apoptosis. Int J Cancer 1996;67:138-41.
22. Strobel T, Swanson L, Korsmeyer T, et al. BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway. Proc Natl Acad Sci U S A 1996;93:14094-9.
23. Sakakura C, Sweeney EA, Shirahama T, et al. Overexpression of bax sensitizes human breast cancer MCF-7 cells to radiation-induced apoptosis. Int J Cancer 1996;67:101-5.
24. Li X, Marani M, Yu J, et al. Adenovirus-mediated Bax overexpression for the induction of therapeutic apoptosis in prostate cancer. Cancer Res 2001;61:186-91.
25. Honda T, Kagawa S, Spurgers KB, et al. A recombinant adenovirus expressing wild-type Bax induces apoptosis in prostate cancer cells independently of their Bcl-2 status and androgen sensitivity. Cancer Biol Ther 2002;1:163-7.
26. Horimoto M, Sasaki Y, Ugawa S, et al. A novel strategy for cancer therapy by mutated mammalian degenerin gene transfer. Cancer Gene Ther 2000;7:1341-7.
27. Iinumo H, Maruyama K, Okinaga K, et al. Intracellular targeting therapy of cisplatin-encapsulated transferrin-polyethylene glycol liposome on peritoneal dissemination of gastric cancer. Int J Cancer 2002;99:130-7.
28. Grace MJ, Xie L, Musco ML, et al. The use of laser scanning cytometry to assess depth of penetration of adenovirus p53 gene therapy in human xenograft biopsies. Am J Pathol 1999;155:1869-78.
29. Saimura M, Nagai E, Mizumoto K, et al. Intraperitoneal injection of adenovirus-mediated NK4 gene suppresses peritoneal dissemination of pancreatic cancer cell line AsPC-1 in nude mice. Cancer Gene Ther 2002;9:799-806.